Peripheral Nerve

Stem cells

  • Neural stem cell isolation and culture in 1992
  • Have capacity to diff into mature neurons in vitro and in vivo
  • Accessibility an issue
  • Bone marrow stromal cells more easily available
  • MSCs express markers of neural progenitors including
    • Neurofilament proteins
    • Neuron specific nuclear protein
    • β-tubulin III
    • Glial fibrillary acidic protein
  • Can diff into neurons and glia

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