Skin

Dermal substitutes

  • Alloderm
    • Treated cadaver skin to remove antigenic epidermal cellular elements
    • Used on its own or with cultured autologous keratinocytes
  • Collagen and chondroitin 6 sulphate
    • Plus an outer silicone covering to prevent water loss
    • Protein and proteoglycan component degrades
    • Silicone sheet removed and covered with an autograft
    • Successful in burns and is FDA approved
  • Trancyte
    • Fibroblasts embedded in an inner nylon mesh
    • Additional silicone outer layer
    • Temporary measure in burn treatment
    • FDA approved

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