Immune responses to biomaterials

Complement

Cuprophan - haemodialysis

Development of new membranes

  • Cellulose acetate
  • Polysulfone
  • Polycarbonate
  • PMMA

All these surfaces have less negatively charged groups

Results in less deposition of C3b

Therefore less C3 and C5 convertase

Therefore less C3a and C5a


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