Liver
The potential of tissue engineering
Encapsulation
Galactosylated alginate as a scaffold for hepatocyte entrapment
- Galactose moieties covalently coupled with alginate to polystyrene
- Adhesion of hepatocytes showed 18 fold increase compared to alginate alone
- Less spreading observed on GA modified surfaces
- Promotes cell-cell interactions
- Entrapment in GA/calcium capsules
- Higher cell viability
- More spheroid formation
- Albumin and urea secretion
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Useful Links:
Lectures:
- Year 1:
- Cell Biology
- Year 2:
- Tissue Interactions and Biocompatibility
- Year 3/4:
- Tissue Engineering