Liver
The potential of tissue engineering
Porous foams
Collagen
- Pores of 10um caused hepatocytes to be compact and cuboidal
- Albumin secretion 40pg/cell/day
- Positive vinculin staining
- Pores of 18um caused cells to be more spread
- Albumin decreased to 4pg/cell/day
- Pores of 82um caused an extensive 3-d cellular network
- Albumin secretion of 26pg/cell/day
- Positive E-cadherin staining
Image obtained from Ranucci et al, Biomaterials 21 (2000) 783-793
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Useful Links:
Lectures:
- Year 1:
- Cell Biology
- Year 2:
- Tissue Interactions and Biocompatibility
- Year 3/4:
- Tissue Engineering