Peripheral Nerve
Synthetic conduits
- Silicone
- Non absorbable inert conduit
- Acts as a biological chamber allowing accumulation of GFs, ECM molecules and SCs
- Polyhydroxybutyrate
- Can be processed into resorbable mats that are strong, flexible and easy to handle making it suitable to use as a wrap around in direct nerve repair
- Conduits made from these mats promote axonal regeneration
- Can orientate the fibres providing directional and contact guidance to the regrowing axons
- Vascularisation has been shown
