Cell Death

Apoptosis

Genes

Apoptosis promoting/apoptosis inhibiting

• Promoting:
1. Ced-3 = ICE (interleukin-1β converting enzyme)
2. Ced-4 = APAF-1
3. p53
4. Bax
5. C-myc
6. Bad
• Inhibiting:
1. Ced-9 = Bcl-2
2. Inhibitor of apoptosis family (IAP)

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