ML2921: Tissue Interactions and Biocompatibility

Cell and tissue damage

Fatty change - Liver

  • Mild accumulation may not affect gross appearance
  • Progressive accumulation - enlarges, yellows, can weigh up to 3-6kg
  • Typically occurs in alcoholism
  • Becomes enormously enlarged and leads to fibrosis - cirrhosis
  • Can return to normal before cirrhosis if revert to alcohol free diet

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