Liver

The potential of tissue engineering

Porous foams

A sugar-derivatized porous network for hepatocyte culture

  • Polystyrene foams derivatized with lactose and heparin
  • Rat hepatocytes attached and maintained differentiated phenotype
  • Rounded cellular morphology with many microvilli
  • Increase in albumin secretion
  • Production of cytochrome P450-dependent metabolites

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