Surfaces

Factors affecting cell/tissue responses

Patterned surfaces

Self assembled monolayers (SAMs): control surface chemistry

Alkythiols on gold:

• Mercaptopropanoic acid HS(CH₂)₂COOH
• Mercaptopropanol HS(CH₂)₃OH
• Octanethiol HS(CH₂)₇CH₃

Cell attachment:

COOH>OH>CH3

Trend of protein adsorption and contact angles?

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