Dr. Sizheng Steven Zhao

Publications

Research Metrics:
Citations: ~7700
h-index: 44
i10-index: 114

• Lyu H, Zhao SS, Zhang L, Wei J, Li X, Li H, Liu Y, Yin P, Norvang V, Yoshida K, Tedeschi S, Zeng C, Lei G, Tang P, Solomon DH. Denosumab and Incidence of Type 2 Diabetes Among Patients with Osteoporosis: A population-based cohort study. BMJ 2023. Link
• Zhao SS, Gill D. Genetically proxied IL-6 receptor inhibition and risk of polymyalgia rheumatica. Annals of the Rheumatic Diseases 2022. Link
• Zhao S, Karhunen V, Morris AP, Gill D. ADAMTS5 as a therapeutic target for osteoarthritis: Mendelian randomisation study. Annals of the Rheumatic Diseases 2022. Link
• Zhao S, Macfarlane GJ, Jones GT, Gaffney K, Hughes DM, Moots RJ, Goodson NJ. Smoking does not protect axial spondyloarthritis patients from attacks of uveitis. Annals of the Rheumatic Diseases 2019. Link
• Zhao SS, Barton A, Bowes J. Genetically proxied TYK2 inhibition is associated with reduced sarcoidosis susceptibility. Ann Rheum Dis 2022. Link
• Zhao SS, Hyrich K, Yiu Z, Barton A, Bowes J. Genetically proxied IL-13 inhibition is associated with risk of psoriatic disease. Arthritis & Rheum 2024. Link
• Zhao S, Lyu H, Solomon DH, Yoshida K. Improving rheumatoid arthritis comparative effectiveness research through causal inference principles: systematic review using a target trial emulation framework. Annals Rheum Dis 2020. Link
• Yuan S, Chen J, Geng J, Zhao SS, Yarmolinsky J, Arkema EV, Abramowitz S, Levin MG, Tsilidis KK, Burgess S, Damrauer SM, Larsson SC. Genome-wide association analysis reveals genetic loci, lifestyle factors, inflammatory markers, and circulating proteins as risk factors for sarcoidosis. Nature Communications 2025. Link
• Zhao SS, Yiu Z. Genetically proxied interleukin-6 receptor inhibition increases risk of atopic dermatitis. J Allergy Clin Immunol 2024. Link
• Zhao SS, Yiu Z, Barton A, Bowes J. Lipid-lowering drugs and risk of psoriasis: a mendelian randomization study. JAMA Derm 2022. Link
• Lyu H, Yoshida K, Zhao S, Wei J, Zeng C, Tedeschi SK, Leder BZ, Lei G, Tang P, Solomon DH. Delayed Denosumab Injections and Fracture Risk Among Subjects with Osteoporosis: A population-based cohort study. Annals of Internal Medicine 2020. Link
• Zhao SS, Hernandez G, Alam U. Risk of psoriatic arthritis among patients receiving apremilast versus methotrexate for psoriasis. Journal of the American Academy of Dermatology 2025. Link
• Yarmolinsky J, Robinson JW, Mariosa D, Karhunen V, Huang J, Dimou N, Zhao SS, et al. Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis. EBioMedicine 2024. Link
• Ramiro S, Nikiphorou E, Sepriano A, [...] Zhao SS, Ziade N, van der Heijde D. ASAS-EULAR recommendations for the management of axial Spondyloarthritis: 2022 update. Ann Rheum Dis 2022. Link
• Fragoulis GE, Nikiphorou E, Dey M, Zhao SS, Courvoisier DS, [...] Hyrich KL. 2022 EULAR Recommendations for screening and prophylaxis of chronic and opportunistic infections in adults with autoimmune inflammatory rheumatic diseases. Ann Rheum Dis 2022. Link
• Zhao SS, Harrison SR, Thompson B, [...] Gaffney K. Executive summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs. Rheumatology 2025. Link
• Zhao SS, Harrison SR, Thompson B, [...] Gaffney K. The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs. Rheumatology 2025. Link

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• Zhao SS, Harvey NR, Nam B, Li Z, Bradbury LA, Gensler LS, Wordsworth BP, Ward MM, Weisman MH, Learch TJ, Reveille JD, Kim TH, Brown MA. Impact of comorbidities and extra-musculoskeletal manifestations on radiographic progression in ankylosing spondylitis. Rheumatology 2026 Link
• Johnston S, Zuckerman B, Sharma A, Alam U, Zhao SS. Incidence of gout in spondyloarthritis. Rheum Adv Pract 2026. Link
• Williams JC, Kieu PL, Zuckerman BP, Alam U, Zhao SS. Enteropathic arthritis is associated with an increased risk of major adverse cardiovascular events and venous thromboembolism. Rheum Adv Pract 2025.Link
• Williams JC, Helliwell PS, McGonagle DG, Freeston JE, Ferguson LD, Gullick N, Harrison SR, Laws P, De Marco G, Packham J, Shams K, Tan AL, Tillett W, Weddell J, Zhao SS, Sattar N, Siebert S, Marzo-Ortega H. Beyond the scales: time to prioritise treatment of obesity in psoriatic disease. Ann Rheum Dis 2026. Link
• Younis A, Henney AE, Riley DR, Anson M, Zhao SS, Ibarburu GH, Malik RA, Su L, Lip GYH, Cuthbertson DJ, Alam U. Target trial emulations for tirzepatide, semaglutide and SGLT2-inhibitors for dementia in patients with type 2 diabetes: real world evidence from a retrospective cohort study. Diabetes, Research & Clinical Practice 2026. Link
• Zhao SS, Webers C, Nikiphorou E, van der Heijde D, Braun J, Kiltz U, Ramiro S, Boonen A. Disease activity and mental health symptoms in axial spondyloarthritis: concordant or discordant? Rheumatology 2025. Link
• Ling S, Bennett J, […] Zhao S, Holroyd C. Biologic and targeted synthetic DMARD safety in inflammatory arthritis: British Society for Rheumatology guideline scope. Rheum Adv Prac 2025. Link
• Jiang Y, Tan S, Zhao SS, Qin K, Xie Y, Cui X, Tang P, Lyu H, Zhang L. Impact of Prehospital Delay on Postoperative Complications and 5-Year Mortality in Older Adults with Hip Fractures. Injury 2025. Link
• Zhao SS, Woolf B, Rogne T, Gill D. Genetically proxied TNF inhibition and pregnancy-related maternal and fetal outcomes in the general population: a Mendelian randomization study. Rheum Adv Prac 2025. Link
• Fragoulis GE, Zhao SS. Therapeutic strategy in psoriatic arthritis: choosing the right treatment for the right patient. Therapeutic Advances in Musculoskeletal Disease 2025. Link
• Hughes M, Jude E, McMahan ZH, Alam U, Ruaro B, Zhao SS. An epidemiological study estimating the burden of cancer risk in patients with Raynaud’s phenomenon. Clin Rheum 2026. Link
• Williams JC, Rogers K, Southworth J, Hum RM, Ho P, Zhao SS. High prevalence and distinct patterns of metabolic syndrome in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis: A population-based study. Rheum Int 2025. Link
• Hughes M, Ruaro B, McMahan Z, Alam U, Jude E, Zhao SS. Raynaud’s phenomenon is associated with an increased risk of cardiovascular disease and venous thromboembolism. Semin Arthritis Rheum 2025. Link
• Williams JC, Rogers K, Southworth J, Hum RM, Ho P, Zhao SS. The comparative prevalence of comorbidities across rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis. Rheum Adv Pract 2025. Link
• Zhao SS, Hernandez G, Alam U. Risk of cardiovascular disease and cancer in patients initiating JAK versus IL-4/-13 inhibitors for atopic dermatitis. International Journal of Dermatology 2025. Link
• Zhao SS, Liu W, Johnston S, Alam U, Gao S. Calcium pyrophosphate deposition disease is associated with increased risk of fractures: a retrospective cohort study using electronic health record data. Osteoarthritis and Cartilage 2025. Link
• Essa H, Welters I, Yasin I, Henney A, Hernandez G, AlBadri S, Zhao S, Lip G, Cuthbertson D, Alam U. Increased cardiovascular risk in people with type 2 diabetes and periodontitis: An analysis from a global real world federated database. British Dental Journal 2025. Link
• Yao C, Zhang Y, Zhao SS, Ren J, Sun P, Kong L, Tao J, Li J, Fang M, Zhu Q. Effect of physical activity on chronic widespread pain: insights from meta-analysis and two-sample Mendelian randomization. Journal of Pain Research 2025. Link
• Williams JC, Rogers K, Coulson K, Hughes DM, Hughes M, Zhao SS. Association between beta-1-adrenoceptor blockade and risk of Raynaud’s phenomenon: Mendelian randomization study. Journal of Scleroderma and Related Disorders 2025. Link
• Ludwig RJ, Anson M, Zirpel H, Thaci D, Olbrich H, Bieber K, Kridin K, Dempfle A, Curman P, Zhao SS, Alam U. A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX. Frontiers in Pharmacology 2025. Link
• Zhao SS, Riley D, Hernandez G, Alam U. Comparative safety of JAK inhibitors versus TNF or IL-17 inhibitors for cardiovascular disease and cancer in psoriatic arthritis and axial spondyloarthritis. Clin Ther 2025. Link
• Marshall A, Elshafei M, Preston FG, Burgess J, Goodson N, Fallon N, Frank B, Zhao SS, Alam U. Small Fibre Pathology in Fibromyalgia. Pain and Therapy 2025. Link
• Riley DR, Henney A, Anson M, Hernadez G, Zhao SS, Alam U, Wilding JPH, Craig S, Cuthbertson DJ. The cumulative impact of type 2 diabetes and obstructive sleep apnoea on cardiovascular, liver, diabetes-related and cancer outcomes. Diabetes, Obesity & Metabolism 2024. Link
• Chandratre P, Sabido-Sauri R, Zhao SS, Abhishek A. Gout, hyperuricemia and Psoriatic Arthritis: an evolving conundrum. Current Rheumatology Reports 2025. Link
• Williams JC, Alam U, Zhao SS. Incidence of Uveitis and Inflammatory Bowel Disease in Psoriatic Disease, and Psoriatic Disease in Uveitis and Inflammatory Bowel Disease. Rheumatology 2025. Link
• Hughes DM, Yiu Z, Zhao SS. External validation of the accuracy of cardiovascular risk prediction tools in psoriatic disease: A UK Biobank Study. Clin Rheum 2025. Link
• Henney AE, Riley DR, Hydes TJ, Anson M, Ibarburu GH, Zhao SS, Cuthbertson DJ, Uazman A. Metabolic syndrome traits differentially and cumulatively influence micro- and macrovascular disease risk in patients with MASLD. Liver International 2024. Link
• Anson M, Henney AE, Broadwell N, Zhao SS, Ibarburu GH, Lip GYH, Wilding JPH, Cuthbertson DJ, Alam U. Incidence of new onset type 2 diabetes in adults living with obesity treated with tirzepatide or semaglutide: real world evidence from an international retrospective cohort study. eClinicalMedicine 2024. Link
• Essa H, Ding WY, Rana F, Zhao SS, Anson M, Austin P, Hernandez G, Lal P, Lip GYH, Alam U. Aspirin and ticagrelor's versus aspirin and clopidogrel or pasugrel and the effect on staphylococcal infection: A real-world study. Clinical Therapeutics 2024. Link
• Weddell J, Harrison SR, Bennet AN, Gaffney K, Jones GT, Machado PM, Packham J, Sengupta R, Zhao SS, Siebert S, Marzo-Ortega H. British Axial Spondyloarthritis Inception Cohort (BAxSIC): A protocol for a multicentre real world observational cohort study of early axial Spondyloarthritis. Rheum Adv Prac 2024. Link
• Riley DR, Hydes T, Hernadez G, Zhao SS, Alam U, Cuthbertson DJ. The synergistic impact of type 2 diabetes and MASLD on cardiovascular, liver, diabetes-related and cancer outcomes. Liver International 2024. Link
• Henney AE, Riley DR, O'Connor B, Hydes TJ, Anson M, Zhao SS, Alam U, Cuthbertson DJ. Denosumab for osteoporosis reduces incidence of type 2 diabetes, risk of foot ulceration and all-cause mortality in adults, compared to bisphosphonates: an analysis of real-world, cohort data, with a systematic review and meta-analysis. Diabetes, Obesity & Metabolism 2024. Link
• Zhao SS, Burgess S, Gill D. Glucagon-like peptide-1 receptor agonism and suicide risk: evidence from Mendelian randomization. Journal of the American Heart Association 2024. Link
• Zhao SS, Mackie SL, Larsson SC, Burgess S, Yuan S. Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation. Rheumatology 2024. Link
• Zhao SS, Gill D. Genetically proxied IL-6 receptor inhibition and coronary artery disease risk in a Japanese population. Clin Ther 2024. Link
• Lyon M, Zhao SS, Jani M, Chinoy H, Barton A, Bluett J. The Influence of Deprivation in the Outcomes of Psoriatic Arthritis within the UK - utilising OUTPASS data. Rheum Adv Prac 2024. Link
• Anson M, Malik A, Zhao SS, Austin P, Ibarburu GH, Jaffar S, Garrib A, Cuthbertson D, Alam U. Treating type 2 diabetes with early, intensive, multi-modal pharmacotherapy: real world evidence from an international collaborative database. Journal of Diabetes Research 2024. Link
• Zhao SS, Cuthbertson DJ, Alam U. Human genetic evidence supports Fibroblast Growth Factor 21 (FGF21) as a novel therapeutic target for gout. Rheumatology 2024. Link
• Dubovyk V, Vasileiadis GK, Fatima T, Zhang Y, Kapetanovic MC, Kastbom A, Rizk M, Söderbergh A, Zhao SS, van Vollenhoven RF, Hetland ML, Haavardsholm EA, Nordström D, Nurmohamed MT, Gudbjornsson B, Lampa J, Østergaard M, Heiberg MS, Sokka-Isler T, Gröndal G, Lend K, Hørslev-Petersen K, Uhlig T, Rudin A, Maglio C. Obesity is a risk factor for poor response to treatment in early rheumatoid arthritis - a NORD-STAR analysis. RMD Open 2024 Link
• Anson M, Zhao SS, Alam U. Effect of combination pioglitazone with SGLT2i or GLP-1 RA on outcomes in type 2 diabetes: A systematic review, meta-analysis, and real-world study from an international federated database. Diabetes, Obesity and Metabolism 2024. Link
• Zhao SS. IL-6 receptor inhibition is not associated with body weight or composition: Mendelian randomisation study. Clinical rheumatology 2024. Link
• Marshall A, Rapteas L, Burgess J, Riley D, Anson M, Matsumoto K, Bennett A, Kaye S, Marshall A, Dunham J, Fallon N, Zhao SS, Pritchard A, Goodson N, Malik RA, Goebel A, Frank B, Alam U. Small fibre pathology, small fibre symptoms and pain in fibromyalgia syndrome. Scientific Reports 2024. Link
• Eleftheriadou A, Riley D, Zhao SS, Austin P, Hernandez G, Lip GYH, Jackson TL, Wilding JPH, Alam U. Risk of Diabetic Retinopathy and Diabetic Macular Oedema with Sodium-Glucose Co-transporter 2 Inhibitors and Glucagon-like Peptide 1 Receptor Agonists in type 2 Diabetes: a real-world data study from a global Federated Database. Diabetologia 2024. Link
• Michelena X, Sepriano A, Zhao SS, López-Medina C, Collantes-Estévez E, Font-Ugalde P, Juanola X, Marzo-Ortega H. Exploring the unifying concept of Spondyloarthritis: a latent class analysis of the REGISPONSER registry. Rheumatology 2025. Link
• Lai JYM, Riley DR, Anson M, Henney A, Cuthbertson DJ, Hernandez G, Austin P, Lip GYH, Zhao SS, Kacjson TL, Nabrdalik K, Alam U. Cardiovascular outcomes with intravitreal anti-vascular endothelial growth factor therapy in patients with diabetes: a real-world data analysis. Diabetes Therapy 2024. Link
• Zhao SS, Baker MC, Galloway JB. IL-6 receptor inhibition and risk of sarcoidosis: a Mendelian randomization study. Rheumatology 2024. Link
• McDermott GC, Monshizadeh A, Selzer F, Zhao S, Ermann J, Katz JN; Factors associated with diagnostic delay in axial spondyloarthritis: impact of clinical factors and social vulnerability. Arthritis Care Res 2023. Link
• Zhao SS. Examining the causal link between TNF inhibition and alopecia areata using Mendelian randomization. Clin rheum 2023. Link
• Thompson W, Swain S, Zhao SS, Kamps A, Coupland C, Kuo C, Bierma-Zeinstra S, Runhaar J, Doherty M, Zhang W. Causal association between subtypes of osteoarthritis and common comorbidities: a Mendelian Randomisation study. Osteoarthritis and Cartilage Open 2023. Link
• Thompson W, Swain S, Zhao SS, Coupland C, Kuo C, Doherty M, Zhang W. Causal associations of central and peripheral risk factors with knee osteoarthritis: a longitudinal and Mendelian Randomisation study using UK Biobank data. Pain 2023. Link
• Kearsley-Fleet L, Rokad A, Tsoi MF, Zhao SS, Lunt M, Watson K, BSRBR-RA, Hyrich KL. Outcomes following switching from etanercept originator to etanercept biosimilar in 1024 RA patients: A matched-analysis of the BSRBR-RA. Rheumatology 2023. Link
• Zhao SS, Rajeswaran T, Mackie SL, Yarmolinsky J. Genetically proxied IL-1 receptor antagonism and risk of polymyalgia rheumatica. Rheumatology 2023. Link
• Zhao SS, Burgess S. Vitamin D is associated with reduced risk of Sjögrens syndrome: a Mendelian randomization study. Rheumatology 2023. Link
• Zhao SS, Mason A, Gjekmarkaj E, Yanaoka H, Burgess S. Associations between vitamin D and autoimmune diseases: Mendelian randomization analysis. Seminars in arthritis and rheumatism. Seminars in Arthritis and Rheumatism 2023. Link
• Anson M, Zhao SS, Austin P, Hernández Ibarburu G, Malik RA, Alam U. SGLT2i and GLP-1 RA therapy in Type 1 diabetes and reno-vascular outcomes: a real-world study. Diabetologia 2023. Link
• Anson M, Zhao SS, Esa H, Austin P, Hernández Ibarburu G, GYH Lip, Alam U. Metformin and SGLT2i as first line combination therapy in Type 2 diabetes: a real-world study with a focus on ethnicity. Clinical Therapeutics 2023. Link
• Zhao SS, Harrison SR, Chan A, Clarke N, Davis C, Eddison J, Gregory WJ, Jones GT, Marzo-Ortega H, Murphy DJ, Sandhu V, Sengupta R, Siebert S, Thompson B, Webb D, Yates M, Gaffney K. Treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs: the British Society for Rheumatology guideline scope. Rheumatol Adv Pract 2023. Link
• Zhao SS, Rogers K, Kearsley-Fleet L, Watson K, Bosworth A, Galloway J, Verstappen S, Plant D, Barton A, Hyrich KL, Humphreys JH. Socioeconomic deprivation is associated with reduced response and lower treatment persistence with anti-TNF therapies in people with rheumatoid arthritis. Rheumatology 2023. Link
• Michelena X, Zhao SS, Marco-Pascual C, et al. Diagnostic delay is associated with Uveitis and Inflammatory Bowel Disease in Ankylosing Spondylitis: a multi-centre cohort study of extra-musculoskeletal manifestations in Spondyloarthritis. Rheumatology 2023. Link
• Kearsley-Fleet L, Rokad A, Tsoi MF, Zhao SS, Lunt M, Watson K, BSRBR-RA, Hyrich KL. Etanercept originator versus etanercept biosimilar for the treatment of rheumatoid arthritis as a first biologic: results from the BSRBR-RA. Rheumatology 2023. Link
• Dobbie LJ, Pittam B, Zhao SS, Alam U, Barber TM, Cuthbertson DJ. Childhood, adolescent and adulthood adiposity are associated with risk of polycystic ovary syndrome (PCOS): a Mendelian Randomisation Study with Systematic Review and Meta-analysis. Human Reproduction 2023. Link
• Zhao SS, Holmes MV, Alam Uazman. Disentangling the relationships between depression and chronic widespread pain: a Mendelian randomisation study. Semin Arthritis Rheum 2023. Link
• Zhao SS, Dyball S. Cholesteryl ester transfer protein (CETP) inhibition is associated with reduced risk of Sjögrens disease. Rheumatology 2023. Link
• Vasileiadis GK, Sayols S, Zhao SS, Fatima T, Maglio C. Adipokines and risk of rheumatoid arthritis: a two-sample multivariable Mendelian randomisation study. PLoS ONE 2023. Link
• Kouranloo K, Ashley A, Zhao SS, Dey M. Pulmonary manifestations in VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome: a systematic review. Rheum Int 2023. Link
• Zhao S, Lyu H, Wei J, Zeng C, Lei G, Mackie SL. Angiotensin receptor blockade is associated with increased risk of giant cell arteritis. Rheumatology 2022. Link
• Zhao S, Bellou E, Verstappen SMM, Cook MJ, Sergeant JC, Warren RB, Barton A, Bowes J. Risk factors and comorbidities in psoriatic disease: observational analysis of the UK biobank and Mendelian randomization. Rheumatology 2022. Link
• Fragoulis GE, Dey M, Zhao SS, Schoones J, Courvoisier D, Galloway J, Hyrich K, Nikiphorou E. Systematic literature review informing the 2022 EULAR recommendations on the screening and prophylaxis of chronic and opportunistic infections. RMD Open. Link
• Dey M, Bechman K, Zhao S, Fragoulis GE, Smith C, Cope A, Nikiphorou E, Hyrich KL, Galloway J. Infection profile of immune-modulatory drugs used in autoimmune diseases: Analysis of summary of product characteristic data. RMD Open 2022. Link
• Dey M, Bechman K, Zhao S, Fragoulis GE, Smith C, Cope A, Nikiphorou E, Hyrich KL, Galloway J. Assessment and diagnosis of the acute hot joint: A systematic review and meta-analysis. Rheumatology 2022. Link
• Zhao S, Rajasundaram S, Karhunen V, Alam U, Gill D. Sodium-glucose cotransporter 1 inhibition and gout risk: Mendelian randomisation study. Seminars in Arthritis and Rheumatism 2022. Link
• Zhao SS, Bowes J, Barton A, Davey Smith G, Richardson, TG. Separating the effects of childhood and adult body size on inflammatory arthritis: Mendelian randomization study. RMD Open 2022. Link
• Zhao SS, Bovijn J, Hughes DM, Sha T, Zeng C, Lyu H. Genetically predicted vitamin K levels and risk of osteoarthritis: Mendelian randomization study. Seminars in Arthritis and Rheumatism 2022. Link
• Gialouri CG, Evangelatos G, Zhao SS, Kouna K, Karamanakos A, Iliopoulos A, Tektonidou MG, Sfikakis PP, Fragoulis GE. Depression and anxiety in a real-world psoriatic arthritis longitudinal study. Should we focus more on patients perception? Clinical and Experimental Rheumatology 2022. Link
• Zhao SS, Kearsley-Fleet L, Bosworth A, Watson K, BSRBR-RA, Hyrich KL. Effectiveness of sequential biologic and targeted disease modifying anti-rheumatic drugs for rheumatoid arthritis. Rheumatology 2022. Link
• Zhao SS, Holmes MV, Alam U. Chronic pain is associate with increased risk of developing and being hospitalised for COVID-19: Mendelian randomization study. Rheumatology 2022. Link
• Lyu H, Zhao SS, Li J, Li X, Wang Y, Xie D, Zeng C, Lei G, Wei J. Denosumab versus alendronate for risk of community-acquired pneumonia: A population-based cohort study. JCEM 2022. Link
• Qian Y, He Z, Zhao SS, Liu B, Chen Y, Sun X, Ye D, Jiang X, Zheng H, Wen C, Zheng H, Mao Y. Genetically Determined Circulating Levels of Cytokines and the Risk of Rheumatoid Arthritis. Frontiers in Genetics 2022. Link
• Rajasundaram S, Rahman R, Woolf B, Zhao S, Gill D. Morning Plasma Cortisol and Circulating Inflammatory Cytokine Levels: a Mendelian Randomisation Study. Genes 2022. Link
• Zhao S, Nikiphorou E, Boonen A, Mediana CL, Dougados M, Ramiro S. Association between individual and country-level socioeconomic factors and work participation in peripheral and axial spondyloarthritis. Seminars in Arthritis and Rheumatism 2021. Link
• Zhao S, Nikiphorou E, Young A, Kiely PDW. Large joint disease in rheumatoid arthritis and the role of rheumatoid factor. Results from the Early Rheumatoid Arthritis Study. Rheumatology International 2021. Link
• Zhao S, Holmes MV, Zheng J, Sanderson E, Carter AJ. The impact of education inequality on rheumatoid arthritis risk is mediated by smoking and body mass index: Mendelian randomization study. Rheumatology 2021. Link
• Capelusnik D, Zhao S, Boonen A, Ziade N, Lopez-Medina C, Dougados M, Nikiphorou E, Ramiro S. Individual and country-level socioeconomic factors and health outcomes in spondyloarthritis: analysis of the ASAS perSpA study. Rheumatology 2021. Link
• Zhao S, Maglio C, Hughes D, Cook J. Body fat composition and risk of rheumatoid arthritis: Mendelian randomization study. Arthritis & rheumatology 2021. Link
• Dey M, Zhao S, Moots RJ, Landewe RB, Goodson NJ. Assessing the effect of increased body mass index on response to conventional synthetic DMARD treatment in rheumatoid arthritis. Rheumatology 2021. Link
• Cox P, Gupta S, Zhao S, Hughes DM. The Incidence and prevalence of cardiovascular diseases in gout: a systematic review and meta-analysis. Rheum Int 2021. Link
• Zhao S, Qian Y, Mackie SL, Wen C, Mao Y. Genetically predicted serum urate levels have no causal role in anxiety or depression. Rheum Int 2021. Link
• Zhao S, Jones GT, Hughes DM, Moots RJ, Goodson NJ. Depression and anxiety symptoms at TNF inhibitor initiation are associated with impaired treatment response in axial spondyloarthritis. Rheumatology 2021. Link
• Michelena X, Zhao S, Dubash S, Dean LE, Jones GT, Marzo-Ortega H. Similar biologic drug response regardless of radiographic status in axial spondyloarthritis: data from the BSRBR-AS registry. Rheumatology 2021 Link
• Zhao S, Jones GT, Macfarlane GJ, Hughes DM, Moots RJ, Goodson NJ. Comorbidity and response to TNF inhibitors in axial spondyloarthritis: longitudinal analysis of the BSRBR-AS. Rheumatology 2020 Link
• DiIorio M, Sobiesczcyk P, Xu C, Huang W, Ford J, Zhao S, Solomon DH, Docken W, Tedeschi SK. Associations among temporal and large artery abnormalities on vascular ultrasound in giant cell arteritis. Scandinavian Journal of Rheumatology 2020. Link
• Zhao S, Pittam B, Harrison NL, Ahmed AE, Goodson NJ, Hughes DM. Diagnostic delay in axial spondyloarthritis: a systematic review and meta-analysis. Rheumatology 2020. Link
• Zhao S, Jones GT, Macfarlane GJ, Hughes DM, Moots RJ, Goodson NJ. Association between comorbidities and disease activity in axial spondyloarthritis: results from the BSRBR-AS. Rheumatology 2020. Link
• Zhao S, Robertson S, Reich T, Harrison NL, Moots RJ, Goodson NJ. Prevalence and impact of comorbidities in axial spondyloarthritis: systematic review and meta-analysis. Rheumatology 2020. Link
• Benson R, Zhao S, Goodson NJ, Abernethy R, Mewar D, Barnes T. Biologic monotherapy in the biologic naïve patient with rheumatoid arthritis: Results from an observational study. Rheumatology International 2020. Link
• Lyu H, Zhao S, Yoshida K, Tedeschi SK, Xu C, Nigwekar SU, Leder BZ, Solomon DH. Delayed Denosumab Injections and Bone Mineral Density Response: An Electronic Health Record-based Study. J Clin Endocrinol Metab 2020. Link
• Zhao S, Hong C, Cai T, Chang X, Huang J, Ermann J, Goodson NJ, Solomon DH, Cai T, Liao KP. Incorporating natural language processing to improve classification of axial spondyloarthritis using electronic health records. Rheumatology 2019. Link
• Dey M, Zhao S, Goodson N. Global public interest in infectious and non-infectious arthritis: an evaluation using Google Trends. Rheumatology 2019. Link
• Zhao S, Miller N, Harrison N, Duffield SJ, Dey M, Goodson N. Systematic review of mental health comorbidities in psoriatic arthritis. Clinical Rheumatology 2019. Link
• Zhao S, Yoshida K, Jones GT, Hughes DM, Duffield SJ, Tedeschi SK, Lyu H, Moots RJ, Solomon DH, Goodson NJ. Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis. Arthritis Research & Therapy 2019. Link
• Zhao S, Duffield SJ, Goodson NJ. The prevalence and impact of comorbid fibromyalgia in inflammatory arthritis. Best Practice & Research Clinical Rheumatology 2019. Link
• Lyu H, Zhao S, Yoshida K, Tedeschi SK, Xu C, Nigwekar SU, Leder BZ, Solomon DH. Comparison of Teriparatide and Denosumab in Patients Switching from Long-Term Bisphosphonate Use. J Clin Endocrinol Metab 2019. Link
• Zhao S, Ermann J, Xu C, Lyu H, Tedeschi SK, Liao KP, Yoshida K, Moots RJ, Goodson NJ, Solomon DH. Comparison of comorbidities and treatment between ankylosing spondylitis and non-radiographic axial spondyloarthritis in the United States. Rheumatology 2019. Link
• Zhao S, Radner H, Siebert S, Duffield SJ, Thong D, Hughes DM, Moots RJ, Solomon DH, Goodson NJ. Comorbidity burden in axial spondyloarthritis: a cluster analysis. Rheumatology 2019. Link
• Zhao S, Solomon DH, Goodson NJ. Comment on: Comorbidity burden in axial spondyloarthritis: Reply. Link
• Zhao S, Yoshida K, Jones GT, Hughes DM, Tedeschi SK, Lyu H, Moots RJ, Solomon DH, Goodson NJ. The impact of smoking on response to TNF inhibitors in axial spondyloarthritis: methodological considerations for longitudinal observational studies. Arthritis Care & Research 2019. Link
• Lyu H, Yoshida K, Tedeschi SK, Zhao S, Xu C, Nigwekar SU, Leder B, Solomon DH. Intervals between bone mineral density testing with dual-energy X-ray absorptiometry scans in clinical practice. Osteoporosis International 2019. Link
• Zhao S, Duffield SJ, Hughes DM. Seasonal variations of Google searches for joint swelling: implications for patient-reported outcomes. Clinical rheumatology 2019. Link
• Zhao S, Hughes DM Response: To statistical significance and beyond. Link
• Zhao S, Jones GT, Macfarlane GJ, Hughes DM, Dean LE, Moots RJ, Goodson NJ. Associations between smoking and extra-axial manifestations and disease severity in axial spondyloarthritis: results from the BSRBR-AS. Rheumatology 2018. Link
• Lyu H, Jundi B, Xu C, Tedeschi SK, Yoshida K, Zhao S, Nigwekar SU, Leder BZ, Solomon DH. Comparison of denosumab vs. bisphosphonates in osteoporosis patients: A meta-analysis of randomized controlled trials. Journal of Clinical Endocrinology & Metabolism 2018. Link
• Zhao S, Thong D, Miller N, Duffield SJ, Hughes D, Chadwick L, Goodson NJ. The prevalence of depression in axial spondyloarthritis and its association with disease activity: a systematic review and meta-analysis. Arthritis Research & Therapy 2018. Link
• Duffield SJ, Miller N, Zhao S, Goodson NJ. Concomitant Fibromyalgia Complicating Chronic Inflammatory Arthritis: A Systematic Review and Meta-analysis. Rheumatology 2018. Link
• Zhao S, Thong D, Duffield SJ, Hughes D, Goodson NJ. Alcohol and disease activity in axial spondyloarthritis: a cross-sectional study. Rheumatology International 2017. Link
• Hauser B & Zhao S, Visconti M, Riches P, Fraser W, Goodson N, Ralston S. Autoantibodies to osteoprotegerin are associated with low hip bone mineral density and history of fractures in axial spondyloarthritis: a cross-sectional observational study. Calcified Tissue International 2017. Link
• Zhao S, Thong D, Duffield S, Goodson NJ. Vitamin D deficiency is associated with disease activity in axial spondyloarthritis: results from a cross-sectional study. Archives of Rheumatology 2016. Link
• Zhao S, Challoner B, Khattak M, Moots RJ, Goodson NJ. Increasing smoking intensity is associated with increased disease severity in axial spondyloarthritis. Rheumatology International 2016. Link
• Mohamed M, Patel D, Zhao S, Ballal M, Scott S. Increased mortality amongst patients sustaining neck of femur fractures as in-patients in a trauma centre. The Open Orthopaedics Journal 2015. Link
• Mutch K, Zhao S, Methley A, Elsone L, Hamid S, Singh M, YoungC, Emmanuel A, Panicker J, Jacob A. Bladder and bowel dysfunction affect quality of life. Across sectional study of 60 patients with aquaporin-4 antibody positive neuromyelitis optica spectrum disorder. Multiple Sclerosis and Related Disorders 2015. Link
• Zhao S, Gardner K, Taylor W, Marks E, Goodson N. Vitamin D assessment in primary care: Changing patterns of testing. London Journal of General Practice 2015. Link
• Zhao S, Duffield S, Moots R, Goodson N. Systematic review of association between vitamin D levels and susceptibility and disease activity of Ankylosing Spondylitis. Rheumatology 2014 Link
• Zhao S, Mutch K, Elsone L, Nurmikko T, Jacob A. Neuropathic pain in neuromyelitis optica affects activities of daily living and quality of life. Multiple Sclerosis Journal 2014. Link
• Stadler M, Zhao SS, Bowes J. A review of the advances in understanding the genetic basis of spondylarthritis and emerging clinical benefit. Best Practice & Research Clinical Rheumatology 2024. Link
• Marzo-Ortega H, Bennet AN, Coy A, Jones GT, Machado PM, Packham J, Sengupta R, Zhao SS, Gaffney K. BRITSpA at 10. Rheumatology 2024 Link
• Zhao SS, Burgess S. Use of Mendelian Randomization to assess the causal status of modifiable exposures for rheumatic diseases. Best Practice & Research Clinical Rheumatology 2024. Link
• Zhao S, Marzo-Ortega H. Psoriatic arthritis six decades on. Clin Ther 2023. Link
• Bosch P, Zhao S, Nikiphorou E. The association between comorbidities and disease activity in spondyloarthritis - a narrative review. Best Practice & Research Clinical Rheumatology 2023. Link
• Zhao S, Saxena A, Herwadkar A, Chinoy H. Diagnosis of spinal tuberculosis in an Asian patient with unexplained chronic back pain. Rheumatology 2021. Link
• Zhao S, Mackie SL, Zheng J. Why clinicians should know about mendelian randomisation. Rheumatology 2021. Link
• Zhao S, Lyu H, Yoshida K. Versatility of the clone-censor-weight approach: response to trial emulation in the presence of immortal-time bias. International Journal of Epidemiology 2020. Link
• Hng M, Zhao S, Moots RJ. An update on the general management to common vaculitides. Clinical medicine 2020. Link
• Zhao S, Moots RJ. Biomarkers for treatment response in rheumatoid arthritis: Where are they? Rheumatology and Immunology Research 2020. Link
• Dey M, Zhao S, Moots RJ. Anti-TNF biosimilars in rheumatology: the end of an era? Expert Opinion on Biological Therapy 2020. Link
• Zhao S, Goodson NJ, Robertson S, Gaffney K. Smoking in spondyloarthritis: unravelling the complexities. Rheumatology 2020. Link
• Zhao S, Chadwick L, Mysler E, Moots RJ. Review of Biosimilar trials and data on Adalimumab. Current Rheumatology Reports 2018. Link
• Chadwick L, Zhao S, Mysler E, Moots RJ. Review of Biosimilar trials and data on Etanercept. Current Rheumatology Reports 2018. Link
• Zhao S, Mysler E, Moots RJ. Etanercept in the treatment of rheumatoid arthritis. Immunotherapy 2018. Link
• Zhao S, Nair J, Moots RJ. Biosimilars: From extrapolation into off label use. Current Pharmaceutical Design 2017. Link
• Zhao S, Otieno F, Akpan A, Moots RJ. Complementary and alternative medicine use in rheumatoid arthritis: Considerations for the pharmacological management of elderly patients. Drugs and Aging 2016. Link
• Zhao S, Richardson D, Mahindrakar M, Nair J. A case of vanishing skull: Gorhams disease. Rheumatology 2017. Link
• Connor V & Zhao S, Angus R. Non-invasive ventilation for sleep disordered breathing in Smith-Magenis syndrome. BMJ case reports 2016. Link
• Zhao S, Goodson N. Diffuse Idiopathic Skeletal Hyperostosis and isotretinoin in cystic acne. BMJ case reports 2015. Link
• Zhao S, Goodson N. Smoking and comorbidities in rheumatoid arthritis: what we know and what we can do. International Journal of Clinical Rheumatology, Vol. 10, No. 1, 45-53. doi:10.2217/IJR.14.55 Link
• Zhao S, Mutch K, Elsone L, Miller J, Jacob A. An unusual case of 'itchy paralysis': Neuromyelitis optica presenting with severe neuropathic itch. Practical Neurology 2015. Link
• Gardner K, Zhao S. Vitamin D testing: three important issues. British Journal of General Practice 2014. Link
• Zhao S, Mackenzie I. Deafness: Malaria as a forgotten cause. Annals of Tropical Paediatrics 2011. Link
• Zuckerman BP, Yang Z, Warwick A, Wincup C, Russell M, Galloway JB, Zhao SS Association between interleukin-12 p40 subunit and risk of primary Sjögrens syndrome: a Mendelian randomization study. Rheumatology 2024. Link
• Preston FG, Anson M, Riley DR, Ibarburu GH, Henney A, Lip GYH, Cuthbertson DJ, Alam U, Zhao SS. SGLT2 inhibitors, but not GLP-1 receptor agonists, reduce incidence of gout in people living with type 2 diabetes across the therapeutic spectrum Clinical Therapeutics 2024. Link
• Williams J, Hum R, Alam U, Zhao SS. Insomnia and short sleep duration, but not chronotype, is associated with chronic widespread pain: Mendelian randomization study. Rheumatology International 2024. Link
• Williams J, Hum R, Rogers K, Maglio K, Alam U, Zhao SS. Metabolic Syndrome and Psoriatic Arthritis: The Role of Weight Loss as A Disease Modifying Therapy. Therapeutic Advances in Musculoskeletal Disease 2024. Link
• Gopalarathinam R, Sankar R, Zhao SS. Role of Anti-Inflammatory Diet and Fecal Microbiota Transplant in Psoriatic Arthritis. Clinical Therapeutics 2024. Link
• Hughes DM, Cuitun Coronado JI, Schofield P, Yiu ZZN, Zhao SS. The predictive accuracy of cardiovascular risk prediction tools in inflammatory arthritis and psoriasis: An observational validation study using the Clinical Practice Research Datalink. Rheumatology 2023. Link
• Dobbie LJ, Cuthbertson DJ, Hydes T, Alam U, Zhao SS. Mendelian Randomisation reveals SGLT1 inhibitions potential in Reducing NAFLD Risk. European Journal of Endocrinology 2023. Link
• Cotton C, Alton P, Hughes DM, Zhao SS. Gastro-oesophageal reflux disease, obesity and risk of idiopathic pulmonary fibrosis. Respiratory Investigations 2023. Link
• Alton P, Hughes DM, Zhao SS. Cardiovascular safety of genetically proxied IL-5 inhibition: a Mendelian randomisation study. Respiratory Investigations 2022. Link
• Pittam B, Gupta S, Harrison NL, Robertson S, Hughes DM, Zhao S. Prevalence of extra-articular manifestations in psoriatic arthritis: a systematic review and meta-analysis. Rheumatology 2020. Link
• Zhao S, Pittam B, Hughes DM. Comment: Prevalence of extra-articular manifestations in psoriatic arthritis: reply Rheumatology 2020. Link
• Gupta S, Syrimi Z, Hughes DM, Zhao S. Comorbidities in psoriatic arthritis: a systematic review and meta-analysis. Rheum Int 2021. Link
• Pittam B, Gupta S, Ahmed AE, Hughes DM, Zhao S. The prevalence and impact of depression in primary systemic vasculitis: a systematic review and meta-analysis. Rheumatology International 2020. Link
• Dey M, Zhao S. Google search data as a novel adjunct to patient and public involvement in rheumatology research. Rheumatology International 2020. Link
• Dey M, Zhao S. COVID-19 and Kawasaki disease: an analysis using Google Trends. Clinical Rheumatology 2020. Link