Publications by research themes

(Publications by date / Recent publications)

 

Characterising and controlling the properties of polymeric materials

Refinement of the Crystal Structures of Forms I and II of Isotactic Polybutene-1 and a Proposal of Phase Transition Mechanism between Them K. Tashiro, J. Hu, H. Wang, M. Hanesaka, A. Saiani; Macromolecules, 49, 1392-1404 (2016)

Phase Separation and Crystallization in High Hard Block Content Polyurethane Thin Films L. Jiang, J. Wu, C. Nedolisa, A. Saiani, H.E. Assender; Macromolecules, 48, 5358-5366 (2015)

Synthesis of polyurea-polyether nanoparticles via spontaneous nanoprecipitation P. Locatelli, S. Woutters, C. Lindsay, SLM Schroeder, John H. Hobdell, A. Saiani; RSC Advances, 5, 41668-41676 (2015)

Biodegradation of polyester polyurethane during commercial composting and analysis of associated fungal communities U. Zafar, P. Nzeram, A. Langarica-Fuentes, A. Houlden, A. Heyworth, A. Saiani, G.D. Robson; Bioresource Technology, 158, 374-377 (2014)

Immobilisation of cell-binding peptides on poly-ε-caprolactone film surface to biomimic the peripheral nervous system A.C. de Luca, J.S. Stevens, S.L.M. Schroeder, J.-B. Guilbaud, A. Saiani, S. Downes, G. Terenghi; Journal of Biomedical Materials Research: Part A, 101A, 491-501 (2013)

Tunable Self-Assembled Elastomers Using Triply Hydrogen-Bonded Arrays A. Gooch,  C. Nedolisa, K.A. Houton, C.I. Lindsay, A. Saiani, A.J. Wilson; Macromolecules, 45, 4723-4729 (2012)

The impact of chemical composition on the degradation kinetics of poly(lactic-co-glycolic) acid copolymers cast films in phosphate buffer solution E. Vey, C. Roger, L. Meeham, J. Booth, M. Claybourn, A.F. Miller, A. Saiani Polymer Degradation and Stability, 97, 358-365 (2012)

Degradation kinetics of poly(lactic-co-glycolic) acid block copolymer cast films in phosphate buffer solution as revealed by infrared and Raman spectroscopies; E. Vey, C. Roger, J. Booth, M. Claybourn, A.F. Miller, A. Saiani; Polymer Degradation and Stability, 96, 1882-1889 (2011)

Effect of encapsulating a pseudo-decapeptide containing arginine on PLGA: a solid-state NMR study J.B.Guilbaud, B.C.Clark, L. Meehan, L. Hughes, A. Saiani and Y. Khimyak Journal of Pharmaceutical Sciences, 99, 2681-2696 (2010)

Particulate ionomer films prepared from dispersions of crosslinked polymer colloids: a structure-property study O. Pinprayoon, A. Saiani, R. Groves, B.R. Saunders Journal of Colloid & Interface Science, 336, 73-81 (2009)

Effect of clay dispersion on the rheological properties and flammability of polyurethane-clay nanocomposite elastomers; M. Berta, A. Saiani, C. Lindsay, R. Gunaratne Journal of Applied Polymer Science, 112, 2847-2853 (2009)

Degradation mechanism of poly(lactic-co-glycolic) acid block copolymer cast films in sulphate buffer solution; E. Vey, C. Roger, L. Meeham, J. Booth, M. Claybourn, A.F. Miller, A. Saiani; Polymer Degradation and Stability, 93, 1869-1876 (2008)

Selective synthesis of double temperature-sensitive polymer-peptide conjugates; F. Stoica, C. Alexander, N. Tirelli, A.F. Miller, A. Saiani; Chemical Communications, 4433–4435 (2008)

Origin of multiple melting endotherms in a high hard block content polyurethane: Effect of annealing temperature; A. Saiani, A. Novak, L. Rodier, G. Eeckhaut, J.-W. Leenslag, J.S. Higgins; Macromolecules, 40, 7252-7262 (2007)

Thermo-responsive PNIPAAm copolymers with hydrophobic spacers; F. Stoica, A.F. Miller, C. Alexander, A. Saiani;  Macromolecular Symposia, 251, 33-40 (2007)

In vitro degradation of poly(lactic-co-glycolic acid) random copolymers; E. Vey, A.F. Miller, M. Claybourn, A. Saiani; Macromolecular Symposia, 251, 81-87 (2007)

In vitro degradation of poly(lactic-co-glycolic) acid block copolymers E. Vey, A.F. Miller, M. Claybourn, A. Saiani Materials Research Society Symposia Proceedings, 947E, 0947-A02-04 (2007)

Gelation dynamics and mechanism(s) in stereoregular poly(methyl methacrylate)s; A. Saiani; Macromolecular Symposia, 222, 37-47 (2005)

Origin of multiple melting endotherms in a high hard block content polyurethane: 2. Structural investigation, A. Saiani, W.A. Daunch, G. Eeckhaut, J.-W. Leenslag, J.S. Higgins  Macromolecules, 37, 1411-1421 (2004)

Origin of multiple melting endotherms in a high hard block content polyurethane: 1. Thermodynamic investigation; A. Saiani, W.A. Daunch, H. Verbeke, J.-W. Leenslag, J.S. Higgins; Macromolecules, 34, 9059-9068 (2001)

Nanostructure and helicity in syndiotactic poly[methyl methacrylate] thermoreversible gels; A. Saiani, J.-M. Guenet; Macromolecules, 32, 657-663 (1999)

Phase behaviour and polymer/solvent interactions in thermoreversible gels of syndiotactic poly[methyl methacrylate]; A. Saiani, J. Spevacek, J.-M. Guenet; Macromolecules, 31, 703-710 (1998)

Crystal structure of unstable form II of isotactic polybutene 1: Structural analysis by a combination of X- ray imaging plate and computer simulation technique; K. Tashiro, A. Saiani, S. Miyashita, Y. Chatani, H. Tadokoro; Polymer Preprint, Japan,  47, 3869-3871 (1998)

Temperature-concentration phase diagrams in the study of thermoreversible gelation; D. López, A. Saiani, J.-M. Guenet; Journal of Thermal Analysis and Calorimetry, 51, 841-851 (1998)

On the helical form in syndiotactic poly[methyl methacrylate] thermoreversible gels as revealed by small-angle neutron scattering; A. Saiani, J.-M. Guenet; Macromolecules, 30, 966-972 (1997)

Existence of a poly[vinyl chloride] (PVC)-solvent compound in PVC thermoreversible gels as revealed by neutron diffraction; H. Reinecke, A. Saiani, C. Mijangos, J.-M. Guenet; Macromolecules, 29, 4799-4800 (1996)

Thermoreversible gelation of isotactic poly[methyl methacrylate] in butylacetate : a DSC study; J. Spevacek, A. Saiani, J.-M. Guenet; Macromolecular Rapid Communications, 17, 389-395 (1996)

 

Thin films at the air-water interface

Two-dimensional polymerization of a polydiacetylene functionalized amphiphilic peptide at the air-water interface M. Simon Saenz de Samaniego, A.F. Miller, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 321, 271-274 (2008)

Irreversible collapse of poly(vinyl stearate) monolayers at the air-water interface; P.G. Mussone, B.S. Murray, A.F. Miller; Langmuir, 23, 3766-3773 (2007)

Exploiting wrinkle formation A.F.Miller, Science, 2007 317 (5338) 605-606 (2007)

Neutron reflectivity and external reflection FTIR studies of dl-aspartic acid crystallisation beneath nylon 6 spread films; M. J. Jamieson, S.J. Cooper, A.F. Miller, S.A. Holt; Langmuir, 20, 3593-3600 (2004)

Inelastic neutron scattering measurements of intact cells and tissues and detection of interfacial water; R. C.Ford, S. V. Ruffle, I. Michalarias, I. Beta, A.F. Miller, A.J.Ramirez-Cuesta, J. Li; Journal of American Chemical Society, 126, 4682-4688 (2004)

Monte carlo simulation of an amphiphilic graft copolymer at a hydrophobic-hydrophilic interface; A. F. Miller, M. Cook, R. W. Richards, M. Wilson; Molecular Physics, 101, 1131-1138 (2003)

Influence of dissolved polymer on the dimensions of a tethered polymer layer for a graft copolymer spread at the air-aqueous solution interface; A. F. Miller, R. W. Richards, J. R. P. Webster; Journal of Physical Chemistry B, 107, 6717-6723 (2003)

Imaging of the isotropic/anisotropic surfaces of aqueous cellulose suspensions using environmental scanning electron microscopy; A. F. Miller, A. M. Donald; Biomacromolecules, 4, 510-517 (2003)

Surface and interfacial tension of cellulose dispersions; A. F. Miller, A. M. Donald; Langmuir, 18, 10155-10162 (2002)

In-situ imaging of nylon 6 6 polymer film at the air-water interface using environmental scanning electron microscopy; A. F. Miller, S. J. Cooper; Langmuir, 18, 1310-1317 (2002)

Transition in tethered layer thickness induced by concentration changes in a spread film of an amphiphilic graft copolymer; A.F. Miller, R.W. Richards, J.R.P. Webster; Macromolecules, 34, 8361-8369 (2001)

Organisation of well-defined graft copolymers at the air-water interface; A.F. Miller, R.W. Richards, J.R.P. Webster; Macromolecules, 33, 7618-7628 (2000)

 

Peptides: from self assembly to functional biomaterials

3D cell bioprinting of self-assembling peptide-based hydrogels B. Raphael⁠, T. Khalil⁠, V.L. Workman⁠⁠, A. Smith, C.P. Brown⁠, C. Streulli⁠, A. Saiani, M. Domingos; Materials Letters, 190, 103-106  (2017)

Self-assembling peptide hydrogel for intervertebral disc tissue engineering S. Wan, S. Borland, S.M. Richardson, C.L.R. Merry, A. Saiani and J.E. Gough; Acta Biomaterialia, 46, 29-40 (2016)

Osteogenic differentiation of human mesenchymal stem cells promotes mineralization within a biodegradable peptide-hydrogel L.A. Castillo Diaz, M. Elsawy, A. Saiani, J.E. Gough and A.F. Miller; Journal of Tissue Engineering, 7, 2041731416649789 (2016)

A de novo self-assembling peptide hydrogel biosensor with covalently immobilised DNA-recognising motifs P.J.S. King, A. Saiani, E.V. Bichenkova and A.F. Miller; Chemical Communications, 52, 6697-6700 (2016)

Modification of β-sheet forming peptide hydrophobic face: effect on self-assembly and gelation M. Elsawy, A.M. Smith, N. Hodson, A. Squires, A.F. Miller, A. Saiani; Langmuir 32, 4917-4923 (2016)

A modular self-assembly approach to functionalised b-sheet peptide hydrogel biomaterials P.J.S. King, M.G. Lizio, A. Booth, R.F. Collins, J.E. Gough, A.F. Miller and S.J. Webb; Soft Matter 12, 1915-1923 (2016)

Nanospheres from the self-assembly of an elastin-inspired triblock peptide A. Scelsi,   B. Bochicchio,   A.M. Smith,   A. Saiani and A. Pepe; RSC Advances, 5, 95007-95013 (2015)

Self-assembling peptide / thermo-responsive polymer composite hydrogels: Effect of peptide-polymer interactions on hydrogel properties A. Maslovskis, J.-B. Guilbaud, I. Grillo, N. Hodson, A.F. Miller, A. Saiani; Langmuir, 30, 10471-10480 (2014)

Enzymatically triggered peptide hydrogels for 3D cell encapsulation and culture L. Szkolar, J.-B. Guilbaud, A.F. Miller, J.E. Gough, A. Saiani; Journal of Peptide Science, 20, 578-584 (2014)

Osteoblasts within soft peptide hydrogels promote mineralisation in-vitro L.A. Castillo, A. Saiani, J.E. Gough, A.F. Miller; Journal of Tissue Engineering, 5, 1-12 (2014)

Nanofibrillar peptide hydrogels for the immobilization of biocatalysts for chemical transformations C. Hickling, H.S. Toogood, A. Saiani, N.S. Scrutton, A.F.Miller; Macromolecular Rapid Communications, 35, 868-874 (2014)

Peptide hydrogels as mucoadhesives for local drug delivery C. Tang, A.F. Miller, A. Saiani; International Journal of Pharmaceutics, 465, 427-435 (2014)

Controlling network topology and mechanical properties of co-assembling peptide Hydrogels S. Boothroyd, A. Saiani, A.F. Miller; Biopolymers, 106, 669-680 (2014)

From fibres to networks using self-assembling peptide S. Boothroyd, A.F. Miller, A. Saiani; Faraday Discussions, 166, 195-207 (2013)

Self-assembly and gelation properties of glycine / leucine Fmoc-dipeptides C. Tang, R.V. Ulijn, A. Saiani; European Physical Journal E - Soft Matter and Biological Physics, 36:111 (2013)

Site-specific, covalent incorporation of Tus, a DNA-binding protein, on ionic-complementary self-assembling peptide hydrogels using transpeptidase Sortase A as a conjugation tool S. Piluso , H.C. Cassell , J.L. Gibbons , T.E. Waller , N.J. Plant , A.F. Miller, G. Cavalli; Soft Matter, 9, 6752-6756 (2013)

Effect of Enzyme concentration of the morphology and properties of Enzymatically Triggered Peptide Hydrogels J.-B. Guilbaud, C. Rochas, A.F. Miller, A. Saiani, Biomacromolecules, 14, 1403-1411 (2013)

Self-assembled octapeptide scaffolds for in vitro chondrocyte culture A. Mujeeb, A.F. Miller, A. Saiani, J.E. Gough; Acta Biomaterialia, 9, 4609-46017 (2013)

Effect of peptide and guest charge on the structural, mechanical and release properties of β-sheet forming peptides hydrogels D. Roberts, C. Rochas, A. Saiani, A.F. Miller; Langmuir, 28, 16196–16206 (2012)

Enzymatic catalysed synthesis and gelation of ionic peptides for 3D cell culture applications J.-B. Guilbaud, L. Szkolar, A.F. Miller and A. Saiani Materials Research Society Symposia Proceedings, 1417, Online (2012)

Thiol coupling based synthesis of temperature-sensitive polymer–peptide conjugates with controlled architecture J.-B. Guilbaud, A.F. Miller and A. Saiani Materials Research Society Symposia Proceedings, 1418, Online (2012)

Peptide-PNIPAAm conjugate based hydrogels: Synthesis and characterisation A. Maslovskis, N. Tirelli, A. Saiani, and A.F. Miller Soft Matter, 7, 6025-6033 (2011)

Peptide hydrogels: Mimicking the extracellular matrix J.E. Gough, A. Saiani, A.F. Miller; Bioinspired, Biomimetic and Nanobiomaterials, 1, 4-12 (2012)

Effect of glycine substitution on Fmoc-diphenylalanine self-assembly and gelation properties; C. Tang, R.V. Ulijn; A. Saiani; Langmuir, 27, 14438-14449 (2011)

Using small angle scattering (SAS) to structurally characterise peptide and protein self-assembled materials J.-B. Guilbaud and A. Saiani Chemical Society Reviews, 40(3), 1200-1210 (2011)

Thermoresponsive hydrogels from physical mixtures of self-assembling peptide and its conjugate with PNIPAAm A. Maslovskis, A Saiani, A.F. Miller Macromolecular Symposia, 296, 248-253 (2010)

Enzyme triggered gelation of arginine containing ionic-peptides J.-B. Guilbaud, A.F. Miller and A. Saiani Materials Research Society Symposia Proceedings, 1272, 1272-NN05-04 (2010)

Enzymatic catalyzed synthesis and triggered gelation of ionic peptides J.-B. Guilbaud, E. Vey, S. Boothroyd, A.M. Smith, R.V. Ulijn. A. Saiani and A.F. Miller Langmuir, 26, 11297-11303 (2010)

Engineering peptide based biomaterials: Structure, properties and applications A.F. Miller and A. Saiani Chemistry Today Supplements Focus on Oligos & Peptides, 28 (1), 34-38 (2010)

Fmoc-diphenylalanine self-assembly mechanism induces apparent pKa shifts C. Tang, A.M. Smith, R.F. Collins, R.V. Ulijn, A. Saiani Langmuir, 25 , 9447–9453 (2009)

Introducing chemical functionality in Fmoc-peptide gels for cell culture V. Jayawarna, S.M. Richardson, A. Hirst, N.W. Hodson, A. Saiani, J.E. Gough, R.V. Ulijn Acta Biomaterialia, 5, 934-943 (2009) 

Self-assembly and gelation properties of a-helix versus b-sheet forming peptides; A. Saiani, A. Mohammed, H. Frielinghaus, R. Collins, N. Hodson, C.M. Kielty, M.J. Sherratt, A.F. Miller; Soft Matter, 5, 193-202 (2009)

Designing enzyme-triggered hydrogels for biomedical applications using self-assembling octapeptides E. Vey, A. Saiani, A.F. Miller Materials Research Society Symposia Proceedings, 1140, 163-168 (2009)

Formation of mixed ionic complementary peptide fibrils; S. Boothroyd, A. Saiani, A.F. Miller; Macromolecular Symposia, 273, 139-145 (2008)

Selective synthesis of double temperature-sensitive polymer-peptide conjugates; F. Stoica, C. Alexander, N. Tirelli, A.F. Miller, A. Saiani; Chemical Communications, 4433–4435 (2008)

Fmoc-diphenylalanine self assembles to a hydrogel via a novel architecture based on p -p interlocked b-sheets A. M. Smith, R. J. Williams, C. Tang, P. Coppo, R. F. Collins, M. L. Turner, A. Saiani, R. V. Ulijn,  Advanced Materials, 20, 37-41 (2008)

3D Networks from self-assembling ionic-complementary octa-peptides; A. Mohammed, A.F. Miller, A. Saiani; Macromolecular Symposia, 251, 88-95 (2007)

Design of nanostructured hydrogels for 3D cell culture through self assembly of Fmoc-dipeptides; V. Jayawarna, M. Ali, A.F. Miller, A. Saiani, J.E. Gough, R.V. Ulijn; Advanced Materials, 18, 611-614 (2006)

 

Understanding and exploiting protein self-assembly

Thermal Aggregation of Recombinant Protective Antigen: Aggregate Morphology and Growth Rate D.J. Belton, A.F. Miller; Journal of Biophysics, 2013, 751091 (2013)

Protein fibrillar hydrogels for 3-dimensional tissue engineering H. Yan, A. Nykanen, J. Ruokolainen, D. Farrar and A.F. Miller; Research Letters in Nanotechnology, 2009, 614301 (2009)

Thermoreversible protein fibrillar hydrogels as cell scaffolds; H. Yan, A. Nykanen, J. Ruokolainen, A. Saiani, A.F. Miller; Faraday Discussions, 139, 71–84 (2008)

Thermoreversible lysozyme hydrogels: Properties and an insight into the gelation pathway; H. Yan, H. Frielinghaus, A. Nykanen, J. Ruokolainen,, J.E. Gough, A. Saiani, A.F. Miller; Soft Matter, 4, 1313-1325 (2008)

Effect of stereoregular polyelectrolyte on protein thermal stability; H. Zhang, A. Saiani, J.-M. Guenet, R. Curtis; Macromolecular Symposia, 251, 25-32 (2007)

Gelation of a model globular protein; H. Yan, A. Saiani, A.F. Miller; Macromolecular Symposia, 251, 112-117 (2007)

Gelation of a model globular protein H. Yan, A. Saiani, A.F. Miller Materials Research Society Symposia Proceedings, 953E, 0953-G04-02 (2007)

Thermo-reversible protein hydrogel as cell scaffold; H. Yan, A. Saiani, J.E. Gough, A.F. Miller; Biomacromolecules, 7, 2776-2782 (2006)

Gelation of misfolded proteins; A. F. Miller; Macromolecular Symposia, 220, 109-114 (2005)

The formation of spherulites by amyloid fibrils of bovine insulin; M.R.H. Krebs, C.E. MacPhee, A.F. Miller, I.E. Dunlop, C.M. Dobson, A.M. Donald; Proceedings of the National Academy of Science, 101, 14420-14424 (2004)

 

Surfactant based systems

Density, DSC, X-ray and NMR measurements through the gel and lamellar phase transitions of MSPC and SMPC: observation of slow relaxation processes and mechanisms of phase transitions J.W. Jones, L. Lue, A. Saiani, G.J.T. Tiddy; Physical Chemistry Chemical Physics, 14, 5452-5469 (2012)

Phase behaviour of lyotropic liquid crystals in linear alkylbenzene sulphonate (LAS) systems in the presence of dilute and concentrated electrolyte J.A. Stewart, A. Saiani, A. Bayly, G.J.T. Tiddy Journal of Dispersion Science and Technology, 32, 1700-1710 (2011)

The phase behaviour of lyotropic liquid crystals in linear alkylbenzene sulphonate (LAS) systems; J.A. Stewart, A. Saiani, A. Bayly, G.J.T. Tiddy; Colloids and Surfaces A: Physicochemical and Engineering Aspects, 338, 155-161 (2009)

Lipid unsaturation and membrane protein has an enormous effect on the gel phase hysteresis of mixed phospholipids LW. Jones, L. Lue, M. Lorch, A. Saiani, A. Tahlawi and GJ. Tiddy Journal of Cosmetic Science, 60, 393-394 (2009)

Density measurements through the gel and lamellar phase transitions of di-tetradecanoyl- and di-hexadecanoylphosphatidylcholines: observation of slow relaxation processes and mechanisms of phase transitions; J.W. Jones, L. Lue, A. Saiani, G.J.T. Tiddy; Liquid Crystals, 32, 1465-1481 (2005)

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