Cell Cycle Control
M-Cdks
- Activation of M phase complexes trigger mitosis
- G2 has 2 copies of entire genome - sister chromatids
- Activation of mitosis occurs
- M cyclin (cyclin B) accumulates
- Subsequently M-Cdk accumulates
- Activation requires dephosphorylation
- Dephsophorylation requires activation of protein phosphatase Cdc25