Haemocompatibility and thrombogenicity
Thrombogenesis
Injury to endothelium
- Haemodynamic stress in hypertension
- Turbulent flow in arterial disorders
- Radiation injury
- Chemical agents of exogenous origin e.g. cigarette smoke
- Endogenous origin eg hypercholesterolemia, homocysteine
- Bacterial toxins
- Immunologic injuries e.g. transplant rejection, immune complex deposition