Pathogens 2: Bacteria

Role of Antibody

ROLE	IgG1	IgG2	IgG3	IgG4	IgM
Neutralize toxins	+	+	+	+	+
Prevent binding to host cell	+	+	+	+	+
Opsonize for PMNs	+	-	+	-	-
Opsonize for macrophages	+	-	+	+	+
Activate complement	+	+	+	-	+

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