Measurement of Cerebral Metabolic Rates of Glucose CMRglc
with [18F]FDG PET
A Practical Introduction with References.
24 May 2012
Wolfson Molecular Imaging Centre
University of Manchester
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Title
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Contents
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Background: the Irreversible Model for Deoxyglucose
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‘Gold Standard’ Measurement of CMRglc for Clinical Research
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The Use of a Standard Input Function
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Step 1: Invoke MICKI and Load Data
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Step 2: Plot Continuous Blood Curve
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Step 3: Plot Discrete Blood Samples
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Step 4: Create Whole Blood Input Function
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Step 5: Plasma-Over-Blood Ratio
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Step 6: Create Total Plasma Input Function
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The Estimation of the Combined Forward Rate Constant
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The Estimation of the Combined Forward Rate Constant
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Conversion of KI images into CMRglc images
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CMRglc measured on the HRRT in Manchester
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Acknowledgements
Full presentation