The liquid layer is susceptible to a capillary instability, whereby an initially uniform layer can develop a series of axisymmetric peaks and troughs, analogous to the classical instability that causes liquid jets to break up into droplets. For sufficiently high values of the liquid's surface tension, relative to the bending stiffness of the tube, the additional compressive load induced by the development of the axisymmetric instability can induce non-axisymmetric buckling of the tube wall. Once the tube has buckled, a strong destabilising feedback between the fluid and solid mechanics leads to an extremely rapid further collapse and occlusion of the gas-conveying core of the tube by the liquid. We find that such occlusion is possible even when the volume of the liquid is too small to form an occluding liquid bridge in the axisymmetric tube.