Pathogens 3: Parasites

Neutrophils


Similar to macrophages

  • Phagocytic
  • Oxygen dependent
  • Oxygen independent
  • Intracellular destruction via granules - cytotoxic proteins
  • Extracellular destruction via H2O2
  • ADCC to kill larvae of S. Mansoni
When neutrophils attack a large parasite they "mob" and dismember the organism
When a neutrophil makes contact with a virulent Entamoeba the neutrophil dies by apoptosis
Video taken from www.cellsalive.com
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