The Amaya Lab

Cranial nerves revealed in transgenic tadpole

Research in Molecular Embryology

A brief summary of our research directions:

FGF receptor signaling in early development

One of the main interests of our group is understanding the molecular events responsible for mesoderm formation and patterning. In particular we are investigating the role of fibroblast growth factor (FGF) signalling during mesoderm formation in the frog, Xenopus. More...

Functional genomics in Xenopus tropicalis

In order to identify additional genes involved in mesoderm specification and morphogenesis, we have been developing genomic resources and bioinformatics tools, in combination with functional screens, to identify additional genes involved in these processes. More...

Patterning of the nervous system

We are investigating the molecular basis of neural patterning in Xenopus. In a recent large scale functional screen we identified a novel D-type cyclin, which is essential for the specification and maintenance of the precursors of motor neurons (pMNs) within the spinal chord in Xenopus. More...

The molecular and cellular basis of tissue repair and regeneration

Amphibian embryos have an incredible ability to heal following manipulations, which is one of the primary reasons why they have been used for more than a century as an experimental embryological system. Xenopus embryos are able to heal following wounding within hours, without leaving a scar or any sign of damage. More...

GFP transgenic tadpole
Trigeminal nerve revealed in transgenic tadpole
CXEXGFP3 transgenic tadpole