The cytoskeleton

Elongation

  • Once nucleation has occured, elongation begins
  • Soluble monomer concentration is kept to 50-200uM
  • Proteins sequester subunits
  • Thymosin for actin
  • Stathmin for tubulin
  • Profilin releases actin subunits for polymerisation
  • Phosphorylation inhibits stathmin binding

Prev
Index
Next