Bioreactors

Mass transfer

  • In static flasks:
    • Mass transfer occurs via molecular diffusion
    • No fluid flow at surface of construct
  • In mixed flasks:
    • Mass transfer is by convection
    • Fluid flow at surface is turbulent
  • In rotating vessels:
    • Mass transfer is by convection due to settling
    • Fluid flow is laminar
  • In perfused columns and chambers:
    • Mass transfer is by convection due to recirculation
    • Fluid flow is laminar

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