Our interests cover a wide range; other recent work includes structure
determinations of natural products, the first analysis of the
anomalous lineshapes that radiation damping causes in intense
multiplet signals, the construction of prototype LCNMR hardware,
an analysis of the spatial dependence of the signal strength in
Hahn and stimulated echoes, a new technique for real-time chemical shift scaling, NMR measurements of the kinetics of
processes such as hindered amine rotation, antibiotic degradation,
and bacterial reduction of DMSO and TMAO, and structural studies
on model oligonucleotides and fluoroshikimates.
·
"The acyl nitroso
Diels Alder (ANDA) reaction of
sorbate derivatives: X-ray structural analysis, novel 15N NMR
distinction between regioisomeric adducts and new applications to amino-acid
synthesis". Lee Bollans, Daniel O’Farrell,
John Bacsa, Jonathan A. Iggo, Gareth A. Morris and Andrew V. Stachulski, Org.
Biomol. Chem., 7, 4531-4538
(2009). DOI: 10.1039/B912963D
·
"Quantifying
end-to-end conformational communication of chirality through an achiral peptide
chain." J. Clayden, A. Castellanos, J. Solà and G.A. Morris, Angew.
Chemie, Int. Ed., 32, 5962-5965 (2009). DOI: 10.1002/anie.200901892
·
"Two-Dimensional
J-Resolved 2D Spectroscopy",
in Encyclopedia of Magnetic Resonance, eds R. K. Harris and R. E.
Wasylishen, John Wiley: Chichester. DOI: 10.1002/9780470034590.emrstm0579.pub2.
Published 15th September 2009.
·
Review of "Spin
Dynamics: Basics of Nuclear Magnetic Resonance", G.A. Morris, NMR in
Biomed. 22, 240-241 (2009).
·
"Helix persistence
and breakdown in oligoureas of metaphenylenediamine: apparent diastereotopicity
as a spectroscopic marker of helix length in solution." J.P. Clayden, L.
Lemiègre, G.A. Morris, M. Pickworth, T.J. Snape and L.H. Jones, J. Am. Chem.
Soc. 130, 15193-15202 (2008). DOI:
10.1021/ja805758v
·
"Mechanism for the
Degradation of Erythromycin A and Erythromycin A 2´-Ethyl Succinate in Acidic
Aqueous Solution." A. Hassanzadeh, J. Barber, G.A. Morris and P.A. Gorry,
J. Phys. Chem. A, 111, 10098-10104
(2007). DOI: 10.1021/jp073030
·
"Pediatric
Erythromycins: a comparison of the
properties of erythromycins A and B 2'-ethyl succinates", A. Hassanzadeh,
P. Gorry, G.A. Morris and J. Barber, J. Med. Chem. 49, 6334 - 6342 (2006).
·
“Improving Pulse
Sequences for 3D DOSY:
COSY-IDOSY”, Mathias Nilsson, Ana M. Gil, Ivonne Delgadillo and Gareth
A. Morris, Chem. Commun. 2005,
1737-1739.
·
“Difluorinated analogues
of shikimic acid”, L. Begum, J.M. Box, M.G.B. Drew, L.M. Harwood, J.L.
Humphreys, D.J. Lowes, G.A. Morris, P.M. Redon, F.M. Walker and R.C. Whitehead,
Tetrahedron 59, 4827-4841 (2003).
·
“Real-time chemical
shift scaling”, G.A. Morris, N.P Jerome and L.-Y. Lian, Angew. Chemie Int. Ed.,
42, 823-825 (2003).
·
"Stereodynamics of
Bond Rotation in Tertiary Aromatic Amides", R.A. Bragg, J. Clayden, G.A.
Morris and J.H. Pink, Chem. Eur. J., 8, 1279 - 1289 (2002).
·
"Dehydration of
Quinate Derivatives: Synthesis of
a Difluoromethylene Homologue of Shikimic Acid". J.M. Box, L.M. Harwood, J.L. Humphreys, G.A. Morris, P.M.
Redon and R.C. Whitehead, Synlett, 2002, 358-360.
·
"In vivo oxo
transfer: reactions of native and
W-substituted dimethylsulfoxide reductase monitored by 1H NMR spectroscopy".
L.J. Stewart, S. Bailey, D. Collison, G.A. Morris, I. Preece and C.D.
Garner, ChemBioChem, 9, 703-706
(2001).
·
“Binding of a porphyrin
conjugate of Hoechst 33258 to DNA.
Part 2. NMR spectroscopic
studies detect multiple binding modes to a 12-mer non self-complementary duplex
DNA”. A. Frau, E.V. Bichenkova,
G.A. Morris and K.T. Douglas, Nucleosides, Nucleotides and Nucleic Acids, 20, 145-156 (2001).
·
"The acid-catalysed
degradation of clarithromycin and erythromycin B: a comparative study using NMR spectroscopy", M.N.
Mordi, M.D. Pelta, V. Boote, G.A. Morris and J. Barber, J. Med.Chem., 43, 467-474 (2000).