Pathogens 2: Bacteria
Intracellular Bacteria
- Survive and replication inside phagocytic cells
- Sometimes within other host cells
- Evasion mechanisms
- Bacterial proteins become processed and presented
- T cell responses
- Th1 (CD4) secrete interleukins therefore activating the infected phagocytes
- Converted from habitat to an effector cell
- Cytotoxic T cells
- Lysis allows other phagocytes to act, increasing the response
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Lectures:
- Year 1:
- Cell Biology
- Year 2:
- Tissue Interactions and Biocompatibility
- Year 3/4:
- Tissue Engineering