Biomaterials and Tissue Engineering Group Dr Julie Gough

Research Areas

All my research falls into the field of tissue engineering of mechanically responsive connective tissues, cell responses to biomaterials and model surfaces.

Research areas include bone, cartilage, intervertebral disc, ligament and tendon tissue engineering. I also research macrophage responses to biomaterials and model substrates and engineering cell responses to surfaces.

Biomaterials

Bioactive glasses: monoliths, porous foams and fibres:

Degradable polymer/ceramic composites: PDLLA with bioactive glasses, LG112 glass with PEG.

Nano-scale hydroxyapatite coatings for orthopaedic applications with: Dr Ping Xiao.

Novel alloys for biomedical applications. Funded by EPSRC.

Tissue Engineering

Bone: Bioactive glass fibre scaffolds. Funded by DTI

Intervertebral disc: with Dr Judith Hoyland, University of Manchester. Funded by BackCare

Cartilage: Self-assembled peptide hydrogels with with: Dr Rein Ulijn. Funded by: EPSRC

Skin:

1. Fibrous cellulose scaffolds with: Dr Steve Eichhorn, Dr Rein Ulijn, Dr Bill Sampson. Funded by: EPSRC
2. Self assembled peptide hydrogels with: Dr Rein Ulijn. Funded by: Johnson and Johnson

Cells and Surfaces

Osteoblast and macrophage responses to a variety of surfaces and scaffolds.

Dynamic cell adhesion using enzyme responsive hydrogels with: Dr Rein Ulijn. Funded by: The Leverhulme Trust

Anti-inflammatory surfaces using enzyme responsive hydrogels with: Dr Rein Ulijn. Funded by: EPSRC and Smith and Nephew.