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AFM image of nanofibrous gel SEM image of cell on glass Fluorescence image of fibroblasts in nanofibrous gel Fluorescence image of cell on fibre Fluorescence image of cell on glass Group photo 2014

Publications

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2019

Zarate-Trivino DG, Pool H, Vergara-Castaneda H, Elizalde-Pena EA, Vallejo-Becerra V, Villasenor F, Prokhorov E, Julie Gough, Garcia-Gaitan B, Luna-Barcenas G. Chitosan-g-glycidyl methacrylate-collagen II scaffold for cartilage regeneration. International Journal of Polymeric Materials and Polymeric Biomaterials 2019.

Zhou F-L, Wu H, McHugh DJ, Wimpenny I, Zhang X, Gough JE, Hubbard Cristinacce PL, Parker GJM. Co-electrospraying of tumour cell mimicking hollow polymeric microspheres for diffusion magnetic resonance imaging. Materials Science and Engineering:C 2019:101;217-227.

2018

Magaz A, Faroni A, Gough JE, Reid AJ, Li X, Blaker J. Bioactive silk-based nerve guidance conduits for augmenting peripheral nerve repair. Advanced Healthcare Materials 2018;7(23).

Craven FL, Silva J, Segarra-Maset MD, Huang K, Both P, Gough JE, Flitsch SL, Webb SJ. "One-pot" sequential enzymatic modification of synthetic glycolipids in vesicle membranes. Chemical Communications 2018;54:1347-1350.

Wang QG, Wimpenny I, Dey RE, Zhong X, Youle PJ, Downes S, Watts DC, Budd PM, Hoyland JA, Gough JE. The unique calcium chelation property of poly(vinyl phosphonic acid-co-acrylic acid) and effects on osteogenesis in vitro. Journal of Biomedical Materials Research Part A 2018;106(1).

Zhou F, Li Z, Gough JE, Hubbard Cristinacce PL, Parker GJM. Axon mimicking hydrophillic hollow polycaprolactone microfibres for diffusion magnetic resonance imaging. Materials & Design 2018;137:394-403.

2017

Kumar D, Workman VL, O'Brien M, McLaren J, White L, Ragunath K, Rose F, Saiani A, Gough JE. Peptide hydrogels: A tissue engineering strategy for the prevention of oesophageal strictures 2017. In Press: Advanced Functional Materials

Coverdale BDM, Gough JE, Sampson WW, Hoyland JA. Use of lecithin to control fibre morphology in electrospun poly (ε-caprolactone) scaffolds for improved tissue engineering applications. In press: Journal of Biomedical Materials Research Part A.

Townsend L, Williams RL, Anuforom O, Berwick MR, Halstead F, Hughes E, Stamboulis A, Oppenheim B, Gough J, Grover L, Schott RAH, Webber M, Peacock AFA, Belli A, Logan A, de Cogan F. Antimicrobial peptide coatings for hydroxyapatite: electrostatic and covalent attachment of antimicrobial peptides to surfaces. Joural of the Royal Society Interface 2017;14(126):20160657. http://dx.doi.org/10.1098/rsif.2016.0657

2016

Wan S, Borland S, Richardson SM, Merry CLR, Saiani A, Gough JE. Self-assembling peptide hydrogel for intervertebral disc tissue engineering. Acta Biomaterialia 2016;46:29-40.

Marques DR, dos Santos LAL, O'Brien MA, Cartmell SH, Gough JE. In vitro evaluation of poly(lactic-co-glycolic acid)/polyisoprene fibres for soft tissue engineering. In Press: Journal of Biomedical Materials Research Part B 2016; DOI: 10.1002/jbm.b.33796

Castillo Diaz L, Elsawy M, Saiani A, Gough JE, Miler AF. Osteogenic differentiation of human mesenchymal stem cells promotes mineralization within a biodegradable peptide hydrogel. Journal of Tissue Engineering 2016;7:1-15. DOI: 10.1177/2041731416649789

Dey R, Zhong X, Youle P, Wang QG, Wimpenny I, Downes S, Hoyland J, Watts D, Gough J, Budd P. Synthesis and characterization of poly(vinylphosphonic acid-co-acrylic acid) copolymers for application in bone tissue scaffolds. Macromolecules 2016;49(7):2656-2662.

King PJS, Lizio MG, Booth A, Collins RF, Gough J, Miller A, Webb S. A modular self-assembly approach to functionalised beta-sheet peptide hydrogel biomaterials. Soft Matter 2016;12:1915-1923. DOI: 10.1039/C5SM02039E

2015

Coxon TP, Fallows TW, Gough JE, Webb S. A versatile approach towards multivalent saccharide displays on magnetic nanoparticles and phospholipid vesicles. Organic and Biomolecular Chemistry 2015;13:10751-10761. DOI: 10.1039/C5OB01591J

Yuan X, Zhou M, Glidle A, Gough JE, Yin H. A novel culture system for modulating single cell geometry in 3D. Acta Biomaterialia 2015;24:228-240.

Zhou M, Yuan X, Yin H, Gough JE. Restoration of chondrocytic phenotype on a 2-dimensional micropatterned surface. Biointerphases 2015; volume 10.

Booth A, Pintre IC, Lin Y, Gough JE, Webb SJ. Release of proteins and enzymes from vesicular compartments by alternating magnetic fields. Physical Chemistry Chemical Physics 2015;17:15579-15588.

Sabree I, Gough JE, Derby B. Mechanical properties of porous ceramic scaffolds: Influence of internal dimensions. Ceramics International 2015;41:8425-8432.

2014

Coxon TP, Almond A, Gough JE, Webb SJ. Catechol-hydrazone conjugates for the rapid functionalization of magnetite nanoparticles with cell targeting groups. MRS Proceedings 2014; 1688.

Booth A, Coxon TP, Gough JE, Webb SJ. Targeting of a magnetic bionanomaterial to HepG2 human hepatocellular carcinoma cells using a galactose terminated lipid. MRS Proceedings 2014; 1688.

Szkolar L, Guilbaud JB, Miller A, Gough JE, Saiani A. Enzymatically triggered peptide hydrogels for 3D cell encapsulation and culture. In Press: Journal of Peptide Science.

Castillo-Diaz L, Saiani A, Gough JE, Miller A. Human osteoblasts within soft peptide hydrogels promote mineralisation in vitro. Journal of Tissue Engineering 2014;5.

Zhou M, Ulijn RV, Gough JE. Extracellular matrix formation in self-assembled minimalistic bioactive hydrogels based on aromatic peptide amphiphiles. Journal of Tissue Engineering 2014 volume 5. DOI: 10.1177/2041731414531593

Dugan J, Cartmell SH, Gough JE. Uniaxial cyclic strain of human adipose derived mesenchymal stem cells and C2C12 myoblasts in coculture. Journal of Tissue Engineering 2014 volume 5. DOI: 10.1177/2041731414530138

Ghag AK, Gough JE, Downes S. Osteoblast and osteoclast responses to phosphonic acid containing poly(caprolactone) electrospun scaffolds. Biomaterials Science 2014;2:233-241.

2013

De Cogan F, Booth A, Gough JE, Webb SJ. Spatially-controlled apoptosis induced by released nickel(II) within a magnetically responsive nanostructured biomaterial. Soft Matter 2013;9(7):2245-2253.

Dugan J, Gough JE, Eichhorn SJ. Bacterial Cellulose Scaffolds and Cellulose Nanowhiskers for Tissue Engineering. Nanomedicine 2013;8(2):287-298.

Elizalde L, Sanchez, Medina-Torres L, Zarate D, Villasenor F, Gough JE, Luna G. Synthesis and characterization of a hybrid (chitosan-g-glycidyl methacrylate)-xanthan hydrogel. Journal of Biomaterials Science: Polymer Edition 2013;24(12):1426-1442.

Tripathi G, Gough JE, Dinda A, Basu B. In vitro cytotoxicity and in vivo osseointergration properties of compression molded HDPE-HA-Al2O3 hybrid biocomposites. Journal of Biomedical Materials Research Part A 2013;101A(6):1539-1549.

Dugan J, Gough JE, Eichhorn SJ. Oriented Surfaces of Adsorbed Cellulose Nanowhiskers Promote Skeletal Muscle Myogenesis. Acta Biomaterialia 2013;9:4707-4715.

Mujeeb A, Miller AF, Saiani A, Gough JE. Self-assembled octapeptide scaffolds for in vitro chondrocyte culture. Acta Biomaterialia 2013;9:4609-4617.

2012

Chopra K, Mummery PM, Derby B, Gough JE. Gel-cast glass-ceramic tissue scaffolds of controlled architecture produced via stereolithography of moulds. Biofabrication 2012;4.

Rathbone SR, Glossop JR, Gough JE, Cartmell S. Cyclic tensile strain upon human mesenchymal stem cells in 2D and 3D culture differentially influences CCNL2, WDR61 and BAHCC1 gene expression levels. Journal of the Mechanical Behaviour of Biomedical Materials 2012;11:82-91.

Gough JE, Saiani A, Miller AF. Peptide hydrogels: mimicking the extracellular matrix. Bioinspired, Biomimetic and Nanobiomaterials 2012;1(1):4-12.

Bassi AK, Gough JE, Zakikhani M, Downes S. The use of a novel phosphonate for the repair of critical size bone defects. In Press: Journal of Tissue Engineering and Regenerative Medicine.

2011

De Cogan F, Booth A, Gough JE, Webb SJ. Conversion of Magnetic Impulses into Cellular Responses by Self-Assembled Nanoparticle-Vesicle Hydrogels. Angewandte Chemie International Edition 2011;50(51):12290-12293.

Bassi AK, Gough JE, Zakikhani M, Downes S. The Chemical and Physical Properties of PCL Scaffolds functionalised with Poly(vinyl phosphonic acid-co-acrylic acid). Journal of Tissue Engineering. Volume 2011 (2011), Article ID 615328, 9 pages.

De Cogan F, Gough JE, Webb SJ. Adhesive Interactions Between Cells and Biotinylated Phospholipid Vesicles in Alginate: Towards New Responsive Biomaterials. Journal of Materials Science Materials in Medicine 2011;22(4):1045-1051.

Helen W, de Leonardis P, Ulijn RV, Gough J, Tirelli N. Mechanosensitive peptide gelation: mode of agitation controls mechanical properties and nano-scale morphology. Soft Matter 2011;7:1732-1740.

2010

Dugan J, Gough JE, Eichhorn SJ. Directing the morphology and differentiation of skeletal muscle cells using oriented cellulose nanowhiskers. Biomacromolecules 2010;11(9):2498-2504.

Kalaskar DM, Ulijn RV, Gough JE, Alexander MR, Scurr DJ, Sampson WW, Eichhorn SJ. Characterisation of Amino Acid Modified Cellulose Surfaces using ToF-SIMS and XPS. Cellulose 2010, 17:747-756.

Aviss KJ, Gough JE, Downes S. Aligned electrospun polymer fibres for skeletal muscle regeneration. European Cells and Materials 2010;19:193-204.

Leng F, Gough JE, Webb SJ. Enhancing cell culture in magnetic vesicle gels. Materials Research Society Symposia Proceedings 2010, 1272, 1272-PP07-02.

Whiteside P, Matykina E, Gough JE, Skeldon P, Thompson GE. In vitro evaluation of cell proliferation and collagen synthesis on titanium following plasma electrolytic oxidation. Journal of Biomedical Materials Research Part A 2010;94A(1):38-46.

2009

Todd SJ, Scurr DJ, Gough JE, Alexander MR, Ulijn RV. Enzyme-activated RGD ligands on functionalised PEG monolayers: surface analysis and cellular response. Langmuir 2009;25:7533-7539.

Jayawarna V, Richardson SM, Hirst A, Hodson NW, Saiani A, Gough JE, Ulijn RV. Introducing chemical functionality in Fmoc-peptide gels for cell culture. Acta Biomaterialia, 2009;5(3):934-943.

Zhou M, Smith AM, Das AK, Hodson NW, Collins RF, Ulijn RV, Gough JE. Self-assembled peptide-based hydrogels as scaffolds for anchorage dependent cells. Biomaterials 2009;30:2523-2530.

2008

Kalaskar DM, Gough JE, Ulijn RV, Sampson WW, Scurr DJ, Rutten FJ, Alexander MR, Merry CLR, EichhornSJ. Controlling cell morphology on amino acid modified cellulose. Soft Matter 2008;4:1059-1065.

Yan H, Nykanen A, Ruokolainen J, Farrar D, Gough JE, Saiani A, Miller AF. Thermo-Reversible Protein Fibrillar Hydrogels as Cell Scaffolds. Faraday Discussions 2008;139:71-84.

Helen W, Gough JE. Cell viability, proliferation and extracellular matrix production of human annulus fibrosus cells cultured within PDLLA/Bioglass(R) composite foam scaffolds in vitro. Acta Biomaterialia 2008;4:230-243.

Saunders R, Gough JE, Derby B. Delivery of human fibroblast cells by piezoelectric drop-on-demand inkjet printing. Biomaterials 2008;29(2):193-203.

Tissue engineering using ceramics and polymers. Eds: AR Boccaccini, JE Gough. Woodhead Publishing Ltd. 2008.

Gough JE, Christian P. Polycaprolactone. In: Encyclopedia of Biomaterials and Biomedical Engineering. 2nd Edition. Taylor and Francis, CRC Press 2008. Eds: GE Wnek, GL Bowlin.

2007

Todd SJ, Farrar D, Gough JE, Ulijn RV. Enzyme-triggered cell attachment to hydrogel surfaces. Soft Matter 2007;3(5):547-550.

Jayawarna V, Smith A, Gough JE and Ulijn RV. Three-dimensional cell culture of chondrocytes on modified di-phenylalanine scaffolds. Biochemical Society Transactions 2007;35(3):535?537.

Ulijn RV, Bibi N, Jayawarna V, Thornton PD, Todd SJ, Mart RJ, Smith AM, Gough JE. Bioresponsive hydrogels. Materials Today 2007;10(4):40-48.

Rawsterne RE, Todd SJ, Gough JE, Farrar D, Rutten FJM, Alexander MR, Ulijn RV. Cell Spreading Correlates with LogP on Amino Acid Surfaces. Acta Biomaterialia 2007;3(5):715-721.

Helen W, Gough JE. Three-dimensional culture of annulus fibrosus cells within PDLLA/Bioglass composite foam scaffolds: Assessment of cell attachment, proliferation and extracellular matrix production. Biomaterials 2007;28(11):2010-2020.

Guo X, Gough JE, Liu J, Shen Z, Xiao P. Fabrication of nanostructured hydroxyapatite and analysis of human osteoblastic cellular response. Journal of Biomedical Materials Research Part A 2007;82A(4):1022-1032

Guo X, Gough JE, Xiao P. Electrophoretic deposition of hydroxyapatite coating on Fecralloy and analysis of human osteoblastic cellular response. Journal of Biomedical Materials Research Part A 2007;80A(1):24-33.

2006

Rawsterne RE, Gough JE, Rutten FJM, Pham NT, Poon WC, Flitsch SL, Maltman B, Alexander MR, Ulijn RV. Controlling protein retention on enzyme-responsive surfaces. Surface and Interface Analysis 2006;38:1505-1511.

Yan H, Saiani A, Gough JE, Miller AF. Thermo-reversible protein hydrogel as cell scaffolds. Biomacromolecules 2006;7 (10):2776-2782.

Helen W, Gough JE. In vitro studies of annulus fibrosus disc cell attachment, differentiation and matrix production on PDLLA/45S5 Bioglass composite films. Biomaterials 2006;27(30):5220-5229.

Zourob M, Gough JE, Ulijn RV. A micro-patterned hydrogel platform for chemical synthesis and biological analysis. Advanced Materials 2006;18:655-659. Front cover

Jayawarna V, Ali M, Jowitt TA, Miller AF, Saiani A, Gough JE, Ulijn RV. Nano-structured hydrogels for 3D cell culture through self-assembly of Fmoc-dipeptides. Advanced Materials 2006;18:611-614.

2005

Jones JR, Vats A, Notingher I, Gough JE, Tolley NS, Polak JM, Hench LL. In situ monitoring of chondrocyte response to bioactive scaffolds using raman spectroscopy. Key Eng Mat 2005;284-286:623-626.

2004

Saunders R, Bosworth L, Gough J, Derby B, Reis N. Selective cell delivery for 3D tissue culture and engineering. European Cells and Materials 2004;7(Sup 1):84.

Milona M, Gough JE, Edgar AJ. Genomic structure and cloning of two transcript isoforms of human Sp8. BMC Genomics 2004;5:86.

Clupper DC, Hall MM, Gough JE, LaCourse WC, Hench LL. Bioactive evaluation of small diameter 45S5 bioactive glass fibres and preliminary study of human osteoblast attachment. J Mat Sci Mat Med 2004;15(7):803-808.

Gough JE, Clupper DC, Hench LL. Osteoblast responses to tape cast and sintered bioactive glass ceramics. J Biomed Mater Res 2004;69A(4):621-628.

Gough JE, Christian P, Unsworth J, Evans MP, Scotchford CA, Jones IA. Controlled degradation and macrophage responses of a fluoride treated polycaprolactone. J Biomed Mater Res 2004;69A:17-25.

Notingher I, Gough JE, Hench LL. Study of osteoblasts mineralisation in-vitro by Raman micro-spectroscopy. Key Eng Mat 2004;254-2:769-772.

Gough JE, Clupper DC, Hench LL. Osteoblast responses to sintered and tapecast bioactive glass. Key Eng Mat 2004;254-2:813-816.

Gough JE, Jones JR, Hench LL. Osteoblast nodule formation and mineralisation on foamed 58S bioactive glass. Key Eng Mat 2004;254-2:985-988.

Saravanapavan P, Gough JE, Hench LL. Antimicrobial macroporous gel-glasses: Dissolution and cytotoxicity. Key Eng Mat 2004;254-2:1087-1090.

Gough JE, Notingher I, Hench LL. Osteoblast attachment and mineralized nodule formation on rough and smooth 45S5 bioactive glass monoliths. J Biomed Mater Res 2004;68A(4): 640-650.

Gough JE, Jones JR, Hench LL. Nodule formation and mineralisation of human primary osteoblasts cultured on a porous bioactive glass scaffold. Biomaterials 2004;25(11): 2039-2046.

2003

Milona M, Gough JE, Edgar AJ. Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells. BMC Genomics 2003;4: art. no. 43 NOV 7

Blaker JJ, Gough JE, Maquet V, Notingher I, Boccaccini AR. In vitro evaluation of novel bioactive composites based on Bioglass (R)-filled polylactide foams for bone tissue engineering scaffolds. J Biomed Mater Res 2003;67A(4):1401-1411.

Gough JE, Christian P, Scotchford CA, Jones IA. Craniofacial osteoblast responses to polycaprolactone produced using a novel boron polymerisation technique and potassium fluoride post-treatment. Biomaterials 2003;24(27):4905-4912.

Clupper DC, Gough JE, Hall MM, Clare AG, LaCourse WC, Hench LL. In vitro bioactivity of S520 glass fibers and initial assessment of osteoblast attachment J Biomed Mater Res 2003;67A(1):285-294.

Gough JE, Christian P, Scotchford CA, Jones IA. Long-term craniofacial osteoblast culture on a sodium phosphate and a calcium/sodium phosphate glass. J Biomed Mater Res 2003;66A(2):233-240.

Gough JE, Arumugam M, Blaker J, Boccaccini AR. Bioglass (R) coated poly(DL-lactide) foams for tissue engineering scaffolds. Materialwiss Werkst 2003;34(7):654-661 .

Vats A, Tolley NS, Polak JM, Gough JE. Scaffolds and biomaterials for tissue engineering: a review of clinical applications. Clin Otolaryngol 2003;28(3):165-172.

2002

Roether JA, Gough JE, Boccaccini AR, Hench LL, Maquet V, Jerome R. Novel bioresorbable and bioactive composites based on bioactive glass and polylactide foams for bone tissue engineering. J Mater Sci-Mater M 2002;13(12):1207-1214.

Gough JE, Scotchford CA, Downes S. Cytotoxicity of glutaraldehyde crosslinked collagen/poly(vinyl alcohol) films is by the mechanism of apoptosis. J Biomed Mater Res 2002;61(1):121-130.

Gough JE, Christian P, Scotchford CA, Rudd CD, Jones IA. Synthesis, degradation, and in vitro cell responses of sodium phosphate glasses for craniofacial bone repair J Biomed Mater Res 2002;59(3):481-489.

2001

Gough JE, Downes S. Osteoblast cell death on methacrylate polymers involves apoptosis. J Biomed Mater Res 2001:57(4):497-505.


Last updated March 2020