Cell Cycle Control
DNA damage intiates a signalling pathway
- DNA damage ↑ p53 activation
- Stimulates transcription of several genes
- One of these genes encodes p21 which binds to G1/S-Cdk and S Cdk, inhibiting their activities
- This blocks entry into S phase
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Lectures:
- Year 1:
- Cell Biology
- Year 2:
- Tissue Interactions and Biocompatibility
- Year 3/4:
- Tissue Engineering