Dr.Thomas Andrew Waigh - Senior Lecturer

Contact: t.a.waigh@manchester.ac.uk
Last updated 20th June 2019

Dr. Thomas A. Waigh graduated from the University of Edinburgh in 1994 with a BSc in Physics. He earned his Ph.D. in biological physics in 1997 from the Cavendish Laboratory (University of Cambridge) with Dame Athene Donald. Subsequently he did a post-doc at the College de France, Paris (2 years) in the laboratory of Pierre Gilles de Gennes (Nobel Prize for Physics 1991). He was appointed to a lectureship in the Polymers and Complex Fluids Group in the Department of Physics of Leeds University in 2000 and moved to the Biological Physics group in the School of Physics and Astronomy of Manchester University in 2006 where he is currently a senior lecturer. He has published over 105 articles, has written 3 books and has two patents ('graphene oxide coated cover slips for fluorescence microscopy' and 'optical coherence tomography rheology'). His current H index is 32. He is PI for 5 Phd students, CI for 6 PhD students and 2 post-docs. He is treasurer of the Biological Physics group of the IOP.

Research Interests

A range of topics are covered in biological physics and soft matter. Currently his research is based on biological projects (endoplasmic reticulum, bacterial capsules, bacterial biofilms, antibodies and peptides), computational projects (single molecules, neural networks and machine learning) and photonics projects (super-resolution fluorescence microscopy, optical coherence tomography rheometry, microrheology and surface techniques).

a) Publications peer reviewed, * corresponding author.
95) M.W.Cao, S.Lu, N.N.Wang, H.Xu, H.Cox, R.H.Li, T.Waigh, Y.C.Han, Y.L.Wang, J.R.Lu, 'Enzyme-triggered morphological transition of peptide nanostructures for tumor-targeted drug delivery and enhanced cancer therapy', ACS Applied Materials and Interfaces, 2019, 11, 18, 16357-16366.
94) *S.Phanphak, P.Georgiades, R.Li, J.King, I.S.Roberts, T.A.Waigh, 'Super-resolution fluorescence microscopy study of the production of K1 capsules by E. coli: evidence for the differential distribution of the capsule at the poles and the equator of the cell', Langmuir, 2019, 35, 16, 5635-5646. The first super-resolution fluorescence microscopy study of capsule structure.
93) *H.Cox, M.Cao, H.Xu, T.A.Waigh, J.R.Lu, 'Active modulation of states of prestress in self-assembled short peptide gels', Biomacromolecules, 2019. 20, 4, 1719-1730. DOI: 10.1021/acs.biomac.9b00085. New machine learning algorithms were developed to explore single molecule dynamics.
92) *J.Hart, T.A.Waigh, J.R.Lu, I.S.Roberts, 'Microrheology and spatial heterogeneity of Staphylococcus aureus biofilms modulated by hydrodynamic shear and biofilm-degrading enzymes', Langmuir, 2019, 35, 3553-3561. Bacterial biofilms are demonstrated to harden under shear.
91) M.Wang, J.Wang, P.Zhou, J.Deng, Y.Zhao, Y.Sun, W.Yang, D.Wang, Z.Li, X.Hu, S.M.King, S.E.Rogers, H.Cox, T.A.Waigh, J.Yang, J.R.Lu, H.Xu, 'Nanoribbons self-assembled from short peptides demonstrate the formation of polar zippers between ?-sheets', Nature Communications, 2018, 9, 5118. DOI: 10.1038/s41467-018-07583-2. A new mechanism for ?-sheet formation is demonstrated.
90) *H.Cox, H.Xu, T.A.Waigh, J.R.Lu, 'Single-molecule study of peptide gel dynamics reveals states of prestress', Langmuir, 2018, 34, 14678-14689. DOI: 10.1021/acs.langmuir.8b03334. Machine learning with single molecule imaging demonstrates states of prestress in gels for the first time.
89) N.Korabel, T.A.Waigh, S.Fedotov, V.J.Allan, 'Non-Markovian intracellular transport with sub-diffusion and run-length dependent detachment rate', PLOS One, 2018, 0207436. DOI: 10.1371/journal.pone.0207436. Novel simulations of intracellular motor proteins that agree with experiments.
88) *R.Li, P.Georgiades, H.Cox, S.Phanphak, I.S.Roberts, T.A.Waigh, J.R.Lu, 'Quenched stochastic optical reconstruction microscopy (qSTORM) with graphene oxide', Scientific Reports, 2018, 8 16928. DOI: 10.1038/s41598-018-35297-4. Image contrasts improve by a factor of 100 and resolution by a factor of 2 with graphene oxide coated slides (see the related patent).
87) S.Fedotov, N.Korabel, T.A.Waigh, D.Han, V.J.Allan, 'Memory effects and Levy walk dynamics in intracellular transport of cargoes', Physical Review E, 2018, 98, 042136. DOI: 10.1103/PhysRevE.98.042136. Intracellular motors are shown to have memory effects for the first time.
86) R.Li, Z.Li, E.Pambou, P.Gutfreund, T.A.Waigh, J.R.P.Webster, J.R.Lu, 'Determination of PMMA residues on a chemical-vapor-deposited monolayer of graphene by neutron reflection and atomic force microscopy', Langmuir, 2018, 34, 5, 1827-1833. DOI: 10.1021/acs.langmuir.7b03117. This is the first neutron reflectivity study of graphene.
85) *P.Georgiades, V.J.Allan, G.D.Wright, P.G.Woodman, P.Udommai, M.A.Chung, T.A.Waigh, 'The flexibility and dynamics of the tubules in the endoplasmic reticulum', Scientific Reports, 2017, 7, 16474. The article investigates the mechanics of the endoplasmic reticulum (the main protein factory) for the first time in live cells. It presents an important fundamental topic in cellular biology e.g. for cancer research. DOI: 10.1038/s41598-017-16570-4.
84) *T.A.Waigh, 'Some critical questions in biological physics: a guided tour around the bugbears', Popular book, Institute of Physics, Nov 2017, 204 pages. A unique introduction to biological physics via some of the field's most important outstanding questions. ISBN: 978-0-7503-1375-9. Total sales 8,617 from 37 countries and 198 institutions. Very favourably reviewed by Prof. Pietro Cicuta (University of Cambridge, Physics) in Physics Today, December, 2018. physicstoday.scitation.org/doi/10.1063/PT.3.4094

83) *H.Cox, P.Georgiades, H.Xu, T.A.Waigh, J.R.Lu, 'Self-assembly of mesoscopic peptide surfactant fibrils investigated by STORM super-resolution microscopy', Biomacromolecules, 2017, 18, 11, 3481. This article investigates the structure and self-assembly of peptide surfactants for the first time with super-resolution fluorescence microscopy. Front cover of the journal. DOI: 10.1021/acs.biomac.7b00465
82) *A.V.Malm, T.A.Waigh, 'Elastic turbulence in entangled semi-dilute DNA solutions measured with optical coherence tomography', Scientific Reports, 2017, 7, 1186. A first account is provided of elastic turbulence in concentrated DNA solutions. DOI:10.1038/s41598-017-01303-4. The work received continued funding from a large £6M Unilever/EPSRC manufacturing grant (the technique also functions well with shampoo, which can also demonstrate elastic turbulence).
81) *T.A.Waigh, 'Advances in the microrheology of complex fluids', Reports on Progress in Physics, 2016, 79, 3, 74601-74663. This long review article is an update of my 2005 review article on microrheology. DOI:10.1088/0034-4885/79/7/074601
80) C.Chen, Y.Zhang, R.Fei, C.Cao, M.Wang, J.Wang, J.Bai, H.Cox, T.Waigh, J.R.Lu, H.Xu, 'Hydrogelation of the short self-assembling peptide I3QGK regulated by transglutaminase and use for rapid hemostasis', ACS Applied Materials and Interfaces, 2016, 8, 17833-17841. This is one of a series of articles on peptide synthetic biology; specifically for blood clotting. DOI:10.1021/acsami.6b04939
79) J.Bai, C.Chen, J.Wang, Y.Zhang, H.Cox, J.Zhang, Y.Wang, J.Penny, T.Waigh, J.R.Lu, H.Xu 'Enzymatic regulation of self-assembling peptide nanostructures and hydrogelation with highly selective antibacterial activities', ACS Applied Materials and Interfaces, 2016, 8, 15093-15102. This is another of a series of articles on peptide synthetic biology; specifically for broadband antibiotics. DOI: 10.1021/acsami.6b03770
78) *P.Georgiadis, V.J.Allan, M.Dickinson, T.A.Waigh, 'Reduction of coherent artefacts in super-resolution fluorescence localisation microscopy', Journal of Microscopy, 2016, 0, 1-9. This represents our first article on super-resolution fluorescence microscopy after 6 years work. DOI:10.1111/jmi.12453
77) N.Flores-Rodriguez, D.A.Kenwright, P.H.Chung, A.W.Harrison, F.Stefani, T.A.Waigh, V.J.Allan, P.G.Woodman, 'ESCRT-0 marks an APPL1-independent transit route for EGFR', Journal of Cell Science, 2015, 128, 755. This is one of a series of articles on intracellular endosomes. DOI: 10.1242/jcs.161786
76) *A.Malm, T.A.Waigh, S.Jaradat, R.Tomlin, 'Optical coherence tomography velocimetry with complex fluids', Journal of Physics: Conference Series, 2015, 602, 12039. DOI: 10.1088/1742-6596/602/1/012039. Demonstrates OCT rheology with starch suspensions.
75) *T.A.Waigh, 'Physics of living processes: a mesoscopic approach', textbook, 599 pages, Wiley, 2014. ISBN: 9781118449943. Total sales: 406 copies (April 2018).

74) B.Cowsill, X.Zhao, T.A.Waigh, S.Eapen, R.Davies, V.laux, M.Haertlein, V.T.Forsyth, J.R.Lu, 'Interfacial structure of immobilized antibodies and perdeuterated HSA in model pregnancy tests measured with neutron reflectivity', Langmuir, 2014, 30, 20, 5880-5887. DOI: 10.1021/la4036166
73) D.J.Batey, T.B.Edo, C.Rau, U.Wagner, Z.D.Pesic, T.A.Waigh, J.M.Rodenburg, 'Reciprocal space up sampling from real space over sampling in x-ray ptychography', Physical Review A, 2014, 89, 4, 43812. DOI: 10.1103/PhysRevA.89.043812
72) *P.Georgiadis, E. di Cola, R.K.Heenan, P.D.A.Pudney, D.J.Thornton, T.A.Waigh, 'A combined small-angle X-ray and neutron scattering study of the structure of purified soluble gastrointestinal mucins', Biopolymers, 2014, 101, 12, 1154. DOI: 10.1002/bip.22523
71) *P.Georgiadis, P.D.A.Pudney, S.Rogers, D.J.Thornton, T.A.Waigh, 'Tea derived galloylated polyphenols cross-link purified gastroinstestinal mucins', Plos One, 2014, 9, 8, 105302. DOI: 10.1371/journal.pone.0105302
70) H.Davies, P.D.Pudney, P.Georgiadis, T.A.Waigh, N.W.Hodson, C.E.Ridley, E.W.Blanch, D.J.Thornton, 'Reorganisation of the salivary mucin network by dietary components: insights from green tea polyphenols', Plos One, 2014, 9, 9, e108372. DOI: 10.1371/journal.pone.0108372
69) *A.V.Malm, A.W.Harrison, T.A.Waigh, 'Optical coherence tomography velocimetry of colloidal suspensions', Soft Matter, 2014, 10, 41, 8210-8215. DOI: 10.1039/C4SM01111B
68) A.Horsley, K.Rousseau, C.Ridley, W.Flight, A.Jones, T.A.Waigh, D.J.Thornton, 'Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis', Journal of Cystic Fibrosis, 2014, 13, 3, 260-266. DOI: 10.1016/j.jcf.2013.11.002
67) T.B.Edo, D.J.Batey, A.M.Maiden, C.Rau, U.Wagner, Z.D.Pesic, T.A.Waigh, J.M.Rodenburg, 'Sampling in X-ray ptychography', Physical Review A, 2013, 87, 53850. We were the first user group on the coherence imaging beam line of the Diamond synchrotron. DOI: 10.1103/PhysRevA.87.053850
66) *P.Georgiadis, P.D.A.Pudney, D.J.Thornton, T.A.Waigh, 'Particle tracking microrheology of purified gastointestinal mucins', Biopolymers, 2013, 101, 4, 366. Unilever funded project on tea. DOI: 10.1002/bip.22372
65) *A.W.Harrison, D.A.Kenwright, T.A.Waigh, P.G.Woodman, V.J.Allan, 'Modes of correlated angular motion in live cells across three distinct time scales', Physical Biology, 2013, 10, 3, 36002. DOI: 10.1088/1478-3975/10/3/036002
64) P.D.Coffey, M.J.Swann, T.A.Waigh, Q.S.Mu, J.R.Lu, 'The structure and mass of heterogeneous thin films measured with dual polarization interferometry and ellipsometry', RSC Advances, 2013, 3, 10, 3316-3324. DOI: 10.1039/c2ra22911k
63) *D.A.Kenwright, A.W.Harrison, T.A.Waigh, P.G.Woodman, V.J.Allan, 'First-passage-probability analysis of active transport in live cells', Physical Review E, 2012, 86, 31910. The first in vivo experimental measurements of a first passage distribution are demonstrated (a key statistical quantity for chemical reactions). DOI: 10.1088/1478-3975/10/3/036002
62) *T.A.Waigh, C.Rau, 'X-ray and neutron imaging with colloids', Current opinion in colloid and interface science, 2012, 17, 13-22. This review article considers the applications of new coherent X-ray techniques in soft matter systems. DOI: 10.1016/j.cocis.2011.07.001
61) B.J.Cowsill, T.A.Waigh, S.Eapen, R.Davies, J.R.Lu, 'Interfacial structure and history dependent activity of immobilised antibodies in model pregnancy tests', Soft Matter, 2012, 8, 9847-9854. DOI: 10.1039/C2SM26133B
60) *S.Jaradat, M.Harvey, T.A.Waigh, 'Shear-banding in polyacrylamide solutions revealed via optical coherence tomography velocimetry', Soft Matter, 2012, 8, 11677. DOI: 10.1039/C2SM26395E
59) A.Horsley, W.G.Flight, A.M.Jones, T.Waigh, D.J.Thornton, 'Are mucins important determinants of the physical properties of CF sputum?', Paediatric Pulmonology, 2012, 47, 35, 265-266. DOI: 10.1016/j.jcf.2013.11.002
58) *M.Harvey, T.A.Waigh, 'Optical coherence tomography velocimetry in controlled shear flow', Physical Review E, 2011, 83, 31502. A UK patent was awarded based on the results. DOI: 10.1103/PhysRevE.83.031502.
57) N.Flores-Rodriguez, S.S.Rogers, D.A.Kenwright, T.A.Waigh, P.G.Woodman, V.J.Allan, 'Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis', Plos One, 2011, 6, 9, e24479. DOI: 10.1371/journal.pone.0024479
56) B.J.Cowsill, P.D.Coffey, M.Yaseen, T.A.Waigh, N.J.Freeman, J.R.Lu, 'Measurement of the thickness of ultra-thin adsorbed globular protein layers with dual-polarisation interferometry: a comparison with neutron reflectivity', Soft Matter, 2011, 7, 7223. DOI: 10.1039/C1SM05500C
55) R.C.Sharma, T.A.Waigh, A.L.Mainia, S.N.Thakur, J.P.Singh, K.C.Lin, 'Vibrationally selective radiative and non-radiative transitions in gaseous hydrogen molecules', Spectrochimica Acta Part A, 2011, 79, 396-399. DOI: 10.1016/j.saa.2011.02.015
54) *T.A.Waigh, A.Papagiannopoulos, 'Biological and biomimetic comb polyelectrolytes', Polymers, 2010, 2, 57-70. DOI: 10.3390/polym2020057
53) *S.S.Rogers, N.Flores-Rodriguez, V.J. Allan, P.G.Woodman, T.A.Waigh, 'The first passage probability of intracellular particle trafficking', Physical Chemistry - Chemical Physics, 2010, 12, 3753-3761. DOI: 10.1039/b921874b
52) *M.Tassieri, T.A.Waigh, J.Trinick, A.Aggeli, R.M.E.Evans, 'Analysis of the linear viscoelasticity of polyelectrolytes by magnetic microrheometry - pulsed creep experiments and the one particle response', Journal of Rheology, 2010, 54, 1, 117-131. DOI: 10.1122/1.3266946
51) F.Pan, X.Zhao, S.Perumal, T.A.Waigh, J.R.Lu, J.R.P.Webster, 'Interfacial dynamic adsorption and structure of molecular layers of peptide surfactants', Langmuir, 2010, 26, 8, 5690-5696. DOI: 10.1021/la9037952
50) R.M.L.Evans, M.Tassieri, D.Auhl, T.A.Waigh, 'Direct conversion of rheological compliance measurements into storage and loss moduli', Physical Review E, 2009, 80, 1, 12501. DOI: 10.1103/PhysRevE.80.012501
49) P.D.Coffey, M.J.Swann, T.A.Waigh, F.Schedin, J.R.Lu, 'Multiple path length dual-polarization interferometry', Optics Express, 2009, 17, 13, 10959-10969. DOI: 10.1364/OE.17.010959
48) *S.Pregent, S.Adams, M.Butler, T.A.Waigh, 'The impact and deformation of a viscoelastic drop at the air-liquid interface', Journal of Colloid and Interface Science 2009, 331, 163-173. DOI: 10.1016/j.jcis.2008.11.012
47) H.Xu, J.Wang, S.Han, J.Wang, D.Yu, H.Zhang, D.Xia, X.Zhao, T.A.Waigh, J.R.Lu, 'Hydrophobic region induced transitions in self-assembled peptide nanostructures', Langmuir, 2009, 25, 7, 4115-4123. DOI: 10.1021/la802499n
46) *A.Papagiannopoulos, C.Fernyhough, T.A.Waigh, A.Radulescu, 'Scattering study of the structure of polystyrene sulfonate comb polyelectrolytes in solution', Macromolecular Chemistry and Physics 2008, 209, 2475-2486. Front cover of the journal. DOI: 10.1002/macp.200800428
45) *E.Di cola, G.Yakubov, T.A.Waigh, 'Double-globular structure of porcine stomach mucin: a small-angle scattering study', Biomacromolecules 2008, 9, 11, 3216. DOI: 10.1021/bm800799u
44) F.Pan, X.B.Zhao, T.A.Waigh, J.R. Lu, 'Interfacial adsorption and denaturisation of human milk and recombinant rice lactoferrin', Biointerfaces 2008, 3, 2, FB36-43. DOI: 10.1116/1.2965135
43) *S.S.Rogers, C.van de Walle, T.A.Waigh, 'Microrheology of bacterial biofilms in vitro: staphylococcus aureus and pseudomonas aeruginosa', Langmuir, 2008, 24, 13549-13555. DOI: 10.1021/la802442d
42) *M.Jahnel, T.A.Waigh, J.R.Lu, 'Thermal fluctuations of fibrin fibres at short time scales', Soft Matter 2008, 4, 1438 - 1442. DOI: 10.1039/B802555J
41) X.Zhao, Z.Q.Zhang, F.Pan, T.A.Waigh, J.R.Lu, 'Plasmid DNA complexation with phosphorylcholine diblock copolymers and its effects on cell transfection', Langmuir 2008, 24, 6881-6888. DOI: 10.1021/la800593q
40) R.C.Sharma, T.A.Waigh, J.P.Singh, 'Narrow band optical filter in fluorescein doped boric acid glass saturable absorber thin films', Optics Communications 2008, 281, 10, 2985-2988. DOI: 10.1016/j.optcom.2008.01.062
39) *A.Papagiannopoulos, T.A.Waigh, T.E.Hardingham, 'The viscoelasticity of self-assembled proteoglycan combs', Faraday Discussion 2008, 139, 337. DOI: 10.1039/B714864J
38) *S.S.Rogers, T.A.Waigh, J.Lu, 'Intracellular microrheology of motile amoeba proteus', Biophysical Journal 2008, 94, 2170-2178. Front cover of the journal. DOI: 10.1529/biophysj.107.123851
37) *M.Tassieri, R.M.L.Evans, L.Barbu-Tudoran, J.Trinick, T. A.Waigh, 'The self-assembly, elasticity and dynamics of cardiac thin filaments', Biophysical Journal, 2008, 94, 2170-2178. DOI: 10.1529/biophysj.107.116087
36) *M.Tassieri, R.M.L. Evans, L.Barbu Tudoran, G. Nasir Khaname, J. Trinick, T.A. Waigh, 'Dynamics of semi-flexible polymer solutions in the highly entangled regime', Physical Review Letters, 2008, 101, 198301. DOI: 10.1103/PhysRevLett.101.198301
35) *R.C. Sharma, A.Papagiannopoulos, T.A.Waigh, 'Optical coherence tomography picorheology of biopolymer solutions', Applied Physics Letters, 2008, 92, 173903. DOI: 10.1063/1.2917578
34) R.C.Sharma, T.A.Waigh, J.P.Singh, 'Modulated optical phase conjugation in rhodamine 110 doped boric acid films', Applied Physics Letters, 2008, 92, 101125. DOI: 10.1063/1.2897307
33) *E.de Luca, T.A.Waigh, M.Monkenbusch, J.S.Kim, H.S.Jeon, 'Neutron spin echo study of the dynamics of micellar solutions of randomly sulphonated polystyrene', Polymer, 2007, 48. DOI: 3930-3934. 10.1016/j.polymer.2007.05.027
32) X.Zhao, F.Pan, Z.Zhang, C.Grant, Y.Ma, S.P.Armes, Y.Tang, A.L.Lewis, T.Waigh, J.R.Lu, 'Nanostructure of polyplexes formed between cationic diblock copolymer and antisense oligodeoxynucleotide and its influence on cell transfection efficiency', Biomacromolecules 2007, 8, 3493-3502. DOI: 10.1021/bm7006482
31) G.E.Yakubov, A.Papagiannopoulos, E.Rat, T.A.Waigh 'The charge and interfacial behaviour of short side-chain heavily glycosylated porcine stomach mucin' Biomacromolecules 2007, 8, 3791-3799. DOI: 10.1021/bm700721c
30) G.E.Yakubov, A.Papagiannopoulos, E.Rat, R.L.Easton, T.A.Waigh, 'The molecular structure, and rheological properties of short side-chain heavily glycosylated porcine stomach mucin', Biomacromolecules 2007, 8, 3467-3477. DOI: 10.1021/bm700607w
29) S.S.Rogers, T.A.Waigh, X.Zhang, J.Lu, 'Precise particle tracking against a complicated background: polynomial fitting with a Gaussian weight', Physical Biology 2007, 4, 220-227. DOI: 10.1088/1478-3975/4/3/008
28) L.M.Carrick, A.Aggeli, N.Boden, J.Fisher, E.Ingham, T.A.Waigh, 'Effect of ionic strength on the self-assembly, morphology and gelation of pH responsive -sheet tape forming peptides', Tetrahedron 2007, 63, 31, 7457-7467. DOI: 10.1016/j.tet.2007.05.036
27) *A.J.Hodrien, T.A.Waigh, A.M.Voice, G.E.Blair, S.M.Clarke, 'Adsorption of DNA onto positively charged amidine colloidal spheres and the resultant bridging interaction', International Journal of Biological Macromolecules 2007, 41, 146-153. DOI: 10.1016/j.ijbiomac.2007.01.009
26) *Di Cola E, Waigh TA, Colby RH, 'Dynamic light scattering and rheology studies of aqueous solutions of amphiphilic sodium maleate containing copolymers', Journal of Polymer Science Pt. B- Polymer Physics 2007, 45, 7, 774-785. DOI: 10.1002/polb.21079
25) *T.A.Waigh, 'Applied biophysics: a molecular approach for physical scientists', undergraduate textbook, 2007, Wiley. 436 pages. ISBN-10: 047001718X. Total sales: 1,713 books. Translated into Russian 2008.

24) *A.Papagiannopoulos, T.A.Waigh, T.Hardingham, M.Heinrich, 'The solution structure and dynamics of cartilage aggrecan', Biomacromolecules 2006, 7, 2162-2172. DOI: 10.1021/bm060287d
23) C.J.Bell, L.M.Carrick, J.Katta, Z.Jin, E.Ingham, A.Aggeli, N.Boden, T.A.Waigh, J.Fisher, 'Self-assembling peptides as injectable lubricants for osteoarthritis', Journal of Biomedical Materials Research Pt A, 2006, 236-246. DOI: 10.1002/jbm.a.30672
22) *E. di Cola, T.A.Waigh, J.Trinick, L.Tschovrebova, W.Hintzen, 'The persistence length of titin from rabbit sacromere', Biophysical Journal, 88, 2005, 4095-4106. DOI: 10.1529/biophysj.104.054908
21) *L.Carrick, M.Tassieri, T.A.Waigh, A.Aggeli, N.Boden, C.Bell, J.Fisher, E.Ingham, R.M.L.Evans, 'The internal dynamic modes of charged self-assembled peptide fibrils', Langmuir, 21, 2005, 3733-3737. DOI: 10.1021/la046802f
20) *T.A.Waigh, 'Microrheology of complex fluids', Reports of Progress in Physics, 68, 2005, 685-742. DOI: 10.1088/0034-4885/68/3/R04
19) *E. de Luca, T.A.Waigh, J.S.Kim, W.Hintzen, 'Phase separation in randomly charged polystyrene sulphonate ionomers', Polymer, 46, 2005, 7109-7117. DOI: 10.1016/j.polymer.2005.05.096
18) *A.Papagiannopoulos, T.A.Waigh, A.Fluerasu, C.Fernyhough, A.Madsen 'Microrheology of polymeric solutions using X-ray photon correlation spectroscopy', Journal of Physics: Condensed Matter, 17, 2005, L279-285. DOI: 10.1088/0953-8984/17/25/L06
17) *A.Papagiannopoulos, C.M.Fernyhough, T.A.Waigh, 'The microrheology of polystyrene sulphonate combs in aqueous solutions', Journal of Chemical Physics 2005, 123, 214902. DOI: 10.1063/1.2136888
16) V.Castellato, I.Hamley, T.A.Waigh, 'Dynamic light scattering study of the dynamics of a gelled polymeric micellar system', Journal of Chemical Physics, 121, 22, 2004, 11474-11480. DOI: 10.1063/1.1818067
15) *E.Di Cola, N.Plucktaveesak, T.A.Waigh, R.H.Colby, J.S.Tan, W.Pyckhout-Hintzen, R.K.Heenan, 'Structure and dynamics in aqueous solutions of amphiliphilic maleic anhydride-containing alternating copolymers', Macromolecules 2004, 37, 8457-8465. DOI: 10.1021/ma049260h
14) J.Fundin, V.Castellato, Z.Yang, I.W.Hamley, T.A.Waigh, C.Price, 'A light scattering and X-ray scattering study of aqueous micellar solutions of a diblock copolymer of propylene oxide and ethylene oxide with solubilized alkylcyanobiphenyl liquid crystals', Journal of Macromolecular Science - Physics, 2004, B43, 5, 893-912. DOI: 10.1081/MB-200033253
13) C.J.Bell, L.M.Carrick, E.Ingham, A.Aggeli, N.Boden, T.A.Waigh, J.Fisher, 'Self-assembling peptide nanomaterials as injectable lubricants for osteoarthritis', Proceedings of the 5th symposium of the international cartilage repair society, 2004, 27-30. DOI: 10.1002/jbm.a.30672
12) P.J.Mawer, T.A.Waigh, R.Harding, T.C.B.McLeish, S.M.King, M.Bell, N.Boden, 'Small-angle neutron scattering from peptide nematic fluids and hydrogels under shear', Langmuir, 2003, 19, 12, 4940-4949. DOI: 10.1021/la0267342
11) *T.A.Waigh, A.Papagiannopoulos, A.Voice, R.Bansil, A.P.Unwin, C.D.Dewhurst, B.Turner, N.Afdhal, 'Entanglement coupling in porcine stomach mucin', Langmuir, 2002, 18, 7188-7195. DOI: 10.1021/la025515d
10) T.A.Waigh, R.Ober, C.E.Williams, J.C.Galin, 'Semi-dilute solutions of a solvophobic polyelectrolyte in nonaqueous solvents', Macromolecules, 2001, 34, 1973-1980. DOI: 10.1021/ma001086j
9) A.M.Donald, L.Kato, P.Perry, T.A.Waigh, 'Scattering studies of the internal structure of starch', Starch, 2001, 53, 504-512.
8) T.A.Waigh, M.J.Gidley,B.U.Komanshek, A.M.Donald, 'The phase transformations in starch during gelatinisation: a liquid crystalline approach', Carbohydrate Research, 2000, 328, 2, 165-176 (Model for gelatinisation confirmed: Macromolecules 2002, 35, 8852-8859). DOI: 10.1016/S0008-6215(00)00098-7
7) T.A.Waigh, K. Lisa Kato, Athene M. Donald, Michael J. Gidley, Chris J. Clarke, Christian Riekel 'Side-chain liquid-crystalline model for starch', Starch, 2000, 52, 12, 450-460. DOI: 10.1002/1521-379X(200012)52:12
6) T.L.Barsby, A.M.Donald, P.A.Perry, T.A.Waigh, 'Impact of internal granule structure on processing and properties', Starch: advances in structure and function', Royal Society of Chemistry, 2001, 271, 45-52. ISBN: 978-0-85404-860-1
5) T.A.Waigh, A.M.Donald, M.J.Gidley, F.Heidelbach, C.Riekel, 'Analysis of the native structure of starch granules with microfocus small-angle X-ray scattering', Biopolymers, 1999, 49, 91-105. DOI: 10.1002/(SICI)1097-0282(199901)49:1
4) T.A.Waigh, P.Perry, A.M.Donald, M.J.Gidley, C.Riekel, 'Chiral side-chain liquid-crystalline properties of starch', Macromolecules, 1998, 31, 22, 7980-7984. DOI: 10.1021/ma971859c
3) C.He, A.M.Donald, A.C.Griffin, T.Waigh, A.H.Windle, 'Self-assembly of hydrogen bonded main chain liquid crystal copolymer: structure and thermal stability', Journal of Polymer Physics B, 1998, 36, 1617-1624. DOI: 10.1002/(SICI)1099-0488(19980730)36:10
2) T.A.Waigh, M.F.Butler, I.Hopkinson, F.Heidelbach, C.Riekel, A.M.Donald, 'Analysis of the native structure of starch granules with X-ray microfocus diffraction', Macromolecules, 1997, 30, 13, 3813-3820. Reviewed in Nature, P.Calvert, 1997. DOI: 10.1021/ma970075w
1) T.A.Waigh, P.J.Jenkins, A.M.Donald, 'Quantification of water in carbohydrate lamellae using SANS', Faraday Discussion, 1996, 103, 325-337. DOI: 10.1039/FD9960300325

PhD students

Current (PI)

Hannah Perkins,

Johanna Blee,

Sorasak Phanphak,

Lin Zhang,

Jack Hart,

Current (CI)

Sean Ruane,

Mingrui Liao,

Cynthia Li,

Haoning Gong,

Daniel Han,

Liliana Correia,

Completed PhD students: Henry Cox, Pantelis Georgiadis, Ben Cowsill, Ruiheng Li, Stive Pregent, Alex Malm, James Sanders, Emanuela di Cola, Manlio Tassieri, Alison Hodrien, Robert Harrand, Aris Papagiannopoulos
Completed Masters students: Andrew Chung, Marcus Jahnel, Ross Tomlin, James Sanders, David Pearce, Johanna Chu