Biomaterials
Systemic toxicity
| TISSUE/ORGAN | EFFECTS |
|---|
| Lungs | Alteration in air exchange, breathing patterns |
| Kidney | Alteration in urine excretion, pain |
| Joints | Pain, swelling, loss of function |
| Liver | Alterations in blood chemistry |
| Lymphoid | Swelling, alteration in blood count |
| GI tract | Diarrhea, constipation |
Local toxicity
| TISSUE/ORGAN | EFFECTS |
|---|
| Skin | Rashes, swelling, discoloration |
| Eyes | Swelling, itchy, watery |
| Nose | Itching, running, sneezing |
Also brain, skeletal system and muscles but these do not give observable symptoms until damage is extreme