Contents
- In the scientific literature
- 2002 and before, 2003, 2004 2005, 2006, 2007, 2008, 2009,
- 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019,
- 2020, 2021, 2022, 2023, 2024.
- As conference contributions
- 1996, 1997, 1998, 1999,
- 2000 - 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009,
- 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019,
- 2020, 2021, 2022, 2023, 2024.
- Patents
Hinz, R.
Parallelisierung eines iterativen Rekonstruktionsalgorithmus für
die Positronen-Emissions-Tomographie.
(Parallelisation of an iterative reconstruction algorithm for positron
emission tomography.)
Diploma Thesis, TU Chemnitz-Zwickau,
Fakultät für Elektrotechnik und Informationstechnik, 1995.
Pawelke, J.; Enghardt, W.; Haberer, T.; Hasch, B.G.; Hinz, R.; Krämer,
M.; Lauckner, K.; Sobiella, M.
In-beam PET imaging for the
control of heavy-ion tumour therapy.
IEEE Trans. Nucl. Sci. 44 (1997), 1492 - 1498.
Hinz, R.; Byars, L.; Enghardt, W.; Hasch, B.G.; Lauckner, K.; Pawelke, J.;
Sobiella, M.
A method for in-vivo treatment plan verification of heavy-ion tumour
therapy by positron emission tomography.
Physica Medica XIII, Suppl. 1 (Dec 1997), 61 - 63.
Enghardt, W.; Debus, J.; Haberer, T.; Hasch, B.G.; Hinz, R.;
Jäkel, O.; Krämer, M.; Lauckner, K.; Pawelke, J.
The application of PET to quality assurance of heavy-ion tumor therapy.
Strahlenther. Onkol. 175, suppl. 2 (1999), 33 - 36.
PMID: 10394393
Enghardt, W.; Debus, J.; Haberer, T.; Hasch, B.G.; Hinz, R.;
Jäkel, O.; Krämer, M.; Lauckner, K.; Pawelke, J.;
Pönisch, F.
Positron emission tomography for quality assurance of cancer
therapy with light ion beams.
Nuclear Physics A 654 (1999), 1047c - 1050c.
Dörr, W.; Alheit, H.; Appold, S.; Enghardt, W.; Haase, M.;
Haberer, T.; Hinz, R.; Jäkel, O.; Kellerer, A.M.; Krämer, M.;
Kraft, G.; Kumpf, R.; Nitzsche, H.; Scholz, M.; Voigtmann, L.;
Herrmann, T.
Response of pig
lung to irradiation with accelerated 12C-ions.
Radiat. Environ. Biophys. 38 (1999), 185 - 194.
PMID: 10525955
Hinz, R.
Beiträge zur Einführung der Positronen-Emissions-Tomographie bei
der Schwerionen-Tumortherapie.
(Contributions on the introduction of positron
emission tomography in heavy ion tumour therapy.)
PhD Thesis, Technische
Universität Dresden, Fakultät Elektrotechnik, 2000.
Wissenschaftlich-Technische Berichte
Forschungszentrum Rossendorf
FZR-286, February 2000.
Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; Elhalag, E.;
Fritz, A.; Steinbach, J.; Füchtner, F.; Hinz, R.; Zwiener, U.;
Johannsen, B.
Effect of hypoxia/hypercapnia on metabolism of
6-[18F]fluoro-L-DOPA in newborn piglets.
Brain Res. 934 (2002), 23 - 33.
PMID: 11937066
Brust, P.; Zessin, J.; Kuwabara, H.; Pawelke, B.; Kretzschmar, M.; Hinz,
R.; Bergman, J.; Eskola, O.; Solin, O.; Steinbach, J.; Johannsen, B.
Positron emission
tomography imaging of the serotonin transporter in the pig brain
using [11C](+)-McN5652 and
S-([18F]fluoromethyl)-(+)-McN5652.
Synapse 47 (2003), 143 - 151.
PMID: 12454952
Turkheimer, F.E.; Hinz, R.; Cunningham, V.J.
On the undecidability among kinetic models: from model selection
to model averaging.
J. Cereb. Blood Flow Metab. 23 (2003), 490 - 498.
PMID: 12679726
Brust, P.; Hinz, R.; Kuwabara, H.; Hesse, S.; Zessin, J.; Pawelke, B.;
Stephan, H.; Bergmann, R.; Steinbach, J.; Sabri, O.
In vivo measurement of the serotonin transporter with
(S)-([18F]fluoromethyl)-(+)-McN5652.
Neuropsychopharmacology 28 (2003), 2010 - 2019.
PMID: 12931143
Turkheimer, F.E.; Hinz, R.; Gunn, R.N.; Aston, J.A.D.; Gunn, S.R.;
Cunningham, V.J.
Rank-shaping regularization of exponential spectral analysis for
application to functional parametric mapping.
Phys. Med. Biol. 48 (2003), 3819 - 3841.
PMID: 14703160
Enghardt, W.; Crespo, P.; Fiedler, F.; Hinz, R.; Parodi, K.;
Pawelke, J.; Pönisch, F.
Charged hadron tumour therapy monitoring by means of PET.
Nucl. Instr. and Meth. A525 (2004), 284 - 288.
Brust, P.; Walter, B.; Hinz, R.; Füchtner, F.; Müller, M.;
Steinbach, J.; Bauer, R.
Developmental changes in the activities of aromatic amino acid
decarboxylase and catechol-O-methyltransferase in the
porcine brain: A positron emission tomography study.
Neurosci. Lett. 364 (2004), 159 - 163.
PMID: 15196667
Walter, B.; Brust, P.; Füchtner, F.; Müller, M.; Hinz, R.;
Kuwabara, H.; Fritz, H.; Zwiener, U.; Bauer, R.
Age-dependent effects of severe traumatic brain injury on
cerebral dopaminergic activity in newborn and juvenile pigs.
J. Neurotrauma 21 (2004), 1076 - 1089.
PMID: 15319007
Aston J.A.D.; Gunn, R.N.; Hinz, R.; Turkheimer, F.E.
Wavelet variance components in image space for spatiotemporal
neuroimaging data.
Neuroimage 25 (2005), 159 - 168.
PMID: 15734352
Hinz, R.; Turkheimer, F.E.
Determination of tracer arrival delay with spectral analysis.
IEEE Trans. Nucl. Sci. 53 (2006), 212 - 219.
Bhagwagar, Z.; Hinz, R.; Taylor, M.; Fancy, S.; Cowen, P.;
Grasby, P.
Increased 5-HT2A receptor binding in euthymic,
medication-free patients recovered from depression: a positron
emission study with [11C]MDL 100,907.
Am. J. Psychiatry 163 (2006), 1580 - 1587.
PMID: 16946184
Turkheimer, F.E.; Aston, J.A.D.; Asselin, M.-C.; Hinz, R.
Multi-resolution Bayesian regression in PET dynamic studies
using wavelets.
Neuroimage 32 (2006), 111 - 121.
PMID: 16644238
Hinz, R.; Bhagwagar, Z.; Cowen, P.J.; Cunningham, V.J.; Grasby, P.M.
Validation of a tracer kinetic model for the quantification of 5-HT2A
receptors in human brain with [11C]MDL 100,907.
J. Cereb. Blood Flow Metab. 27 (2007), 161 - 172.
PMID: 16685260
Turkheimer, F.E.; Edison, P.; Pavese, N.; Roncaroli, F.;
Anderson, A.N.; Hammers, A.; Gerhard, A.; Hinz, R.; Tai, Y.F.;
Brooks, D.J.
Reference and target region modeling of
[11C]-(R)-PK11195 brain studies.
J. Nucl. Med. 48 (2007), 158 - 167.
PMID: 17204713
Edison, P.; Archer, H.A.; Hinz, R.; Hammers, A.;
Pavese, N.; Tai, Y.F.; Hotton, G.; Cutler, D.; Fox, N.;
Kennedy, A.; Rossor, M.; Brooks, D.J.
Amyloid, hypometabolism and cognition in Alzheimer disease:
An [11C]PIB and[18F]FDG PET study.
Neurology 68 (2007), 501 - 508.
PMID: 17065593
Hammers, A.; Asselin, M.-C.; Hinz, R.; Kitchen, I.;
Brooks, D.J.; Duncan, J.S.; Koepp, M.J.
Upregulation of opioid receptor binding following spontaneous epileptic
seizures.
Brain 130 (2007), 1009 - 1016.
PMID: 17301080
Makrides, V.; Bauer, R.; Weber, W.; Wester, H.-J.;
Fischer, S.; Hinz, R.; Huggel, K.; Opfermann, T.; Herzau, M.;
Ganapathy, V.; Verrey, F.; Brust, P.
Preferred transport of
O-(2-[18F]fluoroethyl)-D-tyrosine
(D-FET) into the porcine brain.
Brain Res. 1147 (2007), 25 - 33.
PMID: 17343835
Hammers, A.; Asselin, M.-C.; Turkheimer, F.E.; Hinz, R.;
Osman, S.; Hotton, G.R.; Brooks, D.J.; Duncan, J.S., Koepp, M.J.
Balancing bias, reliability, noise properties and the need for
parametric maps in quantitative ligand PET: [11C]diprenorphine
test-retest data.
Neuroimage 38 (2007), 82 - 94.
PMID: 17764977
Bhagwagar, Z.; Murthy, N.V.; Selvaraj, S.; Hinz, R.;
Taylor, M.J.; Fancy, S.; Grasby, P.M.; Cowen, P.J.
5-HTT binding in recovered depressed patients and healthy
volunteers: a positron emission tomography study with
[11C]DASB.
Am. J. Psychiatry 164 (2007), 1858 - 1865.
PMID: 18056241
Hinz, R.; Selvaraj, S.; Murthy, V.N.; Bhagwagar, Z.;
Taylor, M.; Cowen, P.J.; Grasby, P.M.
Effects of citalopram infusion on the serotonin transporter binding of [11C]DASB
in healthy controls.
J. Cereb. Blood Flow Metab. 28 (2008), 1478 - 1490.
PMID: 18478022
Edison, P.; Archer, H.A.; Gerhard, A.; Hinz, R.;
Pavese, N.; Turkheimer, F.E.; Hammers, A.; Tai, Y.F.;
Fox, N.; Kennedy, A.; Rossor, M.; Brooks, D.J.
Microglia, amyloid, and cognition in Alzheimer's disease:
An [11C](R)PK11195-PET and [11C]PIB-PET study.
Neurobiol. Dis. 32 (2008), 412 - 419.
PMID: 18786637
Selvaraj, S.; Hoshi, R.; Bhagwagar, Z.; Murthy, N.V.;
Hinz, R.; Cowen, P.; Curran, H.V.; Grasby, P.
Brain serotonin transporter binding in former users of MDMA ('ecstasy').
Br. J. Psychiatry 194 (2009), 355 - 359.
PMID: 19336788
Edison, P.; Brooks, D.J.; Turkheimer, F.E.; Archer, H.A.;
Hinz, R.
Strategies for the generation of parametric images of
[11C]PIB with plasma input functions considering
discriminations and reproducibility.
Neuroimage 48 (2009), 329 - 338.
PMID: 19591948
Meyer, P.T.; Bhagwagar, Z.; Cowen, P.J.; Cunningham, V.J.;
Grasby, P.M.; Hinz, R.
Simplified quantification of 5-HT2A receptors in
the human brain with [11C]MDL 100,907 PET and
non-invasive kinetic analyses.
Neuroimage 50 (2010), 984 - 993.
PMID: 20083209
Kenny, L.M.; Contractor; K.B.; Hinz, R.;
Stebbing, J.; Palmieri, C.; Jiang, J.; Shousha, S.;
Al-Nahhas, A.; Coombes, R.C.; Aboagye, E.O.
Reproducibility of [11C]choline-positron emission
tomography and effect of trastuzumab.
Clin. Cancer Res. 16 (2010), 4236 - 4245.
PMID: 20682702
Lamare, F.; Hinz, R.; Gaemperli, O.; Pugliese, F.;
Mason, J.C.; Spinks, T.J.; Camici, P.G.; Rimoldi, O.E.
Detection and quantification of large vessel inflammation
with 11C-(R)-PK11195 PET/CT.
J. Nucl. Med. 52 (2011), 33 - 39.
PMID: 21149475
Selvaraj, S.; Murthy, N.V.; Bhagwagar, Z.; Bose, S.K.;
Hinz, R.; Grasby, P.M.; Cowen, P.J.
Diminished brain 5-HT transporter binding in major
depression: a positron emission tomography study with
[11C]DASB.
Psychopharmacology (Berl) 213 (2011), 555 - 562.
PMID: 19756523
Drake, C.; Boutin, H.; Jones, M.S.; Denes, A.; McColl, B.W.;
Selvarajah, J.R.; Hulme, S.; Georgiou, R.F.; Hinz, R.;
Gerhard, A.; Vail, A.; Prenant, C.; Julyan, P.; Maroy, R.; Brown, G.;
Smigova, A.; Herholz, K.; Kassiou, M.; Crossman, D.; Francis, S.;
Proctor, S.D.; Russell, J.C.; Hopkins, S.J.; Tyrrell, P.J.;
Rothwell, N.J.; Allan, S.M.
Brain inflammation is induced by co-morbidities and
risk factors for stroke.
Brain Behav. Immun. 25 (2011), 1113 - 1122.
PMID: 21356305
Bose, S.K.; Mehta, M.A.; Selvaraj, S.; Howes, O.D.;
Hinz, R.; Rabiner, E.A.; Grasby, P.M.; Turkheimer, F.E.;
Murthy, V.
Presynaptic 5-HT1A is related to 5-HTT receptor density in the
human brain.
Neuropsychopharmacology 36 (2011), 2258 - 2265.
PMID: 21750580
Edison, P.; Hinz, R.; Brooks, D.J.
Technical aspects of amyloid imaging for Alzheimer's disease.
Alzheimers Res. Ther. 3 (2011), 25.
PMID: 21888692
Turkheimer, F.E.; Selvaraj, S.; Hinz, R.; Murthy, V.;
Bhagwagar, Z.; Grasby, P.; Howes, O.; Rosso, L.; Bose, S.K.
Quantification of ligand PET studies using a reference region
with a displaceable fraction: application to occupancy studies
with [11C]-DASB as an example.
J. Cereb. Blood Flow Metab. 32 (2012), 70 - 80.
PMID: 21811290
Edison, P.; Hinz, R.; Ramlackhansingh, A.; Thomas, J.;
Gelosa, G.; Archer, H.A.; Turkheimer, F.E.; Brooks, D.J.
Can target-to-pons ratio be used as a reliable method for the
analysis of [11C]PIB brain scans?
Neuroimage 60 (2012), 1716 - 1723.
PMID: 22306804
Hinz, R.
Tracer imaging.
In:
Biomedical imaging: principles and applications (Salzer, R., editor),
Hoboken (New Jersey): John Wiley & Sons (2012).
ISBN: 978-0-470-64847-6 (hardback), 215 - 247.
Yaqub, M.; van Berckel, B.N.; Schuitemaker, A.; Hinz, R.;
Turkheimer, F.E.; Tomasi, G.; Lammertsma, A.A.; Boellaard, R.
Optimization of supervised cluster analysis for extracting
reference tissue input curves in (R)-[11C]PK11195
brain PET studies.
J. Cereb. Blood Flow Metab. 32 (2012), 1600 - 1608.
PMID: 22588187
Rylands, A.J.; Hinz, R.; Jones, M.; Holmes, S.E.; Feldmann, M.;
Brown, G.; McMahon, A.W.; Talbot, P.S.
Pre- and postsynaptic serotonergic differences in males with
extreme levels of impulsive aggression without callous unemotional traits:
a PET study using 11C-DASB and 11C-MDL100907.
Biol. Psychiatry 72 (2012), 1004 - 1011.
PMID: 22835812
Nordberg, A.; Carter, S.F.; Rinne, J.; Drzezga, A.; Brooks, D.J.;
Vandenberghe, R.; Perani, D.; Forsberg, A.; Långström, B.;
Scheinin, N.; Karrasch, M.; Någren, K.; Grimmer, T.;
Miederer, I.; Edison, P.; Okello, A.; Van Laere, K.;
Nelissen, N.; Vandenbulcke, M.; Garibotto, V.; Almkvist, O.;
Kalbe, E.; Hinz, R.; Herholz, K.
A European multicentre PET study of fibrillar amyloid in Alzheimer's
disease.
Eur. J. Nucl. Med. Mol. Imaging 40 (2013), 104 - 114.
PMID: 22961445
Yeh, H.-H.; Tian, M.; Hinz, R.; Young, D.; Shavrin, A.;
Mukhapadhyay, U.; Flores, L.G.; Balatoni, J.; Soghomonyan, S.;
Jeong, H.J.; Pal, A.; Uthamanthil, R.; Jackson, J.N.;
Nishii, R.; Mizuma, H.; Onoe, H.; Kagawa, S.; Higashi, T.;
Fukumitsu, N.; Alauddin, M.; Tong, W.; Herholz, K.; Gelovani, J.G.
Imaging epigenetic regulation by histone deacetylases in
the brain using PET/MRI with 18F-FAHA.
Neuroimage 64 (2013), 630 - 639.
PMID: 22995777
Edison, P.; Carter, S.F.; Rinne, J.O.; Gelosa, G.;
Herholz, K.; Nordberg, A.; Brooks, D.J.; Hinz, R.
Comparison of MRI based and PET template based approaches
in the quantitative analysis of amyloid imaging with
PIB-PET.
Neuroimage 70 (2013), 423 - 433.
PMID: 23261639
Walter, B.; Eiselt, M.; Cumming, P.; Xiong, G.; Hinz, R.;
Uthe, S.; Brust, P.; Bauer, R.
Resistance of brain glucose metabolism to thiopental-induced
CNS depression in newborn piglets.
Int. J. Dev. Neurosci. 31 (2013), 157 - 164.
PMID: 23305916
Edison, P.; Ahmed, I.; Fan, Z.; Hinz, R.; Gelosa, G.;
Ray Chaudhuri, K.; Walker, Z.; Turkheimer, F.E.; Brooks, D.J.
Microglia, amyloid, and glucose metabolism in Parkinson's
disease with and without dementia.
Neuropsychopharmacology 38 (2013), 938 - 949.
PMID: 23303049
Su, Z.; Herholz, K.; Gerhard, A.; Roncaroli, F.; Du Plessis, D.;
Jackson, A.; Turkheimer, F.; Hinz, R.
[11C]-(R)PK11195 tracer kinetics in the brain
of glioma patients and a comparison of two referencing approaches.
Eur. J. Nucl. Med. Mol. Imaging 40 (2013), 1406 - 1419.
PMID: 23715902
Feldmann, M.; Asselin, M.-C.; Liu, J.; Wang, S.; McMahon, A.;
Anton-Rodriguez, J.; Walker, M.; Symms, M.; Brown, G.,
Hinz, R.; Matthews, J.; Bauer, M.; Langer, O.;
Thom, M.; Jones, T.; Vollmar, C.; Duncan, J.S.;
Sisodiya, S.M.; Koepp, M.J.
P-glycoprotein expression and function in patients with
temporal lobe epilepsy: a case-control study.
Lancet Neurol. 12 (2013), 777 - 785.
PMID: 23786896
Grachev, I.D.; Doder, M.; Brooks, D.J.; Hinz, R.
Quantitative in vivo imaging of adenosine A2A
receptors in the human brain using 11C-SCH442416 PET:
a pilot study.
J. Diagn. Imaging Ther. 1 (2014), 1 - 19.
Grachev, I.D.; Doder, M.; Brooks, D.J.; Hinz, R.
An in vivo positron emission tomography study
of adenosine 2A receptor occupancy by preladenant
using 11C-SCH442416 in healthy subjects.
J. Diagn. Imaging Ther. 1 (2014), 20 - 48.
Herholz, K.; Evans, R.; Anton-Rodriguez, J.; Hinz, R.;
Matthews, J.C.
The effect of 18F-florbetapir dose reduction on region-based
classification of cortical amyloid deposition.
Eur. J. Nucl. Med. Mol. Imaging 41 (2014), 2144 - 2149.
PMID: 25002030
Kobylecki, C.; Langheinrich, T.; Hinz, R.; Vardy, E.L.R.C.;
Brown, G.; Martino, M.-E.; Haense, C.; Richardson, A.M.;
Gerhard, A.; Anton-Rodriguez, J.M.; Snowden, J.S.; Neary, D.;
Pontecorvo, M.J.; Herholz, K.
18F-florbetapir positron emission tomography in patients with
frontotemporal dementia and Alzheimer's disease.
J. Nucl. Med. 56 (2015), 386 - 391.
PMID: 25655625
Su, Z.; Roncaroli, F.; Durrenberger, P.F.; Coope, D.J.;
Karabatsou, K.; Hinz, R.; Thompson, G.; Turkheimer, F.E.;
Janczar, K.; Du Plessis, D.; Brodbelt, A.; Jackson, A.;
Gerhard, A.; Herholz, K.
The 18-kDa mitochondrial translocator protein in human gliomas:
an 11C-(R)PK11195 PET imaging and neuropathology
study.
J. Nucl. Med. 56 (2015), 512 - 517.
PMID: 25722450
Hinz, R.; Boellaard, R.
Challenges of quantification of TSPO in the human brain.
Clin. Transl. Imaging 3 (2015), 403 - 416.
Hunter, H.J.A.; Hinz, R.; Gerhard, A.; Talbot, P.S.;
Su, Z.; Holland, G.; Hopkins, S.J.; Griffiths, C.E.M.; Kleyn, C.E.
Brain inflammation and psoriasis: a [11C]-(R)-PK11195
positron emission tomography study.
Br. J. Dermatol. 175 (2016), 1082 - 1084.
PMID: 25819441
Fan, Z.; Calsolaro, V.; Atkinson, R.A.; Femminella, G.D.;
Waldman, A.; Buckley, C.; Trigg, W.; Brooks, D.J.;
Hinz, R.; Edison, P.
Flutriciclamide (18F-GE180) PET: first in
human PET study of novel 3rd generation in
vivo marker of human translator protein.
J. Nucl. Med. 57 (2016), 1753 - 1759.
PMID: 27261523
Holmes, S.E.; Hinz, R.; Drake, R.J.; Gregory, C.J.;
Conen, S.; Matthews, J.C.; Anton-Rodriguez, J.M.; Gerhard, A.;
Talbot, P.S.
In-vivo imaging of brain microglial activity in
antipsychotic-free and medicated schizophrenia:
a [11C](R)-PK11195 positron
emission tomography study.
Mol. Psychiatry 21 (2016), 1672 - 1679.
PMID: 27698434
Sridharan, S.; Lepelletier, F.X.; Trigg, W.; Banister, S.;
Reekie, T.; Kassiou, M.; Gerhard, A.; Hinz, R.; Boutin, H.
Comparative evaluation of three TSPO PET radiotracers in a
LPS-induced model of mild neuroinflammation in rats.
Mol. Imaging Biol. 19 (2017), 77 - 89.
PMID: 27481358
McGinnity, C.J.; Riaño Barros, D.A.; Rosso, L.; Veronese, M.;
Rizzo, G.; Bertoldo, A.; Hinz, R.; Turkheimer, F.E.;
Koepp, M.J.; Hammers, A.
Test-retest reproducibility of quantitative binding measures of
[11C]Ro15-4513, a PET ligand for GABAA
receptors containing alpha5 subunits.
Neuroimage 152 (2017), 270 - 282.
PMID: 28292717
Parbo, P.; Ismail, R.; Hansen, K.V.; Amidi, A.; Mårup, F.H.;
Gottrup, H.; Brændgaard, H.; Eriksson, B.O.; Eskildsen, S.F.;
Lund, T.E.; Tietze, A.; Edison, P.; Pavese, N.; Stokholm, M.G.;
Borghammer, P.; Hinz, R.; Aanerud, J.; Brooks, D.J.
Brain inflammation accompanies amyloid in the majority of
mild cognitive impairment cases due to Alzheimer's disease.
Brain 140 (2017), 2002 - 2011.
PMID: 28575151
Holmes, S.E.; Hinz, R.; Conen, S.; Gregory, C.J.;
Matthews, J.C.; Anton-Rodriguez, J.M.; Gerhard, A.;
Talbot, P.S.
Elevated translocator protein in anterior cingulate
in major depression and a role for inflammation in
suicidal thinking: a PET study.
Biol. Psychiatry 83 (2018), 61 - 69.
PMID: 28939116
Abid, K.A.; Sobowale, O.A.; Parkes, L.M.; Naish, J.; Parker, G.J.M.;
du Plessis, D.; Brough, D.; Barrington, J.; Allan, S.M.; Hinz, R.;
Parry-Jones, A.R.
Assessing inflammation in acute intracerebral hemorrhage with
PK11195 PET and dynamic contrast-enhanced MRI.
J. Neuroimaging 28 (2018), 158 - 161.
PMID: 29064155
Rissanen, E.; Tuisku, J.; Vahlberg, T.; Sucksdorff, M.; Paavilainen, T.;
Parkkola, R.; Rokka, J.; Gerhard, A.; Hinz, R.; Talbot, P.S.;
Rinne, J.O.; Airas, L.
Microglial activation, white matter tract damage, and disability
in MS.
Neurol. Neuroimmunol. Neuroinflamm. 5 (2018), e443.
PMID: 29520366
Fan, Z.; Dani, M.; Femminella, G.D.; Wood, M.; Calsolaro, V.; Veronese, M.;
Turkheimer, F.; Gentleman, S.; Brooks, D.J.; Hinz, R.; Edison, P.
Parametric mapping using spectral analysis for 11C-PBR28 PET reveals
neuroinflammation in mild cognitive impairment subjects.
Eur. J. Nucl. Med. Mol. Imaging 45 (2018), 1432 - 1441.
PMID: 29523926
McGinnity, C.J.; Riaño Barros, D.A.; Trigg, W.; Brooks, D.J.;
Hinz, R.; Duncan, J.S.; Koepp, M.J.; Hammers, A.
Simplifying [18F]GE-179 PET: are both arterial blood
sampling and 90-min acquisitions essential?
EJNMMI Res. 8 (2018), 46.
PMID: 29892810
Parbo, P.; Ismail, R.; Sommerauer, M.; Stokholm, M.G.; Hansen, A.K.;
Hansen, K.V.; Amidi, A.; Schaldemose, J.L.; Gottrup, H.;
Brændgaard, H.; Eskildsen, S.F.; Borghammer, P.;
Hinz, R.; Aanerud, J.; Brooks, D.J.
Does inflammation precede tau aggregation in early Alzheimer's disease?
A PET study.
Neurobiol. Dis. 117 (2018), 211 - 216.
PMID: 29902557
Konijnenberg, E.; Carter, S.F.; ten Kate, M.; den Braber, A.;
Tomassen, J.; Amadi, C.; Wesselman, L.; Nguyen, H.-T.;
van de Kreeke, J.A.; Yaqub, M.; Demuru, M.; Mulder, S.D.;
Hillebrand, A.; Bouwman, F.H.; Teunissen, C.E.; Serné, E.H.;
Moll, A.C.; Verbraak, F.D.; Hinz, R.; Pendleton, N.;
Lammertsma, A.A.; van Berckel, B.N.M.; Barkhof, F.; Boomsma, D.I.;
Scheltens, P.; Herholz, K.; Visser, P.J.
The EMIF-AD PreclinAD study: study design
and baseline cohort overview.
Alzheimers Res. Ther. 10 (2018), 75.
PMID: 30075734
Dani, M.; Wood, M.; Mizoguchi, R.; Fan, Z.; Walker, Z.;
Morgan, R.; Hinz, R.; Biju, M.; Kuruvilla, T.;
Brooks, D.J.; Edison, P.
Microglial activation correlates in vivo with both
tau and amyloid in Alzheimer's disease.
Brain 141 (2018), 2740 - 2754.
PMID: 30052812
Lillethorup T.P.; Glud, A.N.; Landeck, N.; Alstrup, A.K.O.;
Jakobsen, S.; Vang, K.; Doudet, D.J.; Brooks, D.J.; Kirik, D.;
Hinz, R.; Sørensen, J.C.; Landau, A.M.
In vivo quantification of glial activation in minipigs
overexpressing human α-synuclein.
Synapse 72 (2018), e22060.
PMID: 30009467
Legdeur, N.; Badissi, M.; Carter, S.F.; de Crom, S.; van de Kreeke, A.;
Vreeswijk, R.; Trappenburg, M.C.; Oudega, M.L.; Koek, H.L.;
van Campen, J.P.; Keijsers, C.J.P.W.; Amadi, C.; Hinz, R.;
Gordon, M.F.; Novak, G.; Podhorna, J.; Serné, E.;
Verbraak, F.; Yaqub, M.; Hillebrand, A.; Griffa, A.;
Pendleton, N.; Kramer, S.E.; Teunissen, C.E.; Lammertsma, A.;
Barkhof, F.; van Berckel, B.N.M.; Scheltens, P.; Muller, M.;
Maier, A.B.; Herholz, K.; Visser, P.J.
Resilience to cognitive impairment in the oldest-old:
design of the EMIF-AD 90+ study.
BMC Geriatr. 18 (2018), 289.
PMID: 30477432
McGinnity, C.J.; Årstad, E.; Beck, K., Brooks, D.J.; Coles, J.P.;
Duncan, J.S.; Galovic, M.; Hinz, R.; Hirani, E.; Howes, O.D.;
Jones, P.A.; Koepp, M.J.; Luo, F.; Riaño Barros, D.A.; Singh, N.;
Trigg, W.; Hammers, A.
Comment on "In vivo [18F]GE-179 brain signal
does not show NMDA-specific modulation with drug challenges in rodents
and nonhuman primates".
ACS Chem. Neurosci. 10 (2019), 768 - 772.
PMID: 30346706
Asghar, M.; Hinz, R.; Herholz, K.; Carter, S.F.
Dual-phase [18F]florbetapir in frontotemporal dementia.
Eur. J. Nucl. Med. Mol. Imaging 46 (2019), 304 - 311.
PMID: 30569187
Lewis, D.; Roncaroli, F.; Agushi, E.; Mosses, D.; Williams, R.;
Li, K.-L.; Zhu, X.; Hinz, R.; Atkinson, R.; Wadeson, A.;
Hulme, S.; Mayers, H.; Stapleton, E.; Lloyd, S.K.L.; Freeman, S.R.;
Rutherford, S.A.; Hammerbeck-Ward, C.; Evans, D.G.; Pathmanaban, O.;
Jackson, A.; King, A.T.; Coope, D.
Inflammation and vascular permeability correlate with growth
in sporadic vestibular schwannoma.
Neuro Oncol. 21 (2019), 314 - 325.
PMID: 30388263
Lilleker, J.B.; Hodgson, R.; Roberts, M.; Herholz, K.;
Howard, J.; Hinz, R.; Chinoy, H.
[18F]Florbetapir positron emission tomography:
identification of muscle amyloid in inclusion body myositis
and differentiation from polymyositis.
Ann. Rheum. Dis. 78 (2019), 657 - 662.
PMID: 30760470
Femminella, G.D.; Dani, M.; Wood, M.; Fan, Z.; Calsolaro, V.;
Atkinson, R.; Edginton, T.; Hinz, R.; Brooks, D.J.;
Edison, P.
Microglial activation in early Alzheimer trajectory
is associated with higher gray matter volume.
Neurology 92 (2019), e1331 - e1343.
Dryad Digital Repository.
PMID: 30796139
Perani, D.; Iaccarino, L.; Jacobs, A.H.; Lammertsma, A.A.;
Nordberg, A.; Windhorst, A.D.; Gerhard, A.; Winkeler, A.;
Gee, A.; Kuhnast, B.; Halldin, C.; Brooks, D.; Rodriguez-Vieitez, E.;
Turkheimer, F.E.; López-Picón, F.; Knudsen, G.M.;
Vercouillie, J.; Rinne, J.O.; Herholz, K.; Van Laere, K.;
Santiago-Ribeiro, M.J.; Herth, M.M.; Carroll, M.A.; Bottlaender, M.;
Hansson, O.; Edison, P.; Hinz, R.; Boellaard, R.; Moresco, R.M.;
Pappata, S.
Application of advanced brain positron emission tomography-based
molecular imaging for a biological framework in neurodegenerative
proteinopathies.
Alzheimers Dement. (Amst.) 11 (2019), 327 - 332.
PMID: 31080871
Perani, D.; Iaccarino, L.; Lammertsma, A.A.; Windhorst, A.D.; Edison, P.;
Boellaard, R.; Hansson, O.; Nordberg, A.; Jacobs, A.H.; Bottlaender, M.;
Brooks, D.; Carroll, M.A.; Chalon, S.; Gee, A.; Gerhard, A.; Halldin, C.;
Herholz, K.; Herth, M.M.; Hinz, R.; Knudsen, G.M.; Kuhnast, B.;
López-Picón, F.; Moresco, R.M.; Pappata, S.; Rinne, J.O.;
Rodriguez-Vieitez, E.; Santiago-Ribeiro, M.J.; Turkheimer, F.E.;
Van Laere, K.; Varrone, A.; Vercouillie, J.; Winkeler, A.
A new perspective for advanced positron emission tomography-based
molecular imaging in neurodegenerative proteinopathies.
Alzheimers Dement. 15 (2019), 1081 - 1103.
PMID: 31230910
Dani, M.; Wood, M.; Mizoguchi, R.; Fan, Z.; Edginton, T.;
Hinz, R.; Win, Z.; Brooks, D.J.; Edison, P.
Tau aggregation correlates with amyloid deposition in both
Mild Cognitive Impairment and Alzheimer's Disease subjects.
J. Alzheimers Dis. 70 (2019), 455 - 465.
PMID: 31256120
Flaus, A.; Riaño Barros, D.A.; Hinz, R.; Myers, J.F.;
Lingford-Hughes, A.; Koepp, M.J.; Hammers, A.; McGinnity, C.J.
Decreased GABA-A receptor binding in association with
β-lactam antibiotic use.
Clin. Nucl. Med. 44 (2019), 981 - 982.
PMID: 31693618
Visi, E.; Hinz, R.; Punter, M.; Majid, A.; Gerhard, A.; Herholz, K.
Positron emission tomography to image cerebral neuroinflammation in
ischaemic stroke: a pilot study.
Efficacy Mech. Eval. 7 (2020), 1 - 26.
PMID: 32023020
Ilyas-Feldmann, M.; Asselin, M.-C.; Wang, S.; McMahon, A.;
Anton-Rodriguez, J.; Brown, G.; Hinz, R.; Duncan, J.S.;
Sisodiya, S.M.; Koepp, M.
P-glycoprotein overactivity in epileptogenic developmental lesions
measured in vivo using (R)-[11C]verapamil PET.
Epilepsia 61 (2020), 1472 - 1480.
PMID: 32627849
McGinnity, C.J.; Riaño Barros, D.A.; Hinz, R.;
Myers, J.F., Yaakub, S.N.; Thyssen, C.; Heckemann, R.A.; De Tisi, J.;
Duncan, J.S.; Sander, J.W.; Lingford-Hughes, A.; Koepp, M.J.; Hammers, A.
Alpha 5 subunit-containing GABAA receptors in
temporal lobe epilepsy with normal MRI.
Brain Commun. 3 (2021), fcaa190.
PMID: 33501420
Mullin, S.; Stokholm, M.G.; Hughes, D.; Mehta, A.; Parbo, P.;
Hinz, R.; Pavese, N.; Brooks, D.J.; Schapira, A.
Brain microglial activation increased in glucocerebrosidase (GBA)
mutation carriers without Parkinson's disease.
Mov. Disord. 36 (2021), 774 - 779.
PMID: 33278043
Conen, S.; Gregory, C.J.; Hinz, R.; Smallman, R.;
Corsi-Zuelli, F.; Deakin, B.; Talbot, P.S.
Neuroinflammation as measured by positron emission tomography
in patients with recent onset and established schizophrenia:
implications for immune pathogenesis.
Mol. Psychiatry 26 (2021), 5398 - 5406.
PMID: 32606376
Calsolaro, V.; Matthews, P.M.; Donat, C.K.; Livingston, N.R.;
Femminella, G.D.; Guedes, S.S.; Myers, J.; Fan, Z.;
Tyacke, R.J.; Venkataraman, A.V.; Perneczky, R.; Gunn, R.;
Rabiner, E.A.; Gentleman, S.; Parker, C.A.; Murphy, P.S.;
Wren, P.B.; Hinz, R.; Sastre, M., Nutt, D.J.; Edison, P.
Astrocyte reactivity with late-onset cognitive impairment assessed
in vivo using 11C-BU99008 PET and its relationship with
amyloid load.
Mol. Psychiatry 26 (2021), 5848 - 5855.
PMID: 34267329
Langheinrich, T.; Kobylecki, C.; Jones, M.; Thompson, J.C.;
Snowden, J.S.; Hinz, R.; Pickering-Brown, S.; Mann, D.;
Roncaroli, F.; Herholz, K.; Gerhard, A.
Amyloid-PET positive patient with bvFTD: wrong diagnosis,
false positive scan, or co-pathology?
Neurol. Clin. Pract. 11 (2021), e952 - e955.
PMID: 34992994
Wimberley, C.; Lavisse, S.; Hillmer, A.; Hinz, R.;
Turkheimer, F.; Zanotti-Fregonara, P.
Kinetic modeling and parameter estimation of TSPO PET
imaging in the human brain.
Eur. J. Nucl. Med. Mol. Imaging 49 (2021), 246 - 256.
PMID: 33693967
Livingston, N.R.; Calsolaro, V.; Hinz, R.; Nowell, J.;
Raza, S.; Gentleman, S.; Tyacke, R.J.; Myers, J.;
Venkataraman, A.V.; Perneczky, R.; Gunn, R.N.;
Rabiner, E.A.; Parker, C.A.; Murphy, P.S.;
Wren, P.B.; Nutt, D.J.; Matthews, P.M.; Edison, P.
Relationship between astrocyte reactivity, using novel
11C-BU99008 PET, and glucose metabolism,
grey matter volume and amyloid load in
cognitively impaired individuals.
Mol. Psychiatry 27 (2022), 2019 - 2029.
PMID: 35125495
Dickie, B.R.; Jin, T.; Wang, P.; Hinz, R.; Harris, W.;
Boutin, H.; Parker, G.J.; Parkes, L.M.; Matthews, J.C.
Quantitative kinetic modelling and mapping of cerebral
glucose transport and metabolism using glucoCESL MRI.
J. Cereb. Blood Flow Metab. 42 (2022), 2066 - 2079.
PMID: 35748031
Michalowska, M.M.; Herholz, K.; Hinz, R.; Amadi, C.;
McInnes, L.; Anton-Rodriguez, J.M.; Karikari, T.K.;
Blennow, K.; Zetterberg, H.; Ashton, N.J.; Pendleton, N.; Carter, S.F.
Evaluation of in vivo staging of amyloid deposition in cognitively
unimpaired elderly aged 78-94.
Mol. Psychiatry 27 (2022), 4335 - 4342.
PMID: 35858992
Harris, W.J.; Asselin, M.-C.; Hinz, R.; Parkes, L.M.;
Allan, S.; Schiessl, I.; Boutin, H.; Dickie, B.R.
In vivo methods for imaging blood-brain barrier function
and dysfunction.
Eur. J. Nucl. Med. Mol. Imaging 50 (2023), 1051 - 1083.
PMID: 36437425
Leng, F.; Hinz, R.; Gentleman, S.; Hampshire, A.;
Dani, M.; Brooks, D.J.; Edison, P.
Neuroinflammation is independently associated with brain network
dysfunction in Alzheimer's disease.
Mol. Psychiatry 28 (2023), 1303 - 1311.
PMID: 36474000
Bochicchio, D.; Christie, L.; Lawrence, C.B.; Herholz, K.;
Parker, C.A.; Hinz, R.; Boutin, H.
Measurement of protein synthesis rate in rat by
[11C]leucine PET imaging: application
to the TgF344-AD model of Alzheimer's disease.
Mol. Imaging Biol. 25 (2023), 596 - 605.
PMID: 36538180
Kübler, D.; Kobylecki, C.; McDonald, K.R.; Anton-Rodriguez, J.M.;
Herholz, K.; Carter, S.F.; Hinz, R.; Thompson, J.C.; Al-Fatly, B.;
Gerhard, A.
Structural and metabolic correlates of neuropsychological profiles in
multiple system atrophy and Parkinson's disease.
Parkinsonism Relat. Disord. 107 (2023), 105277.
PMID: 36621156
Gerhard, A.; Sharples, R.; Goerttler, T.; McDonald, K.; Visi, E.;
Hinz, R.; Turkheimer, F.; Lewzey, I.; Herholz, K.; Jacobs, A.H.;
Holmes, C.
The effect of the tumour necrosis factor-alpha-inhibitor etanercept
on microglial activation patients with mild cognitive impairment—a
PET study.
Explor. Neurosci. 2 (2023), 52 - 66.
Laaksonen, S.; Saraste, M.; Nylund, M.; Hinz, R.;
Snellman, A.; Rinne, J.; Matilainen, M.; Airas, L.
Sex-driven variability in TSPO-expressing microglia in MS
patients and healthy individuals.
Front. Neurol. 15 (2024), 1352116.
@(#)publications.html 4.5 24/02/06 09:01:04 © Rainer Hinz, The University of Manchester.