Other mechanisms under investigation
Immobilisation of human thrombomodulin (hTM)
- Endothelial cell associated glycoprotein
- hTM converts thrombin from a procoagulant protease to an anticoagulant
- Natural potent anticoagulant
Alteration of surface charge
- Inflict a negative charge
- Repels platelets by electrostatic repulsion as they are -vely charged
Hydrophilicity