2023

A GWAS meta-analysis of alpha angle suggests cam-type morphology may be a specific feature of hip osteoarthritis in older adults   

B. Faber, M. Frysz, A. Hartley, R. Ebsim, C. Boer, F. Saunders, J. Gregory, R. Aspden, N. Harvey, L Southam, W. Giles, C. Le Maitre, M. Wilkinson, J. Van Moers, E. Zeggini, T. Cootes, C. Lindner, J. Kemp, G. Davey Smith and J. Tobias.

Arthritis and Rheumatology, 2023. doi:10.1002/art.42451

Shape and texture features in normal appearing radiographs as predictors of subsequent Charcot foot    

M. deSancha, T. Cootes, C. Lindner, J. Harris, F. Bowling and A. Pillai.

Proceedings of the 9th International Symposium on the Diabetic Foot (ISDF 2023), 2023. To appear. (Abstract) [Talk]

Automatically Measuring Paediatric Hip Radiographs in Cases of Cerebral Palsy     

P. Thompson, M. Khattak, D. C. Perry, Medical Annotation Collaborative, T. F. Cootes and C. Lindner.

British Society for Children’s Orthopaedic Surgery Annual Meeting, 2023. To appear. (Abstract) [Talk]

A novel polygenic risk score for femoral neck width predicts hip fracture      

M. Frysz, M. Nethander, R. Ebsim, T. Cootes, C. Lindner, F.R. Saunders, J.S. Gregory, R.M. Aspden, N.C. Harvey, B.G. Faber, J.H. Tobias and C. Ohlsson.

Proceedings of the 2023 European Calcified Tissue Society Annual Meeting (ECTS 2023), 2023. To appear. (Abstract) [Talk]

Deep Learning Framework Improves Wound Histology Analysis by Accurately Segmenting Multiple Important Tissue Types       

C.J. Robinson, C. Lindner, T. Cootes and S. Kurinna.

Proceedings of the 18th European Molecular Imaging Meeting (EMIM 2023), 2023. To appear. (Abstract) [Talk]

The association between statistical shape variations of the hip and the development of radiographic hip osteoarthritis within 8 years of follow-up: data from 17,738 hips in the World COACH Consortium         

M.M.A. van Buuren, F. Boel, N.S. Riedstra, H. Ahedi, V. Arbabi, N. Arden, S.M.A. Bierma-Zeinstra, C.G. Boer, F.M. Cicuttini, T.F. Cootes, D.T. Felson, W.P. Gielis, G. Jones, S. Kluzek, N.E. Lane, C. Lindner, J. Lynch, J. van Meurs, A.E. Nelson, M.C. Nevitt, E.H. Oei, J. Runhaar, T.D. Spector, J. Tang, H. Weinans and R. Agricola.

Proceedings of the 2023 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2023). To appear. (Abstract) [Talk]

Triradiate cartilage orientation is associated with acetabular dysplasia in 9 year olds        

F. Boel, D. Chen, S. de Vos-Jakobs, N.S. Riedstra, C. Lindner, J.J. Tolk,  J. Runhaar, S.M.A. Bierma-Zeinstra and R. Agricola.

Proceedings of the 2023 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2023). To appear. (Abstract) [Poster]

Acetabular dysplasia is a risk factor for developing radiographic hip osteoarthritis; data from the World COACH consortium         

N.S. Riedstra , F. Boel, M.M.A. van Buuren, H. Ahedi, V. Arbabi, N. Arden, S.M.A. Bierma-Zeinstra, C.G. Boer, F.M. Cicuttini, T.F. Cootes, D.T. Felson, W.P. Gielis, G. Jones, S. Kluzek, N.E. Lane, C. Lindner, J. Lynch, J. van Meurs, A.E. Nelson, M.C. Nevitt, E.H. Oei, J. Runhaar, T.D. Spector, J. Tang, H. Weinans and R. Agricola.

Proceedings of the 2023 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2023). To appear. (Abstract) [Poster]

Pincer morphology is a risk factor for developing radiographic hip osteoarthritis; data from the World COACH consortium         

N.S. Riedstra , M.M.A. van Buuren, F. Boel, H. Ahedi, V. Arbabi, N. Arden, S.M.A. Bierma-Zeinstra, C.G. Boer, F.M. Cicuttini, T.F. Cootes, D.T. Felson, W.P. Gielis, G. Jones, S. Kluzec, N.E. Lane, C. Lindner, J. Lynch, J. van Meurs, A.E. Nelson, M.C. Nevitt, E.H. Oei, J. Runhaar, T.D. Spector, J. Tang, H. Weinans and R. Agricola.

Proceedings of the 2023 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2023). To appear. (Abstract) [Poster]

Hip geometric parameters are associated with radiographic and clinical hip osteoarthritis: findings from a cross-sectional study in UK Biobank          

S.V. Heppenstall, R. Ebsim, F.R. Saunders, C. Lindner, J.S. Gregory, N.C. Harvey, T. Cootes, J.H. Tobias, M. Frysz and B.G. Faber.

Proceedings of the 2023 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2023). To appear. (Abstract) [Poster]

2022

Achieving GM's ambitions in Health Innovation 

C. Lindner.

Invited panel member at pro-manchester Health Tech Conference 2022, Manchester, UK, December 2022.

Applications of AI to Study, Diagnose and Manage Musculoskeletal Disorders 

C. Lindner.

Invited keynote talk at 4th International Conference on Medical Imaging & Therapeutics (MIT-2022), USA, Online, December 2022.

Computer-aided analysis of radiographic imaging data to study, diagnose and manage musculoskeletal disorders 

C. Lindner.

Invited talk at IMechE Biomedical Engineering Division Annual Orthopaedics Meeting 2022, UK, Online, November 2022.

High bone mass and cam morphology are independently related to hip osteoarthritis: findings from the High Bone Mass Study   

B.E. Zucker, R. Ebsim, C. Lindner, S. Hardcastle, T. Cootes, J.H. Tobias, M.R. Whitehouse, C.L. Gregson, B. G. Faber and A. Hartley.

BMC Musculoskeletal Disorders, Vol. 23, No. 757 , 2022. doi:10.1186/s12891-022-05603-3   

Machine-learning derived acetabular dysplasia and cam morphology are features of severe hip osteoarthritis: findings from UK Biobank  

M. Frysz, B. Faber, R. Ebsim, F. Saunders, C. Lindner, J. Gregory, R. Aspden, N. Harvey, T. Cootes and J. Tobias.

Journal of Bone and Mineral Research, 2022. doi:10.1002/jbmr.4649  

A software system to automatically assess hip migration in children with Cerebral Palsy  

P. Thompson, Medical Annotation Collaborative, D.C. Perry, T.F. Cootes and C.Lindner.
AI in Orthopaedics Conference, Orthopaedic Research UK, 2022. (Abstract) [Talk]

The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study   

M. M. A. van Buuren, J. J. Heerey, A. Smith, K. M. Crossley, J. L. Kemp, M. J. Scholes, P. R. Lawrenson, M. G. King, W. P. Gielis, H. Weinans, C. Lindner, R.B. Souza, J.A.N. Verhaar and R. Agricola.

Osteoarthritis and Cartilage Open, 2022. doi:10.1016/j.ocarto.2022.100275   

Automation of clinical measurements on radiographs of children's hips 

P. Thompson, Medical Student Annotation Collaborative, D.C. Perry, T.F. Cootes and C. Lindner.
Proceedings of the 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022), Singapore. Springer, Lecture Notes in Computer Science 13433, pages 419-428, 2022. doi:
10.1007/978-3-031-16437-8_40 (Full Paper) [Poster]

Automatic Segmentation of Hip Osteophytes in DXA Scans using U-Nets

R. Ebsim, B. Faber, F. Saunders, M. Frysz, J. Gregory, N. Harvey, J. Tobias, C. Lindner and T. Cootes.
Proceedings of the 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022), Singapore. Springer, Lecture Notes in Computer Science 13435, pages 3-12, 2022. doi:
10.1007/978-3-031-16443-9_1 (Full Paper) [Poster]

Cam morphology does not appear to cause osteoarthritis: findings from a Mendelian randomisation study 

B. Faber, M. Frysz, A. Hartley, C. Boer, R. Ebsim, L Southam, F. Saunders, J. Gregory, N. Harvey, J. Van Moers, E. Zeggini, T. Cootes, C. Lindner, J. Kemp, G. Davey Smith and J. Tobias.
Proceedings of the Bone Research Society Annual Meeting 2022. To appear. (Abstract) [Talk]

Describing the genetic architecture of hip shape: findings from UK Biobank  

M. Frysz, B. Faber, R. Ebsim, F. Saunders, J. Gregory, N. Harvey, C. Lindner, T. Cootes, J. Kemp and J. Tobias.
Proceedings of the Bone Research Society Annual Meeting 2022. To appear. (Abstract) [Talk]

Describing the genetic architecture of minimum joint space width at the hip joint  

B. Faber, M. Frysz, C. Boer, D. Evans, R. Ebsim, K. Flynn, M. Lundberg, L Southam, A. Hartley, F. Saunders, C. Lindner, J. Gregory, R. Aspden, N. Lane, N. Harvey, E. Zeggini, G. Davey Smith, T. Cootes, J. Van Moers, J. Kemp and J. Tobias.
Proceedings of the Bone Research Society Annual Meeting 2022. To appear. (Abstract) [Poster]

The association between hip geometry and hip osteoarthritis: findings from 40,000 UK Biobank participants  

S. Heppenstall, R. Ebsim, F. Saunders, C. Lindner, J. Gregory, N. Harvey, T. Cootes, J. Tobias, M. Frysz, B. Faber.
Proceedings of the Bone Research Society Annual Meeting 2022. To appear. (Abstract) [Poster]

A genome wide association study of DXA-derived minimum joint space width of the hip provides further insights into its genetic architecture: findings from UK Biobank

B.G. Faber, M. Frysz, R. Ebsim, M. Lundberg, L. Southam, A. Hartley, F.R. Saunders, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, E. Zeggini, G. Davey Smith, T. Cootes, J.P. Kemp and J.H. Tobias.

Proceedings of the 2022 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2022). Osteoarthritis and Cartilage, Vol. 30, Suppl. 1, pages S47-S48, 2022. doi:10.1016/j.joca.2022.02.051 (Abstract) [Talk]

Cam morphology is not causally associated with hip osteoarthritis: findings from a Mendelian randomisation study

B.G. Faber, M. Frysz, A. Hartley, R. Ebsim, F.R. Saunders, J.S. Gregory, N.C. Harvey, E. Zeggini, T. Cootes, C. Lindner, J.P. Kemp, G. Davey Smith and J.H. Tobias.

Proceedings of the 2022 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2022). Osteoarthritis and Cartilage, Vol. 30, Suppl. 1, pages S336-337, 2022. doi:10.1016/j.joca.2022.02.452 (Abstract) [Poster]

Acetabular dysplasia and cam morphology are features of severe hip osteoarthritis: findings from a cross-sectional study in UK Biobank

M. Frysz, B. Faber, R. Ebsim, F. Saunders, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, T. Cootes and J.H. Tobias.

Proceedings of the 2022 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2022). Osteoarthritis and Cartilage, Vol. 30, Suppl. 1, pages S278, 2022. doi:10.1016/j.joca.2022.02.375 (Abstract) [Poster]

The Worldwide Collaboration on OsteoArthritis prediCtion for the Hip (World COACH) consortium: design and rationale of a consortium using individual participant data from prospective cohort studies

M.M.A. van Buuren, H. Ahedi, V. Arbabi, N. Arden, S.M.A. Bierma-Zeinstra, C.G. Boer, F.M. Cicuttini, T.F. Cootes, D.T. Felson, W.P. Gielis, G. Jones, N.E. Lane, C. Lindner, J. Lynch, J. van Meurs, A.E. Nelson, M.C. Nevitt, E.H. Oei, N.S. Riedstra, J. Runhaar, T. Spector, J. Tang, H. Weinans, R. Agricola.

Proceedings of the 2022 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2022). Osteoarthritis and Cartilage, Vol. 30, Suppl. 1, pages S253-S254, 2022. doi:10.1016/j.joca.2022.02.345 (Abstract) [Poster]

Segmentation of Multiple Tissue Types in Regenerating Wounds

C.J. Robinson, C. Lindner, S. Kurinna and T. Cootes.

Proceedings of the 17th European Molecular Imaging Meeting (EMIM 2022). (Abstract) [Poster]

A novel semi-automated classifier of hip osteoarthritis on DXA images shows expected relationships with clinical outcomes in UK Biobank

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes and J.H. Tobias.

Rheumatology, 2022. doi:10.1093/rheumatology/keab927

Radiographic hip osteoarthritis classified semi-automatically on dual-energy x-ray absorptiometry scans is strongly predictive of total hip replacement: findings from UK Biobank

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes and J.H. Tobias.

Proceedings of the 2022 British Society of Rheumatology Annual Conference. Rheumatology, Vol. 61, Suppl. 1, keac132.020, 2022. doi:10.1093/rheumatology/keac132.020 (Abstract) [Talk]

A Fully Automatic System to Assess Foot Collapse on Lateral Weight-bearing Foot Radiographs: A Pilot Study

J. Lauder, J. Harris, B. Layton, P. Heire, A. Sorani, M. DeSancha, A.K. Davison, C. Sammut-Powell and C. Lindner.

Computer Methods and Programs in Biomedicine, Vol. 213, No. 106507, 2022. doi:10.1016/j.cmpb.2021.106507

2021

Developing AI Software for Clinical Applications: An Automated System for Assessing Hip Diseases in Children

C. Lindner.

Invited talk at Translational Research at Manchester 2021, Manchester, UK, December 2021. [Talk]

Automated Analysis of Medical Images to Study, Diagnose and Manage Musculoskeletal Disorders

C. Lindner.

Invited talk at MSK Lab Seminar, Imperial College London, UK, November 2021. [Talk]

Cam morphology but neither acetabular dysplasia nor pincer morphology is associated with osteophytosis throughout the hip: findings from a cross-sectional study in UK Biobank

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes, C. Lindner and J.H. Tobias.

Osteoarthritis and Cartilage, Vol. 29, No. 11, pages 1521-1529, 2021. doi:10.1016/j.joca.2021.08.002 

Osteophyte size and location on hip DXA scans are associated with hip pain: Findings from a cross sectional study in UK Biobank

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes and J.H. Tobias.

Bone, Vol. 153, 2021. doi:10.1016/j.bone.2021.116146 

A novel semi-automated classifier of radiographic hip osteoarthritis on DXA scans is strongly predictive of pain, clinical diagnosis and joint replacement: findings from 40,000 participants in UK Biobank

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes and J.H. Tobias.

Proceedings of the 2021 American College of Rheumatology Annual Meeting (ACR Convergence 2021), Arthritis Rheumatology, 73 (suppl 10), 2021. (Abstract) [Talk]

Developing AI Software for Clinical Applications: Automated Bone Shape Analysis with BoneFinder®

C. Lindner.

Invited talk at Greater Manchester AI Foundry, Manchester, UK, September 2021. [Talk]

DXA-derived hip shape predicts total hip replacement: findings from UK Biobank

M. Frysz, B.G. Faber, R. Ebsim, F.R. Saunders, C. Lindner, J.S. Gregory, R.M. Aspden, N.C. Harvey, T. Cootes and J.H. Tobias.

Proceedings of the 2021 American Society of Bone and Mineral Research Annual Meeting (ASBMR 2021). To appear. (Abstract) [Poster]

BoneFinder®: a software tool to enable automated bone shape analyses

C. Lindner.

Invited talk at Medical Imaging Convention 2021, Birmingham, UK, September 2021. [Talk]

The Association Between Statistical Shape Variations of the Hip and the Presence of a Cartilage Defect or Labral Tear on MRI in High-Impact Athletes

M. M. A. van Buuren, J. J. Heerey, A. Smith, J. L. Kemp, M. J. Scholes, P. R. Lawrenson, M. G. King, W. P. Gielis, H. Weinans, C. Lindner, K. M. Crossley and R. Agricola.

Proceedings of the 2021 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2021). Osteoarthritis and Cartilage, Vol. 29, Suppl. 2, pages S25-S26, 2021. doi:10.1016/j.joca.2021.05.039  (Abstract) [Poster]

Deriving alpha angle from anterior-posterior dual-energy x-ray absorptiometry scans: an automated and validated approach [version 1; peer review: awaiting peer review]

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, G. Davey Smith, T. Cootes, J.H. Tobias and C. Lindner.

Wellcome Open Research, 2021. doi:10.12688/wellcomeopenres.16656.2

Osteophyte size and location on dual-energy X-ray absorptiometry scans is related to hip pain: findings from a cross sectional study in UK Biobank 

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes, C. Lindner and J.H. Tobias.

Proceedings of the 2021 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2021). Osteoarthritis and Cartilage, Vol. 29, Suppl. 1, page S44-45, 2021. doi:10.1016/j.joca.2021.02.065  (Abstract) [Talk]

Cam morphology is associated with radiographic hip osteoarthritis and hip pain in men but not in women: findings from a cross-sectional study in UK Biobank  

B.G. Faber, R. Ebsim, F.R. Saunders, M. Frysz, J.S. Gregory, R.M. Aspden, N.C. Harvey, G. Davey Smith, T. Cootes, C. Lindner and J.H. Tobias.

Proceedings of the 2021 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2021). Osteoarthritis and Cartilage, Vol. 29, Suppl. 1, page S291-292, 2021. doi:10.1016/j.joca.2021.02.385   (Abstract) [Poster]

Knee joint shape, osteophytes and knee pain: What’s the connection?  

F.R. Saunders, M. Frysz, A. Sarmanova, R. Ebsim, C. Lindner, J.S. Gregory, N.C. Harvey, R.M. Aspden, T. Cootes and J.H. Tobias.

Proceedings of the 2021 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2021). Osteoarthritis and Cartilage, Vol. 29, Suppl. 1, page S325-326, 2021. doi:10.1016/j.joca.2021.02.426  (Abstract) [Poster]

2020

Statistical Shape Modeling of the Hip and the Association with Hip Osteoarthritis: a Systematic Review

M.M.A. van Buuren, N.K. Arden, S.M.A. Bierma-Zeinstra, W.M. Bramer, N. Casartelli, D.T. Felson, G. Jones, N.E. Lane, C. Lindner, N.A. Maffiuletti, J.B.J. van Meurs, A.E. Nelson, M.C. Nevitt, P.L. Valenzuela, J.A.N. Verhaar, H. Weinans and R. Agricola.
Osteoarthritis and Cartilage, Vol. 29, No. 5, pages 607-618, 2021. doi:
10.1016/j.joca.2020.12.003

Predicting the mechanical Hip-Knee-Ankle angle accurately from standard knee radiographs, a cross-validation experiment in 100 patients

W.P. Gielis, H. Rayegan, V. Arbabi, S.Y.A. Brooghani, C. Lindner, T.F. Cootes, P.A. de Jong, H. Weinans and R.J.H. Custers.

Acta Orthopaedica, Vol. 91, No. 6, pages 732-737, 2020. doi:10.1080/17453674.2020.1779516 

Detecting Perthes Disease and Investigating the Effects of Aging on Hip Shape in Children

A.K. Davison, T.F. Cootes, D.C. Perry, W. Luo, Medical Student Annotation Collaborative and C. Lindner.

Proceedings of the Bone Research Society Annual Meeting 2020. Journal of Bone & Mineral Research Plus, Vol. 5, Art. Nr. e10499, page 63, 2021. doi:10.1002/jbm4.10499 (Abstract) [Virtual Poster] (Best Clinical Poster Prize)

Development of a machine learning-based fully automated hip annotation system for DXA scans

R. Ebsim, C. Lindner, B. Faber, M. Frysz, F. Saunders, J. Gregory, R. Aspden, J. Parkinson, N. Harvey, J. Tobias and T. Cootes.

Proceedings of the Bone Research Society Annual Meeting 2020. Journal of Bone & Mineral Research Plus, Vol. 5, Art. Nr. e10499, page 48, 2021. doi:10.1002/jbm4.10499 (Abstract) [Virtual Poster]

BoneFinder: Automatic Analysis of (Skeletal) Structures in X-ray Images

C. Lindner.

Invited talk at Henry Moseley X-Ray Imaging Facility (HMXIF) Seminar, Manchester, UK, July 2020. [Talk]

The association between adult hip morphology and hip osteoarthritis: a systematic review

M.M.A. van Buuren, N.K. Arden, S.M.A. Bierma-Zeinstra, W.M. Bramer, N. Casartelli, D.T. Felson, G. Jones, N.E. Lane, C. Lindner, N.A. Maffiuletti, J.B.J. van Meurs, A.E. Nelson, M.C. Nevitt, P.L. Valenzuela, J.A.N. Verhaar, H.H. Weinans and R. Agricola.

Proceedings of the 2020 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2020). Osteoarthritis and Cartilage, Vol. 28, Suppl. 1, page S260-261, 2020. doi:10.1016/j.joca.2020.02.420 (Abstract) [Poster]

An automated workflow based on hip shape improves personalized risk prediction for hip osteoarthritis in the CHECK study

W.P. Gielis, H.H. Weinans, P.M.J. Welsing, W.E. van Spil, R. Agricola, T. Cootes, P.A. de Jong and C. Lindner.

Osteoarthritis and Cartilage, Vol. 28, No. 1, pages 62-70, 2020. doi:10.1016/j.joca.2019.09.005

2019

A New Innovative Software to Automatically Outline Condyles In Orthopantomography

V.B. Krishnakumar Raja, B. Sasikala, P. Elavenil, R. Sethupathy Cheeman, T. Cootes and C. Lindner.

International Journal of Medical Science and Innovative Research, Vol. 4, No. 6, pages 123-134, 2019.    

Lessons from Musculoskeletal Research: Developing Software for Clinical Applications

C. Lindner.

Invited talk at UoM Translational Workshop in Respiratory Medicine, Wythenshawe Hospital, Manchester, UK, November 2019. [Talk]

Automated shape and appearance analyses of skeletal x-ray images

C. Lindner.

Invited talk at IMPC (International Mouse Phenotyping Consortium) Data Analysis Workshop, London, UK, July 2019. [Talk]

Automated estimation of the mechanical Hip-Knee-Ankle angle using standard knee radiographs

W. Gielis, H. Rayegan, V. Arbabi, S.Y. Ahmadi Brooghani, C. Lindner, T.F. Cootes, P.A. de Jong, H. Weinans and R. Custers.

Proceedings of the 2019 International Cartilage Regeneration & Joint Preservation Society World Congress (ICRS 2019), Vancouver, Canada. To appear. (Abstract) [Poster]

Changes in bone shape are both a risk factor for and a result of osteoarthritis, a follow-up study in the CHECK cohort

W. Gielis, H. Rayegan, C. Lindner, A. K. Davison, V. Arbabi, T.F. Cootes, P.A. de Jong and H. Weinans.

Proceedings of the 2019 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2019), Toronto, Canada. Osteoarthritis and Cartilage, Vol. 27, Suppl. 1, page S320-321, 2019. doi:10.1016/j.joca.2019.02.722 (Abstract) [Poster]

2018

Landmark Localisation in Radiographs Using Weighted Heatmap Displacement Voting

A.K. Davison, C. Lindner, D.C. Perry, W. Luo, Medical Student Annotation Collaborative and T.F. Cootes.

Proceedings of the 6th MICCAI Workshop on Computational Methods and Clinical Applications in Musculoskeletal Imaging (MSKI 2018), Granada, Spain. Springer-Verlag Lecture Notes in Computer Science 11404, pages 73-85, 2018. doi:10.1007/978-3-030-11166-3_7 (Full Paper) [Talk]

Perthes Disease Classification Using Shape and Appearance Modelling

A.K. Davison, T.F. Cootes, D.C. Perry, W. Luo, Medical Student Annotation Collaborative and C. Lindner.

Proceedings of the 6th MICCAI Workshop on Computational Methods and Clinical Applications in Musculoskeletal Imaging (MSKI 2018), Granada, Spain. Springer-Verlag Lecture Notes in Computer Science 11404, pages 86-98, 2018. doi:10.1007/978-3-030-11166-3_8 (Full Paper) [Talk]

Fully automatic teeth segmentation in adult OPG images

N. Vila Blanco, T. Cootes, C. Lindner, I. Tomás and M.J. Carreira.

Proceedings of the 6th MICCAI Workshop on Computational Methods and Clinical Applications in Musculoskeletal Imaging (MSKI 2018), Granada, Spain. Springer-Verlag Lecture Notes in Computer Science 11404, pages 11-21, 2018. doi:10.1007/978-3-030-11166-3_2 (Full Paper) [Talk]

2017

Shape and Texture Modeling of Hip Bone Density for Fracture Discrimination

J.A. Shepherd, A.P. Mahmoudzadeh, B. Fan, L. Chaplin, T. Cootes, J.A. Cauley, P. Cawthon, S. Cummings, F. Liu, C. Lindner, R. Murphy, M. Visser and A. Schwartz.

Proceedings of the 2017 Annual Meeting of the American Society for Bone and Mineral Research (ASBMR 2017), Colorado Convention Center, Denver, USA. Journal of Bone and Mineral Research, Vol. 32, page S178, 2017. doi:10.1002/jbmr.3363 (Abstract) [Poster]

Adaptable landmark localisation: applying model transfer learning to a shape model matching system

C. Lindner, D. Waring, B. Thiruvenkatachari, K. O'Brien and T. Cootes.
Proceedings of the 20th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2017), Quebec City, Quebec, Canada. Springer-Verlag Lecture Notes in Computer Science 10433, pages 144-151, 2017. (Full Paper) [Poster]

Automated Image Interpretation Using Statistical Shape Models

C. Lindner.
Chapter 1 in “Statistical Shape and Deformation Analysis: Methods, Implementation and Applications”,  G. Zheng, S. Li and G. Szekely, editors. Academic Press, pages 3-32, 2017. doi:
10.1016/B978-0-12-810493-4.00002-X

Automatic Annotation of Radiographs using Random Forest Regression Voting for Building Statistical Models for Skeletal Maturity

S.A. Adeshina, C. Lindner and T.F. Cootes.
International Journal of Computer Techniques, Vol. 4, No. 1, 2017.

Prediction of risk for radiographic hip osteoarthritis in subjects with early osteoarthritis of hip or knee

W.P. Gielis, H.H. Weinans, W.E. van Spil, T.F. Cootes, P.A. de Jong and C. Lindner.
Proceedings of the 2017 Osteoarthritis Research Society International World Congress on Osteoarthritis (OARSI 2017), Caesar's Palace, Las Vegas, USA. Osteoarthritis and Cartilage, Vol. 25, Suppl. 1, page S12, 2017. doi:
10.1016/j.joca.2017.02.036 (Abstract) [Talk]

2016

New software to automatically outline bones in OPG

B. Sasikala, V.B. Krishnakumar Raja, T.F. Cootes and C. Lindner.
Proceedings of the 41st Annual Congress of Association of Oral and Maxillofacial Surgeons of India (AOMSI 2016), Gujarat, India. Congress Handbook, page 167, OP-TM7, 2016. (Abstract) [Talk]

Fully Automatic System for Accurate Localisation and Analysis of Cephalometric Landmarks in Lateral Cephalograms

C. Lindner, C-W. Wang, C-T. Huang, C-H. Li, S-W. Chang and T. Cootes.
Scientific Reports, Vol. 6, Art. Nr. 33581, 2016. doi:
10.1038/srep33581 

Multi-point Regression Voting for Shape Model Matching

P.A. Bromiley, C. Lindner, J. Thomson, M. Wrigley and T.F. Cootes.
Proceedings of the 20th International Conference On Medical Imaging Understanding and Analysis (MIUA) 2016, Loughborough, UK, 2016. Elsevier Procedia Computer Science, Vol. 90, pages 48-53, 2016. doi:10.1016/j.procs.2016.07.009 (Full Paper) [Talk]

Fully automated radiographic knee shape analysis of the OAI dataset: Is knee shape asymmetry an early indicator of unilateral knee OA?

C. Lindner and T.F. Cootes.
Proceedings of the 9th International Workshop on Osteoarthritis Imaging (IWOAI) 2016, Oulu, Finland. Workshop Handbook, page 57, 2016. www.iwoai.org/iwoai-workshops (Abstract) [Poster]

A benchmark for comparison of dental radiography analysis algorithms

C.-W. Wang, C.-T. Huang, J.-H. Lee, C.-H. Li, S.-W. Chang, M.-J. Siao, T.-M. Lai, B. Ibragimov, T. Vrtovec, O. Ronneberger, P. Fischer, T.F. Cootes and C. Lindner.
Medical Image Analysis, Vol. 31, pages 63-76, 2016. doi:
10.1016/j.media.2016.02.004

2015

BoneFinder: Automated Bone Shape and Appearance Analysis in 2D Radiographs

C. Lindner.
Invited talk at Berliner Colloquium für Wissenschaftliche Visualisierung, Konrad-Zuse-Zentrum für Informationstechnik Berlin (ZIB), Berlin, Germany. November, 2015. [Talk]

Learning-based Shape Model Matching: Training Accurate Models with Minimal Manual Input

C. Lindner, J. Thomson, The arcOGEN Consortium and T.F. Cootes.
Proceedings of the 18th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2015, Part III), Munich, Germany. Springer-Verlag Lecture Notes in Computer Science 9351, pages 580-587, 2015. (Full Paper) [Poster]

Cake-cutting: Fair Division of Divisible Goods

C. Lindner and J. Rothe.
Chapter 7 in “Economics and Computation: An Introduction to Algorithmic Game Theory, Computational Social Choice, and Fair Division”, J. Rothe, editor. Springer-Verlag Berlin Heidelberg, pages 393-491, 2015.

Investigation of Association between Hip Osteoarthritis Susceptibility Loci and Radiographic Proximal Femur Shape

C. Lindner, S. Thiagarajah, J.M. Wilkinson, K. Panoutsopoulou, A.G. Day-Williams, The arcOGEN Consortium, T.F. Cootes and G.A. Wallis.
Arthritis & Rheumatology, Vol. 67, No. 8, pages 2076-2084, 2015. doi:10.1002/art.39186

Fully Automatic Cephalometric Evaluation using Random Forest Regression-Voting

C. Lindner and T.F. Cootes.
Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI) 2015 – Grand Challenges in Dental X-ray Image Analysis – Automated Detection and Analysis for Diagnosis in Cephalometric X-ray Image, New York, USA, 2015. (Full Paper) [Talk] [1st Prize]

2014

Robust and Accurate Shape Model Matching using Random Forest Regression-Voting

C. Lindner, P.A. Bromiley, M.C. Ionita and T.F. Cootes.
IEEE Transactions on Pattern Analysis and Machine Intelligence, Vol. 37, No. 9, pages 1862-1874, 2015. doi:10.1109/TPAMI.2014.2382106

Automatic segmentation of carpal area bones with random forest regression voting for estimating skeletal maturity in infants

S.A. Adeshina, C. Lindner and T.F. Cootes.
Proceedings of the 11th International Conference on Electronics, Computer and Computation (ICECCO 2014), Abuja, Nigeria. doi:
10.1109/ICECCO.2014.6997559 (Full Paper)

Automatic Extraction of Hand-Bone Shapes using Random Forest Regression-Voting in the Constrained Local Model Framework

C. Lindner and T.F. Cootes.
Proceedings of the 1st International Symposium on Statistical Shape Models (SHAPE 2014), Delmont, Switzerland. Congress Handbook, page 17, 2014. (Extended Abstract) [Talk]

Increasing Shape Modelling Accuracy by Adjusting for Subject Positioning: An Application to the Analysis of Radiographic Proximal Femur Symmetry using Data from the Osteoarthritis Initiative

C. Lindner, G.A. Wallis and T.F. Cootes.
Bone, Vol. 61, pages 64-70, 2014. doi:
10.1016/j.bone.2014.01.003

2013

Development of a Fully Automatic Shape Model Matching (FASMM) System to Derive Statistical Shape Models from Radiographs: Application to the Accurate Capture and Global Representation of Proximal Femur Shape

C. Lindner, S. Thiagarajah, J.M. Wilkinson, arcOGEN Consortium, G.A. Wallis and T.F. Cootes.
Osteoarthritis and Cartilage, Vol. 21, No. 10, pages 1537-1544, 2013. doi:
10.1016/j.joca.2013.08.008

Analysis of Proximal Femur Symmetry using Statistical Shape Models based on Data from the Osteoarthritis Initiative

C. Lindner, G.A. Wallis and T.F. Cootes.
Proceedings of the Bone Research Society & British Orthopaedic Research Society Joint Annual Meeting 2013, Oxford. The Bone and Joint Journal. To appear. (Abstract) [Talk]

Accurate Bone Segmentation in 2D Radiographs using Fully Automatic Shape Model Matching based on Regression-Voting

C. Lindner, S. Thiagarajah, J.M. Wilkinson, arcOGEN Consortium, G.A. Wallis and T.F. Cootes.
Proceedings of the 16th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2013, Part II), Nagoya, Japan. Springer-Verlag Lecture Notes in Computer Science 8150, pages 181-189, 2013. (Full Paper) [Poster]

Fully Automatic Segmentation of the Proximal Femur using Random Forest Regression Voting

C. Lindner, S. Thiagarajah, J.M. Wilkinson, arcOGEN Consortium, G.A. Wallis and T.F. Cootes.
IEEE Transactions on Medical Imaging,
Vol. 32, No. 8, pages 1462-1472, 2013. doi:10.1109/TMI.2013.2258030

Fully Automatic System to Accurately Segment the Proximal Femur in Anteroposterior Pelvic Radiographs

C. Lindner, S. Thiagarajah, J.M. Wilkinson, arcOGEN Consortium, G.A. Wallis and T.F. Cootes.
Proceedings of the UK Radiological Congress (UKRC) 2013, Liverpool, UK. Congress Handbook, page 56, 2013. (Abstract) [Talk]

Fully Automatic Proximal Femur Segmentation in Pelvic Radiographs using Random Forest Regression Voting

C. Lindner.
Invited talk at the Rank Prize Funds Symposium on
Medical Imaging Meets Computer Vision, Grasmere, UK. March, 2013. [Talk]

2012

Robust and Accurate Shape Model Fitting using Random Forest Regression Voting

T.F. Cootes, M. Ionita, C. Lindner and P. Sauer.
Proceedings of the 12th European Conference on Computer Vision (ECCV 2012, Part VII), Florence, Italy. Springer-Verlag Lecture Notes in Computer Science 7578, pages 278-291, 2012. (Full Paper) [Poster]

Accurate Fully Automatic Femur Segmentation in Pelvic Radiographs using Regression Voting

C. Lindner, S. Thiagarajah, J.M. Wilkinson, arcOGEN Consortium, G.A. Wallis and T.F. Cootes.
Proceedings of the 15th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2012, Part III), Nice, France. Springer-Verlag Lecture Notes in Computer Science 7512, pages 353-360, 2012. (Full Paper) [Poster] (MICCAI Travel Award)

2011

Einführung in Computational Social Choice:

Individuelle Strategien und kollektive Entscheidungen beim Spielen, Wählen und Teilen

J. Rothe, D. Baumeister, C. Lindner and I. Rothe.
Springer Spektrum, Heidelberg, xii+375 pp., 2011.

Short-term Variability of Proximal Femur Shape in Anteroposterior Pelvic Radiographs

C. Lindner, S. Thiagarajah, J.M. Wilkinson, arcOGEN Consortium, G.A. Wallis and T.F. Cootes.
Proceedings of the 15th Conference on Medical Image Understanding and Analysis (MIUA 2011), London, UK. BMVA Press, pages 69-73, 2011. (Full Paper) [Poster]

2010

A Market-Affected Sealed-Bid Auction Protocol

C. Lindner.
Proceedings of the 6th Hellenic Conference on Artificial Intelligence (SETN 2010), Athens, Greece. Springer-Verlag Lecture Notes in Artificial Intelligence 6040, pages 193-202, 2010. (Full Paper) [Talk] (Best Student Paper Award)

2009

Degrees of Guaranteed Envy-Freeness in Finite Bounded Cake-Cutting Protocols

C. Lindner and J. Rothe.
Proceedings of the 5th Workshop on Internet & Network Economics (WINE 2009), Rome, Italy. Springer-Verlag Lecture Notes in Computer Science 5929, pages 149-159, 2009. (Full Paper) [Talk]

Degrees of Guaranteed Envy-Freeness in Finite Bounded Cake-Cutting Protocols

C. Lindner and J. Rothe.
Technical Report arXiv:0902.0620v5 [cs.GT], ACM Computing Research Repository (CoRR), 37 pages, 2009.

Ultrasound Examinations of the Tongue while Playing Wind Instruments

W. Angerstein, A. Isselstein, C. Lindner, V. Aurich and T. Massing.

Proceedings of the International Congress on Music Physiology and Musicians’ Medicine, Freiburg, Germany. Musikphysiologie und Musikermedizin, vol. 16, no. 1, pages 7-8, 2009. (Extended Abstract) [Talk]

2008

Fixed-Parameter Tractability and Parameterized Complexity Applied to Problems From Computational Social Choice

C. Lindner and J. Rothe.
Supplement in the Mathematical Programming Glossary, A. Holder, editor. INFORMS Computing Society, 2008.

2007

An algorithm for Pseudo-3D-Representation of the Contour of the Tongue while Playing the Didgeridoo

C. Lindner, W. Angerstein, V. Aurich and T. Massing.
Proceedings of the International Symposium on Musical Acoustics (ISMA 2007), Barcelona, Spain. J. Agulló and A. Barjau, editors, ETSEIB, Department of Mechanical Engineering, Universitat Politècnica de Catalunya, pages 40-48, 2007. (Full Paper) [Talk]