Haemocompatibility and thrombogenicity
Heparin releasing systems
Electric current is used to rapidly change the structural arrangement of an electroerodible polyelectrolyte complex (heparin + +vely charged polymer)
- Polymer matrix dissolves in proportion to the intensity of the electric current
- Current produces hydroxyl ions near cathode
- Increases local pH
- Disrupts ionic bonds of polymer
- Releases heparin from surface
- Alter pattern of current --> control release
| Prev | Next |
Useful Links:
Lectures:
- Year 1:
- Cell Biology
- Year 2:
- Tissue Interactions and Biocompatibility
- Year 3/4:
- Tissue Engineering