Dr. Arpan Dutta MBChB(Hons) LLM MD PGDip FRCPsych FHEA

HONORARY SENIOR LECTURER/CONSULTANT PSYCHIATRIST/MEDICAL DIRECTOR

Faculty of Biology, Medicine and Health, Stopford Building, University of Manchester, Oxford Road, Manchester, M13 9PT

E: arpan.dutta@manchester.ac.uk

EXPERIENCE

May 2021– Medical Director – Medical & Scientific Affairs, Clinical Pharmacology Services, Covance, UK

Nov 2019– Locum Consultant Psychiatrist – Mersey Care NHS Foundation Trust, UK

Sep 2015– Honorary Senior Lecturer – University of Manchester, UK

Oct 2019–Apr 2021 Associate Medical Director – Medical & Scientific Affairs, Covance, UK

2012-2019 Consultant Psychiatrist – Mersey Care NHS Foundation Trust, UK

2010-2015 Honorary Lecturer – University of Liverpool, UK

2006-2012 Specialty Training – General & Rehabilitation Psychiatry (ST1-6), Mersey Deanery, UK

2005-2006 Foundation Programme Year 2 – Orthopaedics/Emergency Medicine/Medicine, Whiston Hospital, UK

2004-2005 Pre-Registration House Officer – Medicine/Surgery – Warrington Hospital, UK

EDUCATION

2020 FRCPsych Royal College of Psychiatrists, London, UK

2017 PGDip (Medical Education) Cardiff University, Cardiff , UK

2016 FHEA Higher Education Academy, London, UK

2015 MD (Psychiatry) University of Manchester, Manchester, UK

“The effect of NMDA receptor antagonists and antidepressants on resting state in major depressive disorder”

2013 LLM (Mental Health Law) University of Northumbria, Newcastle, UK

2012 CCT – General & rehabilitation psychiatry General Medical Council, UK

2009 MRCPsych Royal College of Psychiatrists, London, UK

2004 MBChB(Honours) University of Liverpool, Liverpool, UK

PEER-REVIEWED PUBLICATIONS

1. Nemati S, Akiki TJ, Roscoe J, Yumeng J, Averill CL, Fouda S, Dutta A, McKie S, Krystal JH, Deakin JFW, Averill LA, Abdallah CG A unique brain connectome fingerprint predates and predicts response to antidepressants. iScience 2020; 23: 100800

2. Dutta A, McKie S, Downey D, Thomas E, Juhasz G, Arnone D, Elliott R, Williams S, Deakin JFW, Anderson IM Regional default mode network connectivity in major depressive disorder; modulation by acute intravenous citalopram. Translational Psychiatry 2019; 9: 116

3. Abdallah CG, Dutta A, Averill CL, McKie S, Akiki T, Averill LA, Deakin JFW Ketamine, but not the NMDA receptor antagonist lanicemine, increases prefrontal global connectivity in depressed patients. Chronic Stress 2018; 2: 1-9

4. Downey D, Dutta A, McKie S, Dawson GR, Dourish CT, Craig K, Smith MA, McCarthy DJ, Harmer CJ, Goodwin GM, Williams S, Deakin JFW Comparing the mechanisms of lanicemine and ketamine in depression: key role of the anterior cingulate European Neuropsychopharmacology 2016; 26: 994-1003

5. Thornhill H, Dutta A Are recovery colleges socially acceptable? British Journal of Psychiatry International 2016;13(1):6-7

6. Dutta A, McKie S, Deakin JFW Ketamine and other potential glutamate antidepressants. Psychiatry Research 2015; 225: 1-13

7. Dutta A, McKie S, Deakin JFW Resting state networks in major depressive disorder. Psychiatry Research: Neuroimaging 2014;224:139-51

8. Javed Q, Dutta A Third ventricular colloid cyst and organic hypomania Progress in Neurology and Psychiatry - October 2014;18:18-20

9. Murphy L, Dutta A, Naidoo K Citalopram and psychosis. Progress in Neurology and Psychiatry 2009;13:40-41.

10. Dutta A Serotonin syndrome versus Neuroleptic Malignant Syndrome: a diagnostic dilemma. Progress in Neurology and Psychiatry 2007;11:30-33.

POSTERS

1. Nemati S, Akiki TJ, Roscoe J, Yumeng J, Averill CL, Fouda S, Dutta A, McKie S, Krystal JH, Deakin JFW, Averill LA, Abdallah CG A shift in executive connectivity predates and predicts response to treatment in major depressive disorder. Biological Psychiatry 2020; 87:S107

2. Abdallah CG, Dutta A, Averill CL, McKie S, Akiki TJ, Averill LA, Deakin JFW Ketamine, but no the NMDA receptor antagonist lanicemine., increases prefrontal global connectivity in depressed patients Poster presented at American Congress of Neuropsychopharmacology 2017.

3. Dutta A, McKie S, Downey D, Davies KE, Juhasz G, Smith MA, Williams SR, Anderson IM, Deakin JFW Does chronic citalopram pre-treatment enhance the ability of acute citalopram challenge to modulate the default mode network in healthy volunteers? Journal of Psychopharmacology 2016;30(Suppl 8):A80

4. Conen S, McKie S, Smallman R, Dutta A, Dawson GR, Smith J, Browning M, Morris R, Goodwin G, Harmer C, Christensen SR, Buchbjerg J, Larsen KG, Olsen CK, Deakin WF Effects of vortioxetine on resting-state activity in subjects remitted from depression and healthy controls. European Neuropsychopharmacology 2015;25(Suppl 2):S442

5. Dutta A, McKie S, Deakin JFW Are the acute effects of citalopram mediated by the dopamine system? European Neuropsychopharmacology 2014;24(Suppl 2):S308

6. Dutta A, McKie S, Deakin JFW Acute intravenous citalopram normalises reduced mean amplitude of low frequency fluctuations in the bilateral precuneus in major depressive disorder. Journal of Psychopharmacology 2014;28(Suppl 8):A94

7. Dutta A, McKie S, Downey D, Dourish CT, Dawson GR, McCarthy DJ, Deakin JFW Rapid antidepressant effects of lanicemine (AZD6765) may be related to effects on regions of the default mode and salience networks. Journal of Psychopharmacology 2014;28(Suppl 8):A94

8. Dutta A, Naidoo K, Willis C Prescribing in women with bipolar affective disorder of childbearing age. Poster presented at European Congress of Neuropsychopharmacology 2008.

BOOKS

1. Dutta A, Bhandary N MRCPsych CASC Notes. Lulu Publishing, 2010

AWARDS

2016 Post-doctoral bursary to attend British Association for Psychopharmacology Summer Meeting

ROYAL COLLEGE OF PSYCHIATRISTS

Feb 2019– MRCPsych CASC Examiner

2017 – 2021 Vice-Chair, Faculty of Rehabilitation & Social Psychiatry

2016 – 2019 College Assessor

2015 – 2021 Regional Specialty Representative, Mersey Region, Faculty of Rehabilitation & Social Psychiatry

2013 – 2017 Executive Committee Member, Faculty of Rehabilitation & Social Psychiatry

OTHER POSITIONS

Mar 2021– Biotech Reviewer, BioExpert Network

Feb 2021– Professional Peer Reviewer, National Institute for Health Research

Mar 2018– Review Editor, Frontiers in Psychiatry, Psychopharmacology

MEMBERSHIPS

General Medical Council– Registered with a licence to practice, Specialist Register

Fellow of the Royal College of Psychiatrists

Fellow of the Higher Education Academy

Fellow of Manchester Medical Society

Member of the European College of Neuropsychopharmacology

Member of the British Association for Psychopharmacology

Member of the British Neuroscience Association

Member of the International Society for Affective Disorders

Member of the British Association of Pharmaceutical Physicians

Affiliate Member of the Faculty of Pharmaceutical Medicine

COURSES

2021-2022 Postgraduate Course in Pharmaceutical Medicine Cardiff University/British Association of Pharmaceutical Physicians