AFM image of nanofibrous gel SEM image of cell on glass Fluorescence image of fibroblasts in nanofibrous gel Fluorescence image of cell on fibre Fluorescence image of cell on glass Group photo 2014


Our research is concerned with mechanically responsive connective tissues such as bone, muscle, cartilage and the intervertebral disc, novel 3-D scaffolds and directed cell responses using defined surfaces. We have been funded by EPSRC, BBSRC, MRC, UKRMP, DTI, i4i, Leverhulme Trust, Royal Society, Royal Academy of Engineering, Johnson and Johnson, Smith and Nephew, Magnesium Elektron, Glycomar and the medical charity BackCare.

Latest Publications

Zarate-Trivino DG, Pool H, Vergara-Castaneda H, Elizalde-Pena EA, Vallejo-Becerra V, Villasenor F, Prokhorov E, Julie Gough, Garcia-Gaitan B, Luna-Barcenas G. Chitosan-g-glycidyl methacrylate-collagen II scaffold for cartilage regeneration. International Journal of Polymeric Materials and Polymeric Biomaterials 2019.

Zhou F-L, Wu H, McHugh DJ, Wimpenny I, Zhang X, Gough JE, Hubbard Cristinacce PL, Parker GJM. Co-electrospraying of tumour cell mimicking hollow polymeric microspheres for diffusion magnetic resonance imaging. Materials Science and Engineering:C 2019:101;217-227.

Magaz A, Faroni A, Gough JE, Reid AJ, Li X, Blaker J. Bioactive silk-based nerve guidance conduits for augmenting peripheral nerve repair. Advanced Healthcare Materials 2018;7(23).

Craven FL, Silva J, Segarra-Maset MD, Huang K, Both P, Gough JE, Flitsch SL, Webb SJ. "One-pot" sequential enzymatic modification of synthetic glycolipids in vesicle membranes. Chemical Communications 2018;54:1347-1350.

Wang QG, Wimpenny I, Dey RE, Zhong X, Youle PJ, Downes S, Watts DC, Budd PM, Hoyland JA, Gough JE. The unique calcium chelation property of poly(vinyl phosphonic acid-co-acrylic acid) and effects on osteogenesis in vitro. Journal of Biomedical Materials Research Part A 2018;106(1).

Latest News

Last updated March 2020