ML2921: Tissue Interactions and Biocompatibility

Cell and tissue damage

Ischemic and Hypoxic Injury

Reversible Cell Injury - Morphology

  1. Cellular swelling
    • First manifestation of all forms of injury
    • As water accumulates, vacuoles appear within cytoplasm
  2. Fatty change
    • Occurs in cells involved in and dependent upon fat metabolism e.g. hepatocytes and myocardial cells

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