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AFM image of nanofibrous gel SEM image of cell on glass Fluorescence image of fibroblasts in nanofibrous gel Fluorescence image of cell on fibre Fluorescence image of cell on glass Group photo 2014

Introduction

Our research is concerned with mechanically responsive connective tissues such as bone, muscle, cartilage and the intervertebral disc, novel 3-D scaffolds, self-assembling peptide hydrogels and directed cell responses using defined surfaces. We have been funded by EPSRC, BBSRC, MRC, UKRMP, DTI, NIHR i4i, Wellcome Trust, Leverhulme Trust, Royal Society, Royal Academy of Engineering, Johnson and Johnson, Smith and Nephew, Magnesium Elektron, Glycomar and the medical charity BackCare.

Latest Publications

Thaitalay P, Thongsri O, Dangviriyakul R, Carney L, Gough J, Rattanchan S. Primary human osteoblast and mesenchymal stem cell responses to apatite/tricalcium phosphate bone cement modified with polyacrylic acid and bioactive glass. In press: Journal of Biomedical Materials Research Part A. 2023.

Silva J, Spiess R, Marchesi A, Flitsch SL, Gough JE, Webb SJ. Enzymatic elaboration of oxime-linked glycoconjugates in solution and on liposomes. Journal of Materials Chemistry B, 2022;10 (26): 5016-5027.

Magaz A, Li X, Gough JE, Blaker JJ. Graphene oxide and electroactive reduced graphene oxide-based composite fibrous scaffolds for engineering excitable nerve tissue. Materials Science & Engineering C, 2021; 119. https://doi.org/10.1016/j.msec.2020.111632

Magaz A, Spencer BF, Hardy JG, Li X, Gough JE, Blaker JJ. Modulation of neuronal cell affinity on PEDOT–PSS non-woven silk scaffolds for neural tissue engineering. ACS Biomaterials Science & Engineering, 2020; 6 (12):6906-6916. DOI: 10.1021/acsbiomaterials.0c01239

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Last updated June 2025