The cytoskeleton

Stabilisation/Destabilisation

  • Proteins that bind along the sides of the polymer filament can alter stability and mechanical properties

  • Filament associated proteins use their binding energy to lower or raise the free energy of the polymer state, causing stabilisation or destabilisation

  • Microtubule associated proteins (MAPs)

  • Tropomyosin stabilise actin

  • Cofilin destabilises actin


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