Cell Death

Apoptosis vs necrosis

NECROSIS APOPTOSIS
Cell swells Cell shrinks
Organelles rendered non-functional Organelles remain intact
Random DNA degradation Controlled DNA degradation
General chromatin precipitation Chromatin condensation, margination
PM damaged, permeable PM remains intact
Cell ruptures Apoptotic body formation
Induction of inflammatory response Phagocytosis
Occurs in large groups of cells Occurs in individual cells

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